DE3529478A1 - 7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung - Google Patents

7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung

Info

Publication number
DE3529478A1
DE3529478A1 DE19853529478 DE3529478A DE3529478A1 DE 3529478 A1 DE3529478 A1 DE 3529478A1 DE 19853529478 DE19853529478 DE 19853529478 DE 3529478 A DE3529478 A DE 3529478A DE 3529478 A1 DE3529478 A1 DE 3529478A1
Authority
DE
Germany
Prior art keywords
desaza
nucleotides
deoxyguanosine
monophosphate
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19853529478
Other languages
German (de)
English (en)
Inventor
Frank Prof Seela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6278727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3529478(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to DE19853529478 priority Critical patent/DE3529478A1/de
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to ES8601028A priority patent/ES2002653A6/es
Priority to DE8686111117T priority patent/DE3674861D1/de
Priority to EP86111117A priority patent/EP0212536B1/de
Priority to AT86111117T priority patent/ATE57383T1/de
Priority to US06/896,657 priority patent/US4804748A/en
Priority to JP61190699A priority patent/JPS6245596A/ja
Publication of DE3529478A1 publication Critical patent/DE3529478A1/de
Priority to US07/269,999 priority patent/US5480980A/en
Priority to US08/858,054 priority patent/US5990303A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE19853529478 1985-08-16 1985-08-16 7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung Withdrawn DE3529478A1 (de)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DE19853529478 DE3529478A1 (de) 1985-08-16 1985-08-16 7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung
ES8601028A ES2002653A6 (es) 1985-08-16 1986-08-12 Procedimiento para la preparacion de 7-desaza-2'-desoxiguanosin-nucleotidos.
DE8686111117T DE3674861D1 (de) 1985-08-16 1986-08-12 7-desaza-2'-desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung.
EP86111117A EP0212536B1 (de) 1985-08-16 1986-08-12 7-Desaza-2'-desoxyguanosin-nukleotide, Verfahren zu deren Herstellung und deren Verwendung zur Nukleinsäure-Sequenzierung
AT86111117T ATE57383T1 (de) 1985-08-16 1986-08-12 7-desaza-2'-desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung.
US06/896,657 US4804748A (en) 1985-08-16 1986-08-13 7-deaza-2'-deoxyguanosine nucleotides
JP61190699A JPS6245596A (ja) 1985-08-16 1986-08-15 ７−デスアザ−２′−デスオキシグアノシン−ヌクレオチド、その製法
US07/269,999 US5480980A (en) 1985-08-16 1988-11-14 7-Deaza-2'-deoxyguanosine nucleotides and nucleic acids analogs thereof
US08/858,054 US5990303A (en) 1985-08-16 1997-05-16 Synthesis of 7-deaza-2'deoxyguanosine nucleotides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853529478 DE3529478A1 (de) 1985-08-16 1985-08-16 7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung

Publications (1)

Publication Number Publication Date
DE3529478A1 true DE3529478A1 (de) 1987-02-19

Family

ID=6278727

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19853529478 Withdrawn DE3529478A1 (de) 1985-08-16 1985-08-16 7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung
DE8686111117T Expired - Lifetime DE3674861D1 (de) 1985-08-16 1986-08-12 7-desaza-2'-desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8686111117T Expired - Lifetime DE3674861D1 (de) 1985-08-16 1986-08-12 7-desaza-2'-desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung.

Country Status (6)

Country Link
US (3) US4804748A (https=)
EP (1) EP0212536B1 (https=)
JP (1) JPS6245596A (https=)
AT (1) ATE57383T1 (https=)
DE (2) DE3529478A1 (https=)
ES (1) ES2002653A6 (https=)

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US6054442A (en) * 1995-07-06 2000-04-25 Board Of Regents, University Of Texas System Methods and compositions for modulation and inhibition of telomerase in vitro
US6150510A (en) * 1995-11-06 2000-11-21 Aventis Pharma Deutschland Gmbh Modified oligonucleotides, their preparation and their use

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EP0710667A3 (de) * 1994-11-04 1997-09-10 Hoechst Ag Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung
US5844106A (en) * 1994-11-04 1998-12-01 Hoechst Aktiengesellschaft Modified oligonucleotides, their preparation and their use
US6479651B1 (en) 1994-11-04 2002-11-12 Aventis Pharma Deutschland Gmbh Modified oligonucleotides, their preparation and their use
US6987177B2 (en) 1994-11-04 2006-01-17 Aventis Pharma Deutschland Gmbh Modified oligonucleotides, their preparation and their use
US6004939A (en) * 1995-07-06 1999-12-21 Ctrc Research Foundation Board Of Regents Methods for modulation and inhibition of telomerase
US6054442A (en) * 1995-07-06 2000-04-25 Board Of Regents, University Of Texas System Methods and compositions for modulation and inhibition of telomerase in vitro
US6593306B1 (en) * 1995-07-06 2003-07-15 Board Of Regents, The University Of Texas Systems Methods for modulation and inhibition of telomerase
US6150510A (en) * 1995-11-06 2000-11-21 Aventis Pharma Deutschland Gmbh Modified oligonucleotides, their preparation and their use

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EP0212536B1 (de) 1990-10-10
DE3674861D1 (de) 1990-11-15
US4804748A (en) 1989-02-14
EP0212536A2 (de) 1987-03-04
US5990303A (en) 1999-11-23
EP0212536A3 (en) 1988-03-16
JPS6245596A (ja) 1987-02-27
JPS638120B2 (https=) 1988-02-19
ATE57383T1 (de) 1990-10-15
US5480980A (en) 1996-01-02
ES2002653A6 (es) 1988-09-16

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