GB1410319A - 6-aza-3h-1,4-benzodiazepines - Google Patents
6-aza-3h-1,4-benzodiazepinesInfo
- Publication number
- GB1410319A GB1410319A GB2330874A GB2330874A GB1410319A GB 1410319 A GB1410319 A GB 1410319A GB 2330874 A GB2330874 A GB 2330874A GB 2330874 A GB2330874 A GB 2330874A GB 1410319 A GB1410319 A GB 1410319A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkoxy
- alkyl
- compounds
- alkylimino
- chloropyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BTQDZLVHRYXJDK-UHFFFAOYSA-N 3h-pyrido[3,2-e][1,4]diazepine Chemical class C1=NCC=NC2=CC=CN=C21 BTQDZLVHRYXJDK-UHFFFAOYSA-N 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000005277 alkyl imino group Chemical group 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- MUXPIKKNIKZVHU-UHFFFAOYSA-N (3-aminopyridin-2-yl)-phenylmethanone Chemical class NC1=CC=CN=C1C(=O)C1=CC=CC=C1 MUXPIKKNIKZVHU-UHFFFAOYSA-N 0.000 abstract 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- VCJCULBSFIZKLM-UHFFFAOYSA-N 1h-pyrido[3,2-c]diazepine Chemical class N1N=CC=CC2=NC=CC=C12 VCJCULBSFIZKLM-UHFFFAOYSA-N 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 239000000164 antipsychotic agent Substances 0.000 abstract 1
- 229940005529 antipsychotics Drugs 0.000 abstract 1
- STAAOWPFPLZYRV-UHFFFAOYSA-N ethyl 2-[(2-benzoyl-6-chloropyridin-3-yl)amino]acetate Chemical compound CCOC(=O)CNC1=CC=C(Cl)N=C1C(=O)C1=CC=CC=C1 STAAOWPFPLZYRV-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- WPQDKLDSEAAFCH-UHFFFAOYSA-N n-(2-benzoyl-6-chloropyridin-3-yl)-2,2,2-trifluoroacetamide Chemical compound FC(F)(F)C(=O)NC1=CC=C(Cl)N=C1C(=O)C1=CC=CC=C1 WPQDKLDSEAAFCH-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1410319 Pyridodiazepines DEUTSCHE GOLDUND SILBERSCHIEDEANSTALT 24 May 1974 [25 May 1973] 23308/74 Heading C2C Compounds of the general formula (n=1-4; R<SP>1</SP>=OH, C 1-6 alkyl or alkoxy, NH 2 , Ph optionally substituted by one or two radicals selected from C 1-6 alkyl and alkoxy, CF 3 , F, Cl; A=O, S, NH, C 1-6 alkylimino or (R<SP>1</SP>=Ph or substituted Ph) two C 1-6 alkoxy groups or a C 2-4 alkylenedioxy group, or CAR<SP>1</SP>=CN; B = O, S, NH, C 1-6 alkylimino; R<SP>2</SP> = H, OH, C 1-6 alkyl or alkoxy, O(CH 2 ) n CAR<SP>1</SP>; N o =N, N#O; R<SP>3,4</SP>=H, F, Cl, CF 3 , C 1-6 alkyl or alkoxy), the corresponding compounds in which the group CBCHR<SP>2</SP> is present in the form CBR<SP>2</SP>=CH, and their salts are prepared by standard methods, e.g. introducing the 1-substituent or ring-closing an appropriately substituted aminopyridophenone. The preparation of 2-benzoyl-3-trifluoroacetamido-6-chloropyridine and 2-benzoyl-3-carbethoxymethylamino-6-chloropyridine is described. The above compounds are psychosedatives, axiolytics, spasmolytics, antipsychotics and antiphlogistic agents, and may be administered in the form of pharmaceutical and veterinary preparations containing them in association with a carrier.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT462873A AT331251B (en) | 1973-05-25 | 1973-05-25 | PROCESS FOR THE PREPARATION OF NEW 6-AZA-7-CHLORO-1,2-DIHYDRO-3H-1,4-BENZODIAZEPINES AND THE SALT THEREOF |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1410319A true GB1410319A (en) | 1975-10-15 |
Family
ID=3566375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2330874A Expired GB1410319A (en) | 1973-05-25 | 1974-05-24 | 6-aza-3h-1,4-benzodiazepines |
Country Status (17)
Country | Link |
---|---|
US (1) | US3900466A (en) |
JP (1) | JPS5019767A (en) |
AR (1) | AR200928A1 (en) |
AT (1) | AT331251B (en) |
BE (1) | BE815467A (en) |
CA (1) | CA1035771A (en) |
CH (1) | CH605942A5 (en) |
DD (1) | DD111206A5 (en) |
DE (1) | DE2425282A1 (en) |
EG (1) | EG11352A (en) |
ES (3) | ES426617A1 (en) |
FR (1) | FR2230367B1 (en) |
GB (1) | GB1410319A (en) |
HU (1) | HU174561B (en) |
NL (1) | NL7407015A (en) |
RO (1) | RO63559A (en) |
ZA (1) | ZA743348B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19710449A1 (en) * | 1997-03-13 | 1998-09-17 | Basf Ag | Process for the purification of sodium hydroxide solution |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3314941A (en) * | 1964-06-23 | 1967-04-18 | American Cyanamid Co | Novel substituted pyridodiazepins |
-
1973
- 1973-05-25 AT AT462873A patent/AT331251B/en not_active IP Right Cessation
-
1974
- 1974-05-08 US US468088A patent/US3900466A/en not_active Expired - Lifetime
- 1974-05-22 AR AR253867A patent/AR200928A1/en active
- 1974-05-22 EG EG188A patent/EG11352A/en active
- 1974-05-22 BE BE6044605A patent/BE815467A/en unknown
- 1974-05-22 FR FR7417836A patent/FR2230367B1/fr not_active Expired
- 1974-05-23 CA CA200,670A patent/CA1035771A/en not_active Expired
- 1974-05-23 DD DD178713A patent/DD111206A5/xx unknown
- 1974-05-24 NL NL7407015A patent/NL7407015A/xx not_active Application Discontinuation
- 1974-05-24 CH CH714474A patent/CH605942A5/xx not_active IP Right Cessation
- 1974-05-24 DE DE19742425282 patent/DE2425282A1/en not_active Withdrawn
- 1974-05-24 ES ES426617A patent/ES426617A1/en not_active Expired
- 1974-05-24 ZA ZA00743348A patent/ZA743348B/en unknown
- 1974-05-24 ES ES426618A patent/ES426618A1/en not_active Expired
- 1974-05-24 ES ES426619A patent/ES426619A1/en not_active Expired
- 1974-05-24 JP JP49058658A patent/JPS5019767A/ja active Pending
- 1974-05-24 HU HU74DE853A patent/HU174561B/en unknown
- 1974-05-24 GB GB2330874A patent/GB1410319A/en not_active Expired
- 1974-05-24 RO RO7400078928A patent/RO63559A/en unknown
Also Published As
Publication number | Publication date |
---|---|
EG11352A (en) | 1977-11-30 |
CH605942A5 (en) | 1978-10-13 |
DD111206A5 (en) | 1975-02-05 |
ATA462873A (en) | 1975-11-15 |
FR2230367A1 (en) | 1974-12-20 |
JPS5019767A (en) | 1975-03-01 |
ES426619A1 (en) | 1977-01-01 |
AR200928A1 (en) | 1974-12-27 |
DE2425282A1 (en) | 1974-12-19 |
US3900466A (en) | 1975-08-19 |
ZA743348B (en) | 1975-05-28 |
BE815467A (en) | 1974-11-22 |
ES426618A1 (en) | 1976-07-01 |
ES426617A1 (en) | 1976-12-16 |
FR2230367B1 (en) | 1978-03-24 |
RO63559A (en) | 1978-07-15 |
HU174561B (en) | 1980-02-28 |
AT331251B (en) | 1976-08-10 |
AU6932574A (en) | 1975-11-27 |
NL7407015A (en) | 1974-11-27 |
CA1035771A (en) | 1978-08-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
694A | Case decided by the comptroller (rule 94(3)/1968) | ||
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |