DE3342736A1 - Hybridoma-antikoerper - Google Patents

Hybridoma-antikoerper

Info

Publication number
DE3342736A1
DE3342736A1 DE19833342736 DE3342736A DE3342736A1 DE 3342736 A1 DE3342736 A1 DE 3342736A1 DE 19833342736 DE19833342736 DE 19833342736 DE 3342736 A DE3342736 A DE 3342736A DE 3342736 A1 DE3342736 A1 DE 3342736A1
Authority
DE
Germany
Prior art keywords
amylase
monoclonal antibody
saliva
detection
pancreatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19833342736
Other languages
German (de)
English (en)
Inventor
Winfried Dr. phil. 8121 Pähl Albert
Willie Dr.med. Helsingborg Gerhardt
Christa Dr.rer.nat. 8132 Tutzing Hübner-Parajsz
Herbert Dr. Med. Jungfer
Helmut Dr.rer.nat. 8132 Tutzing Lenz
Kurt Walter Dr.rer.nat. 8035 Gauting Naujoks
August Wilhelm Dr.Rer.Nat. 8120 Weilheim Wahlefeld
Karl Dr.Rer.Nat. 8120 Weilheim Wulff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6215298&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3342736(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE19833342736 priority Critical patent/DE3342736A1/de
Priority to ES537835A priority patent/ES537835A0/es
Priority to YU196984A priority patent/YU45971B/sh
Priority to CA000468445A priority patent/CA1313150C/en
Priority to DD84269782A priority patent/DD233142A5/de
Priority to CS848967A priority patent/CS256383B2/cs
Priority to JP59246409A priority patent/JPS60155134A/ja
Priority to DK555584A priority patent/DK162727C/da
Priority to DE8484114172T priority patent/DE3478821D1/de
Priority to EP84114172A priority patent/EP0150309B1/de
Priority to AT84114172T priority patent/ATE44320T1/de
Priority to ZA849140A priority patent/ZA849140B/xx
Priority to FI844608A priority patent/FI83669C/fi
Priority to AU35874/84A priority patent/AU550266B2/en
Publication of DE3342736A1 publication Critical patent/DE3342736A1/de
Priority to US07/326,885 priority patent/US4939082A/en
Priority to DK257690A priority patent/DK257690A/da
Priority to JP3136054A priority patent/JPH05232117A/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/40—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving amylase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/828—Protein A
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cephalosporin Compounds (AREA)
DE19833342736 1983-11-25 1983-11-25 Hybridoma-antikoerper Ceased DE3342736A1 (de)

Priority Applications (17)

Application Number Priority Date Filing Date Title
DE19833342736 DE3342736A1 (de) 1983-11-25 1983-11-25 Hybridoma-antikoerper
ES537835A ES537835A0 (es) 1983-11-25 1984-11-21 Procedimiento para la determinacion especifica de a-amilasa de pancreas existente junto a a-amilasa de saliva
YU196984A YU45971B (sh) 1983-11-25 1984-11-22 Postopek za specifično določitev pankreas-alfa-amilaze poleg alfa-amilaze sline
CA000468445A CA1313150C (en) 1983-11-25 1984-11-22 Process and reagent for the specific determination of pancreas –-amylase
DD84269782A DD233142A5 (de) 1983-11-25 1984-11-22 Hybridoma-antikoerper
CS848967A CS256383B2 (en) 1983-11-25 1984-11-22 Reagent for specific determination of pancreas alpha-amylase
JP59246409A JPS60155134A (ja) 1983-11-25 1984-11-22 体液中のだ液α―アミラーゼの存在下にすいぞうα―アミラーゼを特異的に測定するための試薬
DK555584A DK162727C (da) 1983-11-25 1984-11-22 Monoklonalt antistof overfor spyt-alfa-amylase og fremgangsmaade til fremstilling deraf samt dets anvendelse til specifik bestemmelse af pankreas-alfa-amylase ved siden af spyt-alfa-amylase og reagens til brug ved anvendelsen
FI844608A FI83669C (fi) 1983-11-25 1984-11-23 Foerfarande foer specifik bestaemning av pankreas -amylas.
DE8484114172T DE3478821D1 (en) 1983-11-25 1984-11-23 Hybridoma antibody
EP84114172A EP0150309B1 (de) 1983-11-25 1984-11-23 Hybridoma-Antikörper
AT84114172T ATE44320T1 (de) 1983-11-25 1984-11-23 Hybridoma-antikoerper.
ZA849140A ZA849140B (en) 1983-11-25 1984-11-23 Hybridoma antibodies
AU35874/84A AU550266B2 (en) 1983-11-25 1984-11-26 Hybridoma antibodies
US07/326,885 US4939082A (en) 1983-11-25 1989-03-21 Process and monoclonal antibody for the specific determination of pancreas alpha-amylase in the presence of saliva alpha-amylase
DK257690A DK257690A (da) 1983-11-25 1990-10-25 Monoklonalt antistof overfor spyt-alfa-amylase og fremgangsmaade til fremstilling deraf
JP3136054A JPH05232117A (ja) 1983-11-25 1991-06-07 体液中のだ液α−アミラーゼの存在下にすいぞうα−アミラーゼを特異的に測定する方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833342736 DE3342736A1 (de) 1983-11-25 1983-11-25 Hybridoma-antikoerper

Publications (1)

Publication Number Publication Date
DE3342736A1 true DE3342736A1 (de) 1985-06-05

Family

ID=6215298

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19833342736 Ceased DE3342736A1 (de) 1983-11-25 1983-11-25 Hybridoma-antikoerper
DE8484114172T Expired DE3478821D1 (en) 1983-11-25 1984-11-23 Hybridoma antibody

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8484114172T Expired DE3478821D1 (en) 1983-11-25 1984-11-23 Hybridoma antibody

Country Status (14)

Country Link
US (1) US4939082A (OSRAM)
EP (1) EP0150309B1 (OSRAM)
JP (2) JPS60155134A (OSRAM)
AT (1) ATE44320T1 (OSRAM)
AU (1) AU550266B2 (OSRAM)
CA (1) CA1313150C (OSRAM)
CS (1) CS256383B2 (OSRAM)
DD (1) DD233142A5 (OSRAM)
DE (2) DE3342736A1 (OSRAM)
DK (2) DK162727C (OSRAM)
ES (1) ES537835A0 (OSRAM)
FI (1) FI83669C (OSRAM)
YU (1) YU45971B (OSRAM)
ZA (1) ZA849140B (OSRAM)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3500526A1 (de) * 1985-01-09 1986-07-10 Boehringer Mannheim Gmbh, 6800 Mannheim Spezifisch hemmender s-amylase-mak
EP0194600A3 (de) * 1985-03-08 1988-03-16 Roche Diagnostics GmbH Hemmung humaner Speichel- und Pankreasamylase durch monoklonale Antikörper
US4757001A (en) * 1984-02-16 1988-07-12 Fujirebio Kabushiki Kaisha Method of measuring biological ligand by utilizing amylase
DE3903114A1 (de) * 1989-02-02 1990-08-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung eines enzyms aus einem isoenzymgemisch sowie hierfuer geeigneter testtraeger und dessen verwendung
US5573918A (en) * 1985-07-19 1996-11-12 Boehringer Mannheim Gmbh Process and reagent for specific determination of pancreatic alpha amylase

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987000526A1 (en) * 1985-07-26 1987-01-29 The University Of Virginia Alumni Patents Foundati Immunochemical assays for human amylase isoenzymes and related monoclonal antibodies, hybridoma cell lines and production thereof
DE3929355A1 (de) * 1989-09-04 1991-03-07 Boehringer Mannheim Gmbh Verfahren zur spezifischen bestimmung von pankreas-(alpha)-amylase
JPH085919B2 (ja) * 1989-11-10 1996-01-24 日本商事株式会社 唾液―α―アミラーゼ活性阻害モノクローナル抗体およびそれを用いる膵臓―α―アミラーゼの分別定量法
GB9024970D0 (en) * 1990-11-16 1991-01-02 Genzyme Uk Ltd Assay
KR20030079382A (ko) * 2002-04-04 2003-10-10 최태부 소화 효소-지방산 복합체를 항원으로하여 생산된 항체 및이의 이용

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0093436A2 (de) * 1982-05-04 1983-11-09 Roche Diagnostics GmbH Verfahren zur Herstellung permanenter tierischer und humaner Zellinien und deren Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2258822A1 (de) * 1972-12-01 1974-06-06 Merck Patent Gmbh Verfahren und mittel zur analyse von isoenzymmustern
JPS58183098A (ja) * 1982-04-20 1983-10-26 Wako Pure Chem Ind Ltd アイソザイム分別定量法
US4474892A (en) * 1983-02-16 1984-10-02 Board Of Trustees Of The Leland Stanford Junior University Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same
DE3508384A1 (de) * 1985-03-08 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Hemmung humaner speichel- und pankreasamylase durch monoklonale antikoerper

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0093436A2 (de) * 1982-05-04 1983-11-09 Roche Diagnostics GmbH Verfahren zur Herstellung permanenter tierischer und humaner Zellinien und deren Verwendung

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Laboratoriumsblätter 32, S. 117-128, 1982 *
Nature, Vol. 256, S. 495-497, 1975 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757001A (en) * 1984-02-16 1988-07-12 Fujirebio Kabushiki Kaisha Method of measuring biological ligand by utilizing amylase
DE3500526A1 (de) * 1985-01-09 1986-07-10 Boehringer Mannheim Gmbh, 6800 Mannheim Spezifisch hemmender s-amylase-mak
EP0194600A3 (de) * 1985-03-08 1988-03-16 Roche Diagnostics GmbH Hemmung humaner Speichel- und Pankreasamylase durch monoklonale Antikörper
US5573918A (en) * 1985-07-19 1996-11-12 Boehringer Mannheim Gmbh Process and reagent for specific determination of pancreatic alpha amylase
DE3903114A1 (de) * 1989-02-02 1990-08-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung eines enzyms aus einem isoenzymgemisch sowie hierfuer geeigneter testtraeger und dessen verwendung

Also Published As

Publication number Publication date
ATE44320T1 (de) 1989-07-15
CS896784A2 (en) 1987-08-13
EP0150309A2 (de) 1985-08-07
ES8507568A1 (es) 1985-09-16
JPS60155134A (ja) 1985-08-15
DK555584A (da) 1985-05-26
DK162727C (da) 1992-05-11
ZA849140B (en) 1985-07-31
DE3478821D1 (en) 1989-08-03
AU3587484A (en) 1985-05-30
CA1313150C (en) 1993-01-26
AU550266B2 (en) 1986-03-13
JPH0436343B2 (OSRAM) 1992-06-15
JPH05232117A (ja) 1993-09-07
EP0150309A3 (en) 1985-08-21
DK555584D0 (da) 1984-11-22
DK257690D0 (da) 1990-10-25
US4939082A (en) 1990-07-03
FI844608L (fi) 1985-05-26
FI83669C (fi) 1991-08-12
EP0150309B1 (de) 1989-06-28
FI83669B (fi) 1991-04-30
YU45971B (sh) 1992-12-21
DK162727B (da) 1991-12-02
DD233142A5 (de) 1986-02-19
ES537835A0 (es) 1985-09-16
YU196984A (en) 1989-12-31
FI844608A0 (fi) 1984-11-23
CS256383B2 (en) 1988-04-15
DK257690A (da) 1990-10-25

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection