DE3422411A1 - Spirosuccinimide, ihre herstellung und verwendung - Google Patents

Spirosuccinimide, ihre herstellung und verwendung

Info

Publication number
DE3422411A1
DE3422411A1 DE3422411A DE3422411A DE3422411A1 DE 3422411 A1 DE3422411 A1 DE 3422411A1 DE 3422411 A DE3422411 A DE 3422411A DE 3422411 A DE3422411 A DE 3422411A DE 3422411 A1 DE3422411 A1 DE 3422411A1
Authority
DE
Germany
Prior art keywords
carbon atoms
alkyl
formula
compounds
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE3422411A
Other languages
German (de)
English (en)
Inventor
Georg Dr. Binningen Bolliger
Erhard Dr. Schenker
René Dr. Basel Spiegel
Hans Dr. Binningen Weidmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Sandoz Patent GmbH
Original Assignee
Sandoz AG
Sandoz Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG, Sandoz Patent GmbH filed Critical Sandoz AG
Publication of DE3422411A1 publication Critical patent/DE3422411A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE3422411A 1983-06-27 1984-06-16 Spirosuccinimide, ihre herstellung und verwendung Withdrawn DE3422411A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH350383 1983-06-27
CH350583 1983-06-27
CH350483 1983-06-27

Publications (1)

Publication Number Publication Date
DE3422411A1 true DE3422411A1 (de) 1985-01-03

Family

ID=27174377

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3422411A Withdrawn DE3422411A1 (de) 1983-06-27 1984-06-16 Spirosuccinimide, ihre herstellung und verwendung

Country Status (16)

Country Link
AU (1) AU2983384A (nl)
DE (1) DE3422411A1 (nl)
DK (1) DK310184A (nl)
ES (1) ES8601202A1 (nl)
FI (1) FI842547A (nl)
FR (1) FR2549061A1 (nl)
GB (1) GB2142332A (nl)
GR (1) GR82274B (nl)
HU (1) HUT36793A (nl)
IL (1) IL72218A0 (nl)
IT (1) IT1199148B (nl)
LU (1) LU85434A1 (nl)
NL (1) NL8401907A (nl)
PT (1) PT78787B (nl)
SE (1) SE8403376L (nl)
WO (1) WO1985000171A1 (nl)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172526A1 (de) * 1984-08-24 1986-02-26 Troponwerke GmbH & Co. KG Neue Benzodiazepine, Verfahren zu ihrer Herstellung sowie ihre Verwendung
EP0464846A1 (en) * 1990-07-06 1992-01-08 Sumitomo Pharmaceuticals Company, Limited Imide derivatives, and their production and use

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0273659A1 (en) * 1986-12-27 1988-07-06 Takeda Chemical Industries, Ltd. Azaspiro compounds, their production and use
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
BE1007765A5 (fr) 1994-06-27 1995-10-17 Blagden Ind Plc Fut metallique a ouverture totale.
WO1999032489A1 (en) * 1997-12-23 1999-07-01 Alcon Laboratories, Inc. Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions
WO2004005293A2 (en) 2002-07-05 2004-01-15 Targacept, Inc. N-aryl diazaspiracyclic compounds and methods of preparation and use thereof
WO2005023809A1 (en) * 2003-09-10 2005-03-17 Virochem Pharma Inc. Spiro compounds and methods for the modulation of chemokine receptor activity
US8257680B1 (en) 2004-02-24 2012-09-04 The General Hospital Corporation Catalytic radiofluorination
US9017724B2 (en) 2004-02-24 2015-04-28 The General Hospital Corporation Catalytic radiofluorination
JO2676B1 (en) 2004-04-06 2012-06-17 جانسين فارماسوتيكا ان. في Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines
ES2350647T3 (es) 2005-03-08 2011-01-25 Janssen Pharmaceutica Nv Derivados de diaza-espiro-[4.4]-nonano como antagonistas de neuroquininas (nk1).
CN104974024B (zh) 2008-03-21 2017-11-14 综合医院公司 检测和治疗阿尔茨海默病和相关疾病的化合物和组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB936477A (en) * 1959-03-25 1963-09-11 Sandoz Ltd Improvements in or relating to substituted succinimides
DE1211646B (de) * 1959-03-25 1966-03-03 Sandoz Ag Verfahren zur Herstellung von Spirosuccinimiden und deren Salzen
US3198800A (en) * 1964-05-07 1965-08-03 Sandoz Ltd 2, 8-(para-f-4-oxo-butyl)-diazaspiro[4, 5]-decane-1, 3-diones
BE897058A (fr) * 1982-06-25 1983-12-16 Sandoz Sa Utilisation d'un derive du spiro-succinimide dans le traitement de la demence du type alzheimer

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172526A1 (de) * 1984-08-24 1986-02-26 Troponwerke GmbH & Co. KG Neue Benzodiazepine, Verfahren zu ihrer Herstellung sowie ihre Verwendung
US4647560A (en) * 1984-08-24 1987-03-03 Troponwerke Gmbh & Co. Kg New benzodiazepines and their use
US5780632A (en) * 1990-06-07 1998-07-14 Sumitomo Pharmaceuticals Company, Limited Imide derivatives and their production and use
EP0464846A1 (en) * 1990-07-06 1992-01-08 Sumitomo Pharmaceuticals Company, Limited Imide derivatives, and their production and use
US5532372A (en) * 1990-07-06 1996-07-02 Sumitomo Pharmaceuticals Company, Ltd. Imide derivatives, and their production and use

Also Published As

Publication number Publication date
PT78787B (en) 1986-06-05
FR2549061A1 (fr) 1985-01-18
SE8403376L (sv) 1984-12-28
HUT36793A (en) 1985-10-28
ES533735A0 (es) 1985-10-16
SE8403376D0 (sv) 1984-06-25
WO1985000171A1 (en) 1985-01-17
FI842547A0 (fi) 1984-06-25
DK310184D0 (da) 1984-06-25
FI842547A (fi) 1984-12-28
AU2983384A (en) 1985-01-03
GB2142332A (en) 1985-01-16
IT1199148B (it) 1988-12-30
NL8401907A (nl) 1985-01-16
GB8416172D0 (en) 1984-08-01
IT8448458A0 (it) 1984-06-26
ES8601202A1 (es) 1985-10-16
GR82274B (nl) 1984-12-13
IL72218A0 (en) 1984-10-31
PT78787A (en) 1984-07-01
DK310184A (da) 1984-12-28
LU85434A1 (fr) 1985-03-26

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee