DE3634763C2 - - Google Patents
Info
- Publication number
- DE3634763C2 DE3634763C2 DE3634763A DE3634763A DE3634763C2 DE 3634763 C2 DE3634763 C2 DE 3634763C2 DE 3634763 A DE3634763 A DE 3634763A DE 3634763 A DE3634763 A DE 3634763A DE 3634763 C2 DE3634763 C2 DE 3634763C2
- Authority
- DE
- Germany
- Prior art keywords
- membrane
- membrane module
- housing
- chamber
- assigned
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000012528 membrane Substances 0.000 claims description 68
- 210000004369 blood Anatomy 0.000 claims description 25
- 239000008280 blood Substances 0.000 claims description 25
- 238000001914 filtration Methods 0.000 claims description 14
- 239000012510 hollow fiber Substances 0.000 claims description 14
- 238000000502 dialysis Methods 0.000 claims description 9
- 239000012466 permeate Substances 0.000 claims description 9
- 238000000746 purification Methods 0.000 claims description 9
- 238000005192 partition Methods 0.000 claims description 5
- 238000004382 potting Methods 0.000 claims description 5
- 230000035699 permeability Effects 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 2
- 238000007373 indentation Methods 0.000 claims description 2
- 238000001746 injection moulding Methods 0.000 claims description 2
- GLVAUDGFNGKCSF-UHFFFAOYSA-N mercaptopurine Chemical compound S=C1NC=NC2=C1NC=N2 GLVAUDGFNGKCSF-UHFFFAOYSA-N 0.000 claims 1
- 239000000706 filtrate Substances 0.000 description 14
- 238000000034 method Methods 0.000 description 11
- 239000007788 liquid Substances 0.000 description 9
- 238000002615 hemofiltration Methods 0.000 description 7
- 230000008030 elimination Effects 0.000 description 6
- 238000003379 elimination reaction Methods 0.000 description 6
- YSUIQYOGTINQIN-UZFYAQMZSA-N 2-amino-9-[(1S,6R,8R,9S,10R,15R,17R,18R)-8-(6-aminopurin-9-yl)-9,18-difluoro-3,12-dihydroxy-3,12-bis(sulfanylidene)-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.2.1.06,10]octadecan-17-yl]-1H-purin-6-one Chemical compound NC1=NC2=C(N=CN2[C@@H]2O[C@@H]3COP(S)(=O)O[C@@H]4[C@@H](COP(S)(=O)O[C@@H]2[C@@H]3F)O[C@H]([C@H]4F)N2C=NC3=C2N=CN=C3N)C(=O)N1 YSUIQYOGTINQIN-UZFYAQMZSA-N 0.000 description 5
- 210000003734 kidney Anatomy 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 239000003792 electrolyte Substances 0.000 description 4
- 238000006467 substitution reaction Methods 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 238000001631 haemodialysis Methods 0.000 description 3
- 230000000322 hemodialysis Effects 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 239000002594 sorbent Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 230000002706 hydrostatic effect Effects 0.000 description 2
- 150000002605 large molecules Chemical class 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 150000003384 small molecules Chemical class 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000001174 ascending effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 230000001447 compensatory effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000008151 electrolyte solution Substances 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000001951 hemoperfusion Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3413—Diafiltration
- A61M1/3417—Diafiltration using distinct filters for dialysis and ultra-filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3482—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate by filtrating the filtrate using another cross-flow filter, e.g. a membrane filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/24—Dialysis ; Membrane extraction
- B01D61/243—Dialysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/58—Multistep processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/04—Hollow fibre modules comprising multiple hollow fibre assemblies
- B01D63/043—Hollow fibre modules comprising multiple hollow fibre assemblies with separate tube sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Water Supply & Treatment (AREA)
- Urology & Nephrology (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863634763 DE3634763A1 (de) | 1986-10-11 | 1986-10-11 | Vorrichtung und verfahren zur blutreinigung |
| EP87114448A EP0264695A3 (de) | 1986-10-11 | 1987-10-03 | Verfahren und Vorrichtung zur Blutreinigung |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863634763 DE3634763A1 (de) | 1986-10-11 | 1986-10-11 | Vorrichtung und verfahren zur blutreinigung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3634763A1 DE3634763A1 (de) | 1988-04-28 |
| DE3634763C2 true DE3634763C2 (en, 2012) | 1989-09-14 |
Family
ID=6311588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19863634763 Granted DE3634763A1 (de) | 1986-10-11 | 1986-10-11 | Vorrichtung und verfahren zur blutreinigung |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP0264695A3 (en, 2012) |
| DE (1) | DE3634763A1 (en, 2012) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19540079A1 (de) * | 1995-10-27 | 1997-04-30 | Joachim Dr Med Boehler | Dialysegerät |
