DE3481369D1 - Allopurinol proheilmittel. - Google Patents

Allopurinol proheilmittel.

Info

Publication number
DE3481369D1
DE3481369D1 DE8484902508T DE3481369T DE3481369D1 DE 3481369 D1 DE3481369 D1 DE 3481369D1 DE 8484902508 T DE8484902508 T DE 8484902508T DE 3481369 T DE3481369 T DE 3481369T DE 3481369 D1 DE3481369 D1 DE 3481369D1
Authority
DE
Germany
Prior art keywords
proheilmittel
allopurinol
allopurinol proheilmittel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484902508T
Other languages
English (en)
Inventor
Hans Bundgaard
Erik Falch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexal AS
Original Assignee
GEA Farmaceutisk Fabrik AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GEA Farmaceutisk Fabrik AS filed Critical GEA Farmaceutisk Fabrik AS
Application granted granted Critical
Publication of DE3481369D1 publication Critical patent/DE3481369D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8484902508T 1983-06-30 1984-06-19 Allopurinol proheilmittel. Expired - Lifetime DE3481369D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK3028/83A DK302883D0 (da) 1983-06-30 1983-06-30 Allopurinol prodrugs
PCT/DK1984/000057 WO1985000368A1 (en) 1983-06-30 1984-06-19 Allopurinol prodrugs

Publications (1)

Publication Number Publication Date
DE3481369D1 true DE3481369D1 (en) 1990-03-22

Family

ID=8118314

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484902508T Expired - Lifetime DE3481369D1 (en) 1983-06-30 1984-06-19 Allopurinol proheilmittel.

Country Status (10)

Country Link
US (1) US4694006A (de)
EP (1) EP0148883B1 (de)
JP (1) JPS60501708A (de)
DE (1) DE3481369D1 (de)
DK (1) DK302883D0 (de)
ES (1) ES8600293A1 (de)
FI (1) FI83221C (de)
IE (1) IE57696B1 (de)
IT (1) IT1214854B (de)
WO (1) WO1985000368A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943579A (en) * 1987-10-06 1990-07-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble prodrugs of camptothecin
IT1244501B (it) * 1991-03-22 1994-07-15 Sigma Tau Ind Farmaceuti Derivati amminoacilici e oligopeptidici dell'allopurinolo dotati di attivita' immunostimolante e composizioni farmaceutiche che li contengono
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
US7671029B2 (en) * 1999-08-06 2010-03-02 Immupharma Sa Compositions and methods for enhanced pharmacological activity of compositions comprising peptide drug substances
US6908900B2 (en) * 2001-01-17 2005-06-21 Zimmer & Associates Ag Compositions and methods for enhanced pharmacological activity through oral and parenteral administration of compositions comprising polypeptide drug substances and other poorly absorbed active ingredients
WO2003020321A2 (en) * 2001-09-06 2003-03-13 Zimmer Robert H Derivatives of pseudo-peptides, their preparation and their biological uses
WO2004043396A2 (en) * 2002-11-09 2004-05-27 Nobex Corporation Modified carbamate-containing prodrugs and methods of synthesizing same
ES2885698T3 (es) 2009-06-25 2021-12-15 Alkermes Pharma Ireland Ltd Profármacos de compuestos nh-ácidos
ES2691671T3 (es) 2010-06-24 2018-11-28 Alkermes Pharma Ireland Limited Profármacos de compuestos NH-acídicos: derivados de éster, carbonato, carbamato y fosfonato
EP2685979B1 (de) 2011-03-18 2016-08-24 Alkermes Pharma Ireland Limited Injizierbare pharmazeutische zusammensetzungen enthaltend wasserunlösliches antipsychotisches, sorbitanlaurat und polysorbat 20
ES2715562T3 (es) 2011-12-15 2019-06-04 Alkermes Pharma Ireland Ltd Profármacos de compuestos de amina secundaria
JP6219918B2 (ja) 2012-03-19 2017-10-25 アルカームス ファーマ アイルランド リミテッド グリセロールエステルを含む医薬組成物
WO2013142198A1 (en) 2012-03-19 2013-09-26 Alkermes Pharma Ireland Limited Pharmaaceutical compositions comprising fatty acid esters
EP2827866B1 (de) 2012-03-19 2023-05-03 Alkermes Pharma Ireland Limited Pharmazeutische zusammensetzungen mit benzylalkohol
WO2014080285A2 (en) 2012-09-19 2014-05-30 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
US8883857B2 (en) * 2012-12-07 2014-11-11 Baylor College Of Medicine Small molecule xanthine oxidase inhibitors and methods of use
US9452131B2 (en) 2014-03-20 2016-09-27 Alkermes Pharma Ireland Limited Aripiprazole formulations having increased injection speeds
WO2016015177A1 (zh) * 2014-06-23 2016-02-04 北京新天宇科技开发有限公司 吡唑并[3，4-d]嘧啶-4-酮衍生物、其制备方法和应用
CN105272984B (zh) * 2014-06-23 2019-06-14 湘北威尔曼制药股份有限公司 吡唑并[3,4-d]嘧啶-4-酮衍生物、其制备方法和应用
CN112423754A (zh) 2018-03-05 2021-02-26 奥克梅斯制药爱尔兰有限公司 阿立哌唑的给药策略

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2868803A (en) * 1956-02-10 1959-01-13 Ciba Pharm Prod Inc New pyrazoles and method of preparing same
US3474098A (en) * 1968-08-22 1969-10-21 Burroughs Wellcome Co Pyrazolo-(3,4-d) pyrimidines
GB1339748A (en) * 1970-07-02 1973-12-05 Ici Ltd Pyrimidine derivatives
DK172081A (da) * 1980-04-21 1981-10-22 Merck & Co Inc Mercaptoforbindelse og fremgangsmaade til fremstilling deraf
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
US4565868A (en) * 1983-02-07 1986-01-21 Syntex (U.S.A.) Inc. Process for preparing guanine derivatives
US4555579A (en) * 1983-03-24 1985-11-26 E. R. Squibb & Sons, Inc. Dioxolenylmethyl ester prodrugs of phosphinic acid ace inhibitors

Also Published As

Publication number Publication date
JPS60501708A (ja) 1985-10-11
EP0148883B1 (de) 1990-02-14
WO1985000368A1 (en) 1985-01-31
FI850829L (fi) 1985-02-28
IE57696B1 (en) 1993-03-10
IE841659L (en) 1984-12-30
IT1214854B (it) 1990-01-18
FI850829A0 (fi) 1985-02-28
US4694006A (en) 1987-09-15
DK302883D0 (da) 1983-06-30
EP0148883A1 (de) 1985-07-24
IT8467669A0 (it) 1984-06-29
ES533873A0 (es) 1985-10-01
FI83221B (fi) 1991-02-28
ES8600293A1 (es) 1985-10-01
FI83221C (fi) 1991-06-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee