DE3575135D1 - Substituierte benzylphthalazinon-derivate. - Google Patents

Substituierte benzylphthalazinon-derivate.

Info

Publication number
DE3575135D1
DE3575135D1 DE8585108760T DE3575135T DE3575135D1 DE 3575135 D1 DE3575135 D1 DE 3575135D1 DE 8585108760 T DE8585108760 T DE 8585108760T DE 3575135 T DE3575135 T DE 3575135T DE 3575135 D1 DE3575135 D1 DE 3575135D1
Authority
DE
Germany
Prior art keywords
substituted
group
benzylphthalazinone
derivatives
benzylphthalazinone derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585108760T
Other languages
German (de)
English (en)
Inventor
Juergen Dr Engel
Gerhard Dr Scheffler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Pharma AG filed Critical Asta Pharma AG
Priority to DE8585108760T priority Critical patent/DE3575135D1/de
Application granted granted Critical
Publication of DE3575135D1 publication Critical patent/DE3575135D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8585108760T 1984-09-14 1985-07-12 Substituierte benzylphthalazinon-derivate. Expired - Lifetime DE3575135D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE8585108760T DE3575135D1 (de) 1984-09-14 1985-07-12 Substituierte benzylphthalazinon-derivate.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3433776 1984-09-14
DE8585108760T DE3575135D1 (de) 1984-09-14 1985-07-12 Substituierte benzylphthalazinon-derivate.

Publications (1)

Publication Number Publication Date
DE3575135D1 true DE3575135D1 (de) 1990-02-08

Family

ID=6245402

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585108760T Expired - Lifetime DE3575135D1 (de) 1984-09-14 1985-07-12 Substituierte benzylphthalazinon-derivate.

Country Status (16)

Country Link
US (1) US4704387A (cg-RX-API-DMAC10.html)
EP (1) EP0174464B1 (cg-RX-API-DMAC10.html)
JP (1) JPH0699425B2 (cg-RX-API-DMAC10.html)
AT (1) ATE49205T1 (cg-RX-API-DMAC10.html)
CA (1) CA1263652A (cg-RX-API-DMAC10.html)
DD (1) DD240205A5 (cg-RX-API-DMAC10.html)
DE (1) DE3575135D1 (cg-RX-API-DMAC10.html)
DK (1) DK167118B1 (cg-RX-API-DMAC10.html)
ES (2) ES8605510A1 (cg-RX-API-DMAC10.html)
GR (1) GR852219B (cg-RX-API-DMAC10.html)
HU (1) HU197740B (cg-RX-API-DMAC10.html)
IE (1) IE64839B1 (cg-RX-API-DMAC10.html)
IL (1) IL75989A0 (cg-RX-API-DMAC10.html)
MX (1) MX159034A (cg-RX-API-DMAC10.html)
PT (1) PT81122B (cg-RX-API-DMAC10.html)
ZA (1) ZA856524B (cg-RX-API-DMAC10.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3677322D1 (de) * 1985-11-11 1991-03-07 Asta Pharma Ag 4-benzyl-1-(2h)-phthalazinon-derivate.
EP0289939A1 (de) * 1987-05-08 1988-11-09 ASTA Pharma AG Neue 4-Benzyl-1-(2H)-phthalazinon-Derivate mit einem Aminosäurerest
US5232919A (en) * 1987-11-13 1993-08-03 Asta Pharma Aktiengesellschaft Azelastine embonate and compositions which contain it
DE3877904D1 (de) * 1987-11-13 1993-03-11 Asta Pharma Ag Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge.
MC2025A1 (fr) * 1988-04-20 1990-04-25 Asta Pharma Ag Medicament contenant de l'azelastine et capable de liberer celle-ci de facon controlee
US5271946A (en) * 1988-04-20 1993-12-21 Asta Pharma Aktiengesellschaft Controlled release azelastine-containing pharmaceutical compositions
EP0396069B1 (de) * 1989-05-05 1994-06-22 ASTA Medica Aktiengesellschaft Salze des Azelastins mit verbesserter Löslichkeit
JPH04198180A (ja) * 1990-11-28 1992-07-17 Eezai Kagaku Kk ベンジルフタラゾン誘導体の製造方法
DE4207234A1 (de) * 1992-03-07 1993-09-09 Asta Medica Ag Neue aminocarbonsaeure-derivate mit antiallergischer/antiasthmatischer wirkung und verfahren zu deren herstellung
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
BRPI0517891A (pt) 2004-11-24 2008-10-21 Medpointe Healthcare Inc composições compreendendo azelastina e métodos de uso das mesmas
TW200811116A (en) * 2006-04-20 2008-03-01 Glaxo Group Ltd Compounds
JP2011500537A (ja) * 2007-10-11 2011-01-06 グラクソ グループ リミテッド Ｈ１受容体アンタゴニストとしてのフタラジンおよびピリド［３，４−ｄ］ピリダジン化合物
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
CH572914A5 (cg-RX-API-DMAC10.html) * 1971-01-22 1976-02-27 Asta Werke Ag Chem Fab
DE2114884A1 (de) * 1971-03-27 1972-10-12 Cassella Farbwerke Mainkur Ag, 6000 Frankfurt Basisch substituierte Derivate des 1(2H)-Phthalazinons
US3813384A (en) * 1972-01-17 1974-05-28 Asta Werke Ag Chem Fab Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof
US4665181A (en) * 1984-05-17 1987-05-12 Pennwalt Corporation Anti-inflammatory phthalazinones

Also Published As

Publication number Publication date
JPS6172782A (ja) 1986-04-14
EP0174464A2 (de) 1986-03-19
PT81122A (de) 1985-10-01
IL75989A0 (en) 1985-12-31
US4704387A (en) 1987-11-03
ES546959A0 (es) 1986-03-16
IE852270L (en) 1986-03-14
ES8605509A1 (es) 1986-03-16
PT81122B (pt) 1988-01-22
DK416585D0 (da) 1985-09-13
MX159034A (es) 1989-04-13
GR852219B (cg-RX-API-DMAC10.html) 1986-01-14
ZA856524B (en) 1986-04-30
HUT38340A (en) 1986-05-28
DD240205A5 (de) 1986-10-22
ATE49205T1 (de) 1990-01-15
JPH0699425B2 (ja) 1994-12-07
CA1263652A (en) 1989-12-05
EP0174464A3 (en) 1986-12-30
DK416585A (da) 1986-03-15
ES546971A0 (es) 1986-03-16
EP0174464B1 (de) 1990-01-03
ES8605510A1 (es) 1986-03-16
IE64839B1 (en) 1995-09-06
DK167118B1 (da) 1993-08-30
HU197740B (en) 1989-05-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ASTA MEDICA AG, 6000 FRANKFURT, DE

8327 Change in the person/name/address of the patent owner

Owner name: ASTA MEDICA AG, O-8020 DRESDEN, DE

8339 Ceased/non-payment of the annual fee