| DE19607162A1 (de) * | 1996-02-26 | 1997-09-04 | Fresenius Ag | Dialysator |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD371439S (en) | 1994-11-15 | 1996-07-02 | Pall Corporation | Multiple compartment cassette |
| EP1466657B1 (en) * | 2003-04-11 | 2012-10-03 | Gambro Lundia AB | Filter device having more than one filtration compartment |
| US20090139930A1 (en) | 2005-10-17 | 2009-06-04 | Jan Sternby | Extracorporeal Blood Cleaning |
| EP2002855B1 (en) | 2007-06-14 | 2012-07-11 | RenApta B.V. | Artificial kidney |
| US9713668B2 (en) * | 2012-01-04 | 2017-07-25 | Medtronic, Inc. | Multi-staged filtration system for blood fluid removal |
| US11154648B2 (en) | 2013-01-09 | 2021-10-26 | Medtronic, Inc. | Fluid circuits for sorbent cartridge with sensors |
| US9713666B2 (en) | 2013-01-09 | 2017-07-25 | Medtronic, Inc. | Recirculating dialysate fluid circuit for blood measurement |
| US9623164B2 (en) | 2013-02-01 | 2017-04-18 | Medtronic, Inc. | Systems and methods for multifunctional volumetric fluid control |
| US10010663B2 (en) | 2013-02-01 | 2018-07-03 | Medtronic, Inc. | Fluid circuit for delivery of renal replacement therapies |
| US10850016B2 (en) | 2013-02-01 | 2020-12-01 | Medtronic, Inc. | Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection |
| US9144640B2 (en) | 2013-02-02 | 2015-09-29 | Medtronic, Inc. | Sorbent cartridge configurations for improved dialysate regeneration |
| US9884145B2 (en) | 2013-11-26 | 2018-02-06 | Medtronic, Inc. | Parallel modules for in-line recharging of sorbents using alternate duty cycles |
| US10052612B2 (en) | 2013-11-26 | 2018-08-21 | Medtronic, Inc. | Zirconium phosphate recharging method and apparatus |
| US10537875B2 (en) | 2013-11-26 | 2020-01-21 | Medtronic, Inc. | Precision recharging of sorbent materials using patient and session data |
| US10016553B2 (en) | 2014-06-24 | 2018-07-10 | Medtronic, Inc. | Replenishing urease in dialysis systems using a urease introducer |
| US10286380B2 (en) | 2014-06-24 | 2019-05-14 | Medtronic, Inc. | Sorbent pouch |
| ES2989503T3 (es) | 2014-06-24 | 2024-11-26 | Mozarc Medical Us Llc | Conjunto modular de regeneración de dialisato |
| EP3160534A4 (en) | 2014-06-24 | 2018-03-07 | Medtronic Inc. | Stacked sorbent assembly |
| CN106659827B (zh) | 2014-06-24 | 2019-07-09 | 美敦力公司 | 使用脲酶袋补充透析系统中的脲酶 |
| WO2015199763A1 (en) | 2014-06-24 | 2015-12-30 | Medtronic, Inc. | A urease introduction system for replenishing urease in a sorbent cartridge |
| US10874787B2 (en) | 2014-12-10 | 2020-12-29 | Medtronic, Inc. | Degassing system for dialysis |
| US9713665B2 (en) | 2014-12-10 | 2017-07-25 | Medtronic, Inc. | Degassing system for dialysis |
| EP3178539A1 (en) * | 2015-12-11 | 2017-06-14 | Gambro Lundia AB | Filter device, system and method for filtration of fluids |
| US10981148B2 (en) | 2016-11-29 | 2021-04-20 | Medtronic, Inc. | Zirconium oxide module conditioning |
| US10960381B2 (en) | 2017-06-15 | 2021-03-30 | Medtronic, Inc. | Zirconium phosphate disinfection recharging and conditioning |
| US11278654B2 (en) | 2017-12-07 | 2022-03-22 | Medtronic, Inc. | Pneumatic manifold for a dialysis system |
| US11033667B2 (en) | 2018-02-02 | 2021-06-15 | Medtronic, Inc. | Sorbent manifold for a dialysis system |
| US11110215B2 (en) | 2018-02-23 | 2021-09-07 | Medtronic, Inc. | Degasser and vent manifolds for dialysis |
| US12285552B2 (en) | 2018-08-14 | 2025-04-29 | Mozarc Medical Us Llc | Precision dialysis therapy based on sorbent effluent analysis |
| US11213616B2 (en) | 2018-08-24 | 2022-01-04 | Medtronic, Inc. | Recharge solution for zirconium phosphate |
| CN109464717B (zh) * | 2018-12-24 | 2024-05-28 | 贝恩医疗设备(广州)有限公司 | 一种用于血液透析体外循环管路的滴口室 |
| US12128165B2 (en) | 2020-04-27 | 2024-10-29 | Mozarc Medical Us Llc | Dual stage degasser |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2447196A1 (fr) * | 1979-01-23 | 1980-08-22 | Sodip Sa | Appareil medical echangeur-separateur a membranes |
| US4350594A (en) * | 1980-04-16 | 1982-09-21 | Kuraray Co., Ltd. | Blood purification using plural ultrafiltration stages |
| DE3326704A1 (de) * | 1983-07-23 | 1985-01-31 | Josef 6902 Sandhausen Magasi | Verfahren und vorrichtung zur haemodialyse |
-
1986
- 1986-10-11 DE DE19863634763 patent/DE3634763A1/de active Granted
-
1987
- 1987-10-03 EP EP87114448A patent/EP0264695A3/de not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19540079A1 (de) * | 1995-10-27 | 1997-04-30 | Joachim Dr Med Boehler | Dialysegerät |
| DE19540079C2 (de) * | 1995-10-27 | 2000-06-21 | Joachim Boehler | Dialysegerät |
| DE19607162A1 (de) * | 1996-02-26 | 1997-09-04 | Fresenius Ag | Dialysator |
| DE19607162C2 (de) * | 1996-02-26 | 1998-01-15 | Fresenius Ag | Verwendung eines Dialysators mit zwei Modulen zur Durchführung eines Verfahrens zum Filtrieren und sofortigen Verwenden von Substituatflüssigkeit in einer Hämodialfiltrationsvorrichtung |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0264695A3 (de) | 1989-02-01 |
| EP0264695A2 (de) | 1988-04-27 |
| DE3634763A1 (de) | 1988-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |