DE3508356C2 - - Google Patents

Info

Publication number
DE3508356C2
DE3508356C2 DE3508356A DE3508356A DE3508356C2 DE 3508356 C2 DE3508356 C2 DE 3508356C2 DE 3508356 A DE3508356 A DE 3508356A DE 3508356 A DE3508356 A DE 3508356A DE 3508356 C2 DE3508356 C2 DE 3508356C2
Authority
DE
Germany
Prior art keywords
group
general formula
acetylneuraminic acid
chromatography
acetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3508356A
Other languages
German (de)
English (en)
Other versions
DE3508356A1 (de
Inventor
Haruo Matsudo Chiba Jp Ogura
Kimio Furuhata
Toshiaki Osawa
Satoshi Tokio/Tokyo Jp Toyoshima
Yoshiyasu Musashino Tokio/Tokyo Jp Shitori
Masayoshi Kunitachi Tokio/Tokyo Jp Ito
Shoji Iruma Saitama Jp Yoshimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mect Corp
Original Assignee
Mect Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mect Corp filed Critical Mect Corp
Publication of DE3508356A1 publication Critical patent/DE3508356A1/de
Application granted granted Critical
Publication of DE3508356C2 publication Critical patent/DE3508356C2/de
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
DE19853508356 1984-03-09 1985-03-08 Sialinsaeure-derivate und verfahren zu ihrer herstellung Granted DE3508356A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59044906A JPS60190791A (ja) 1984-03-09 1984-03-09 シアル酸誘導体およびその製造法

Publications (2)

Publication Number Publication Date
DE3508356A1 DE3508356A1 (de) 1985-09-12
DE3508356C2 true DE3508356C2 (US07608600-20091027-C00048.png) 1988-11-17

Family

ID=12704508

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19853508356 Granted DE3508356A1 (de) 1984-03-09 1985-03-08 Sialinsaeure-derivate und verfahren zu ihrer herstellung

Country Status (7)

Country Link
US (1) US4691012A (US07608600-20091027-C00048.png)
JP (1) JPS60190791A (US07608600-20091027-C00048.png)
CA (1) CA1257257A (US07608600-20091027-C00048.png)
DE (1) DE3508356A1 (US07608600-20091027-C00048.png)
FR (1) FR2560881B1 (US07608600-20091027-C00048.png)
GB (1) GB2158433B (US07608600-20091027-C00048.png)
HK (1) HK27689A (US07608600-20091027-C00048.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6287598A (ja) * 1985-10-11 1987-04-22 Mect Corp N−グリコリルノイラミン酸誘導体
CA1262130A (en) * 1985-10-11 1989-10-03 Shoji Yoshimura Process for preparing n-glycolylneuraminic acid derivatives
ES2058070T3 (es) * 1986-05-09 1994-11-01 Pulverer Gerhard Utilizacion de monosacaridos especificos para la preparacion de un medicamento para impedir metastasis de tumores malignos.
WO1987006936A1 (en) * 1986-05-12 1987-11-19 Mect Corporation Sialosylcholesterol, process for its preparation, and drug for treating diseases of nervous system
JPH0276892A (ja) * 1988-06-16 1990-03-16 Toshio Goto 3−フェニルチオシアル酸誘導体、その製造方法、シアル酸含有オリゴ糖誘導体およびその製造方法
HU205089B (en) * 1989-05-31 1992-03-30 Biogal Gyogyszergyar Process for producing new thymine derivatives and pharmaceutical compositions comprising same
US5138044A (en) * 1990-08-13 1992-08-11 Glycomed, Inc. Synthesis of sialosides
US5438125A (en) * 1991-03-06 1995-08-01 Nippon Zoki Pharmaceutical Co., Ltd. Sialic acid derivatives
JPH0591854U (ja) * 1992-05-20 1993-12-14 アルプス電気株式会社 サ−マルヘッドのクリ−ニング装置
KR19980703698A (ko) * 1996-02-08 1998-12-05 모리따 겐조 암 전이 억제 항암제 물질

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3501456A (en) * 1967-08-08 1970-03-17 Merck & Co Inc Arabinofuranosyl nucleosides and intermediates
DE3249916C2 (US07608600-20091027-C00048.png) * 1981-05-22 1992-04-02 Mect Corp., Tokio/Tokyo, Jp
JPS6019917B2 (ja) * 1981-05-22 1985-05-18 関東医師製薬株式会社 N―アセチルノイラミン酸誘導体

Also Published As

Publication number Publication date
FR2560881A1 (fr) 1985-09-13
FR2560881B1 (fr) 1988-11-25
DE3508356A1 (de) 1985-09-12
GB8506244D0 (en) 1985-04-11
US4691012A (en) 1987-09-01
GB2158433A (en) 1985-11-13
CA1257257A (en) 1989-07-11
JPS637556B2 (US07608600-20091027-C00048.png) 1988-02-17
JPS60190791A (ja) 1985-09-28
HK27689A (en) 1989-04-07
GB2158433B (en) 1987-05-13

Similar Documents

Publication Publication Date Title
DE3609052C2 (de) Anthracyclinglykoside, Verfahren zu ihrer Herstellung und sie enthaltende Zubereitungen
DE2618822C3 (de) Anthracyclin-Glycoside und Verfahren zu deren Herstellung
DE3129112C2 (US07608600-20091027-C00048.png)
DD216468A5 (de) Verfahren zur herstellung von nucleosiden
DE2510866A1 (de) Adriamycine und verfahren zu deren herstellung
CH622529A5 (en) Process for the preparation of anthracycline glycosides and optically active anthracyclinones
DE3508356C2 (US07608600-20091027-C00048.png)
DE3044740C2 (US07608600-20091027-C00048.png)
EP0021231B1 (de) Verfahren zur Herstellung von 5'-Deoxy-5-fluoruridin und Zwischenprodukte in diesem Verfahren
CH500203A (de) Verfahren zur Herstellung von Nucleosiden
DE3390162T1 (de) Desoxyuridinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika
DD294947A5 (de) Verfahren zur herstellung von acylierten epipodophyllotoxinderivaten
EP0270992A2 (de) Zytostatisch wirksame Anthracyclinderivate
DE3219209A1 (de) N-acetylneuraminsaeure-derivate
DE3719377C2 (de) Anthracyclinglykoside, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
DE2511828C2 (US07608600-20091027-C00048.png)
DE2517293C2 (de) Neue Cardenolid-β-Glykoside, ihre Herstellung und Verwendung
DE2532069A1 (de) Acylierte pyrazofurinderivate und verfahren zu ihrer herstellung
DE3317702C2 (US07608600-20091027-C00048.png)
DE2817923C2 (de) Septacidinverbindungen und diese enthaltende Arzneimittel
DE3913326A1 (de) Verfahren zur herstellung von etoposiden
Salo et al. Selective cleavage of the glycosidic bond in acetylated 2-acetamido-2-deoxy-. beta.-D-glucopyranosides by a chemical transglycosylation
DE2249397A1 (de) Adenosinester und -aether
EP0277310A1 (de) Zytostatisch wirksame Anthracyclinderivate
CH627478A5 (de) Verfahren zur herstellung von doxorubicinthioestern.

Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8127 New person/name/address of the applicant

Owner name: MECT CORP., TOKIO/TOKYO, JP

D2 Grant after examination
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: VOSSIUS, V., DIPL.-CHEM. DR.RER.NAT. TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D., DIPL.-PHYS. DR.RER.NAT. RAUH, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 8000 MUENCHEN

8328 Change in the person/name/address of the agent

Free format text: TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D., DIPL.-PHYS. DR.RER.NAT. RAUH, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee