DE3463655D1 - Triazole antifungal agents - Google Patents

Triazole antifungal agents

Info

Publication number
DE3463655D1
DE3463655D1 DE8484301013T DE3463655T DE3463655D1 DE 3463655 D1 DE3463655 D1 DE 3463655D1 DE 8484301013 T DE8484301013 T DE 8484301013T DE 3463655 T DE3463655 T DE 3463655T DE 3463655 D1 DE3463655 D1 DE 3463655D1
Authority
DE
Germany
Prior art keywords
antifungal agents
triazole antifungal
triazole
agents
antifungal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484301013T
Other languages
English (en)
Inventor
Kenneth Dr Richardson
Geoffrey Edward Dr Gymer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Pfizer Corp
Original Assignee
Pfizer Ltd
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd, Pfizer Corp filed Critical Pfizer Ltd
Application granted granted Critical
Publication of DE3463655D1 publication Critical patent/DE3463655D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647Triazoles; Hydrogenated triazoles
    • A01N43/6531,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8484301013T 1983-02-25 1984-02-16 Triazole antifungal agents Expired DE3463655D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838305377A GB8305377D0 (en) 1983-02-25 1983-02-25 Antifungal agents

Publications (1)

Publication Number Publication Date
DE3463655D1 true DE3463655D1 (en) 1987-06-19

Family

ID=10538659

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484301013T Expired DE3463655D1 (en) 1983-02-25 1984-02-16 Triazole antifungal agents

Country Status (28)

Country Link
US (1) US4960782A (de)
EP (1) EP0118245B1 (de)
JP (1) JPS59193877A (de)
KR (1) KR870000356B1 (de)
AU (1) AU545660B2 (de)
CA (1) CA1257276A (de)
CS (1) CS241047B2 (de)
DD (1) DD216457A5 (de)
DE (1) DE3463655D1 (de)
DK (2) DK160823C (de)
ES (1) ES8506653A1 (de)
FI (1) FI80683C (de)
GB (1) GB8305377D0 (de)
GR (1) GR79816B (de)
HK (1) HK32389A (de)
HU (1) HU190545B (de)
IE (1) IE57056B1 (de)
IL (1) IL71042A (de)
IN (1) IN161372B (de)
NO (1) NO161559C (de)
NZ (1) NZ207256A (de)
PH (1) PH20060A (de)
PL (1) PL142674B1 (de)
PT (1) PT78128B (de)
SG (1) SG6589G (de)
SU (1) SU1405701A3 (de)
YU (1) YU42634B (de)
ZA (1) ZA841322B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0117100B1 (de) * 1983-02-16 1986-12-10 Pfizer Limited Triazol enthaltende Fungizide
EP0149426B1 (de) * 1983-12-20 1988-05-04 Ciba-Geigy Ag Mikrobizide
IE58738B1 (en) * 1984-09-05 1993-11-03 Ici Plc Antifungal azole compounds
EP0228995A1 (de) * 1985-12-20 1987-07-15 Ciba-Geigy Ag Mikrobizide
DE3825841A1 (de) * 1988-07-29 1990-02-01 Basf Ag 1-halogen-1-azolypropene und -methyloxirane und diese enthaltende fungizide
FR2661176B1 (fr) * 1990-04-20 1992-06-12 Adir Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive.
DE4034352A1 (de) * 1990-10-29 1992-04-30 Basf Ag 1-halogen-1-azolylmethanderivate und diese enthaltende fungizide
TW210334B (de) * 1990-12-12 1993-08-01 Ciba Geigy Ag
US5488035A (en) * 1991-12-06 1996-01-30 Pioneer Hi-Bred International, Inc. Peptide with inhibitory activity towards plant pathogenic fungi
JP3471831B2 (ja) * 1991-12-09 2003-12-02 富山化学工業株式会社 新規なトリアゾール誘導体およびその塩
US5360612A (en) * 1992-10-13 1994-11-01 Pfizer Inc. Pharmaceutical compositions containing triazole derivatives for rectal administration
CA2838916C (en) 2011-06-23 2020-08-11 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
ES2774267T3 (es) 2012-01-20 2020-07-20 Mycovia Pharmaceuticals Inc Compuestos inhibidores de metaloenzimas
TWI646088B (zh) * 2012-03-16 2019-01-01 維愛美製藥公司 金屬酶抑制劑化合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2918894A1 (de) * 1979-05-10 1980-11-20 Bayer Ag Fluorierte 1-triazolyl-butan-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
DE2938534A1 (de) * 1979-09-24 1981-04-23 Bayer Ag, 5090 Leverkusen Acylierte triazolyl-(gamma)-fluorpinakolyl-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
DE3033592A1 (de) * 1980-09-06 1982-04-22 Bayer Ag, 5090 Leverkusen Fluorierte 1-azolyl-butan-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
EP0069442B1 (de) * 1981-06-06 1985-02-20 Pfizer Limited Fungizide Mittel, Verfahren zu deren Herstellung, und diese enthaltende pharmazeutische Zusammenstellungen
DE3210570A1 (de) * 1982-03-23 1983-10-06 Hoechst Ag 3-azolyl-1,2-diaryl-1-halogen-1-propene, ihre herstellung, ihre verwendung als pflanzenschutzmittel und diese verbindungen enthaltende praeparate
GR79307B (de) * 1982-06-09 1984-10-22 Pfizer
US4510148A (en) * 1982-06-12 1985-04-09 Pfizer Inc. 2-Heterocyclic-1,3-bis(1H-1,2,4-triazol-1-yl)-propan-2-ols as antifungal agents
US4518604A (en) * 1983-07-25 1985-05-21 Pfizer Inc. Antifungal 1-aryl-2-(1H-1,2,4-triazol-1yl)-1-perfluoroalkylethyl halides
EP0149426B1 (de) * 1983-12-20 1988-05-04 Ciba-Geigy Ag Mikrobizide

Also Published As

Publication number Publication date
IN161372B (de) 1987-11-21
AU2504084A (en) 1984-08-30
AU545660B2 (en) 1985-07-25
JPS6411631B2 (de) 1989-02-27
PH20060A (en) 1986-09-18
PT78128A (en) 1984-03-01
PL142674B1 (en) 1987-11-30
FI840764A0 (fi) 1984-02-24
HU190545B (en) 1986-09-29
PT78128B (en) 1986-07-17
DD216457A5 (de) 1984-12-12
HUT34012A (en) 1985-01-28
IL71042A0 (en) 1984-05-31
ZA841322B (en) 1985-10-30
DK369889D0 (da) 1989-07-27
IE840451L (en) 1984-08-25
CS241047B2 (en) 1986-03-13
SG6589G (en) 1989-06-09
DK171233B1 (da) 1996-08-05
FI840764A (fi) 1984-08-26
NO840721L (no) 1984-08-27
GR79816B (de) 1984-10-31
DK97884A (da) 1984-08-26
EP0118245B1 (de) 1987-05-13
US4960782A (en) 1990-10-02
DK97884D0 (da) 1984-02-24
DK160823C (da) 1991-10-07
NZ207256A (en) 1986-07-11
PL246356A1 (en) 1985-02-27
DK369889A (da) 1989-07-27
YU42634B (en) 1988-10-31
SU1405701A3 (ru) 1988-06-23
IL71042A (en) 1987-07-31
NO161559B (no) 1989-05-22
ES529992A0 (es) 1985-07-16
NO161559C (no) 1989-08-30
EP0118245A1 (de) 1984-09-12
KR870000356B1 (ko) 1987-03-05
JPS59193877A (ja) 1984-11-02
HK32389A (en) 1989-04-28
DK160823B (da) 1991-04-22
FI80683C (fi) 1990-07-10
KR840008018A (ko) 1984-12-12
YU33584A (en) 1986-08-31
FI80683B (fi) 1990-03-30
CA1257276A (en) 1989-07-11
IE57056B1 (en) 1992-04-08
CS127684A2 (en) 1985-06-13
ES8506653A1 (es) 1985-07-16
GB8305377D0 (en) 1983-03-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee