DE3327642A1 - Verfahren zur bestimmung eines partners einer immunreaktion sowie reagens zur durchfuehrung dieses verfahrens - Google Patents

Verfahren zur bestimmung eines partners einer immunreaktion sowie reagens zur durchfuehrung dieses verfahrens

Info

Publication number
DE3327642A1
DE3327642A1 DE19833327642 DE3327642A DE3327642A1 DE 3327642 A1 DE3327642 A1 DE 3327642A1 DE 19833327642 DE19833327642 DE 19833327642 DE 3327642 A DE3327642 A DE 3327642A DE 3327642 A1 DE3327642 A1 DE 3327642A1
Authority
DE
Germany
Prior art keywords
detergent
adsorbed
acceptor
partner
serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19833327642
Other languages
German (de)
English (en)
Inventor
Manfred Dr.rer.nat. 8134 Pöcking-Possenhofen Baier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE19833327642 priority Critical patent/DE3327642A1/de
Priority to US06/631,816 priority patent/US4639425A/en
Priority to AT84108708T priority patent/ATE47231T1/de
Priority to DE8484108708T priority patent/DE3480120D1/de
Priority to EP84108708A priority patent/EP0133272B1/de
Priority to JP59157743A priority patent/JPS6053846A/ja
Publication of DE3327642A1 publication Critical patent/DE3327642A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/826—Additives, e.g. buffers, diluents, preservatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE19833327642 1983-07-30 1983-07-30 Verfahren zur bestimmung eines partners einer immunreaktion sowie reagens zur durchfuehrung dieses verfahrens Withdrawn DE3327642A1 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE19833327642 DE3327642A1 (de) 1983-07-30 1983-07-30 Verfahren zur bestimmung eines partners einer immunreaktion sowie reagens zur durchfuehrung dieses verfahrens
US06/631,816 US4639425A (en) 1983-07-30 1984-07-17 Heterogeneous immunoassay and reagent therefore
AT84108708T ATE47231T1 (de) 1983-07-30 1984-07-24 Verfahren zur bestimmung eines partners einer immunreaktion sowie reagens zur durchfuehrung dieses verfahrens.
DE8484108708T DE3480120D1 (en) 1983-07-30 1984-07-24 Method for the determination of a partner of an immunological reaction and reagents for performing the method
EP84108708A EP0133272B1 (de) 1983-07-30 1984-07-24 Verfahren zur Bestimmung eines Partners einer Immunreaktion sowie Reagens zur Durchführung dieses Verfahrens
JP59157743A JPS6053846A (ja) 1983-07-30 1984-07-30 免疫反応の成分を測定する方法及び試薬

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833327642 DE3327642A1 (de) 1983-07-30 1983-07-30 Verfahren zur bestimmung eines partners einer immunreaktion sowie reagens zur durchfuehrung dieses verfahrens

Publications (1)

Publication Number Publication Date
DE3327642A1 true DE3327642A1 (de) 1985-02-14

Family

ID=6205408

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19833327642 Withdrawn DE3327642A1 (de) 1983-07-30 1983-07-30 Verfahren zur bestimmung eines partners einer immunreaktion sowie reagens zur durchfuehrung dieses verfahrens
DE8484108708T Expired DE3480120D1 (en) 1983-07-30 1984-07-24 Method for the determination of a partner of an immunological reaction and reagents for performing the method

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8484108708T Expired DE3480120D1 (en) 1983-07-30 1984-07-24 Method for the determination of a partner of an immunological reaction and reagents for performing the method

Country Status (5)

Country Link
US (1) US4639425A (OSRAM)
EP (1) EP0133272B1 (OSRAM)
JP (1) JPS6053846A (OSRAM)
AT (1) ATE47231T1 (OSRAM)
DE (2) DE3327642A1 (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3725504A1 (de) * 1987-07-31 1989-02-09 Thraenhart Olaf Priv Doz Dr Verfahren und vorrichtung zum nachweis von antikoerpern und antigenen
US5374530A (en) * 1988-08-05 1994-12-20 Eniricerche S.P.A. Immunoenzymatic single-plate ELISA method with competitive inhibition for detecting antisporozoite antibodies of plasmodium falciparum

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5151266A (en) * 1985-08-20 1992-09-29 Neorx Corporation Use of anionic detergents with conjugates of monoclonal or polyclonal antibodies
DE3530942A1 (de) * 1985-08-29 1987-03-12 Boehringer Mannheim Gmbh Verfahren und reagenz zur beseitigung der stoerung der analyt-wiederfindung in plasmaproben
DE3532626A1 (de) * 1985-09-12 1987-03-19 Boehringer Mannheim Gmbh Verfahren zur bestimmung eines partners einer immunreaktion
NL8600056A (nl) * 1986-01-13 1987-08-03 Nederlanden Staat Werkwijze voor het aantonen van een lid van een immunologisch paar, werkwijze voor het bereiden van een drager waaraan een lid van een immunologisch paar is gebonden alsmede analyse-inrichting geschikt voor het uitvoeren van dergelijke werkwijzen.
DE3717402A1 (de) * 1987-05-23 1988-12-08 Behringwerke Ag Verfahren zur bestimmung von proteinen und mittel dazu
US5017474A (en) * 1988-02-12 1991-05-21 Eastman Kodak Company Wash solution, test kit and method for the determination of an immunological ligand
DE3807478A1 (de) * 1988-03-08 1989-09-21 Behringwerke Ag Mittel fuer immunchemische tests enthaltend aminoxide
US5268299A (en) * 1988-04-14 1993-12-07 Eastman Kodak Company Diluent composition useful in the detection of antibodies in assays
US5077198A (en) * 1988-04-14 1991-12-31 Eastman Kodak Company Diagnostic kit and method for rapid detection of antibodies
JP2684069B2 (ja) * 1988-10-13 1997-12-03 昇一 首藤 免疫学的活性物質の測定方法及びそのための試薬
CA2044629A1 (en) * 1989-11-02 1991-05-03 Kimihiko Matsuzawa Method for the immunological assay of human thrombomodulin, reagent therefor and kit therefor
DE4035174A1 (de) * 1990-11-06 1992-05-07 Biotest Ag Verfahren zur bestimmung von proteinen in koerperfluessigkeiten und mittel zur durchfuehrung des verfahrens
US5424219A (en) * 1991-10-25 1995-06-13 Cytech Biomedical, Inc. Method of performing assays for biomolecules and solid supports for use in such methods
US5322391A (en) * 1992-09-01 1994-06-21 Foster-Miller, Inc. Guided mole
US5627080A (en) * 1994-07-29 1997-05-06 Beckman Instruments, Inc. Detergent-facilitated immunoassay for the rapid and quantitative assay of pharmacological agents
US5639626A (en) * 1994-11-15 1997-06-17 Chiron Diagnostics Corporation Reagents for specific binding assays
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
DE69939811D1 (de) * 1998-07-30 2008-12-11 Advanced Life Science Inst Inc Verfahren zur bestimmung von hepatitis c viren
EP1308730B1 (en) * 2000-08-11 2011-12-28 Advanced Life Science Institute, Inc. Method of detecting or assaying hbv
CA2439404A1 (en) * 2001-03-07 2002-09-12 Bio-Rad Laboratories Inc. Assay system for simultaneous detection and measurement of multiple modified cellular proteins
US6984497B2 (en) * 2002-04-05 2006-01-10 Bio-Rad Laboratories, Inc. Reducing non-specific binding in immunoassays performed on polymeric solid phases
JP2009085703A (ja) * 2007-09-28 2009-04-23 Fujifilm Corp 高感度免疫測定方法
EP2042870A1 (en) 2007-09-28 2009-04-01 Fujifilm Corporation Method of high sensitive immunoassay
US9651549B2 (en) * 2012-07-13 2017-05-16 Genisphere, Llc Lateral flow assays using DNA dendrimers
US20160051693A1 (en) 2013-03-21 2016-02-25 Genisphere, Llc Cellular Delivery of DNA Intercalating Agents
JP7366541B2 (ja) 2016-02-19 2023-10-23 コード バイオセラピューティクス インコーポレイテッド 核酸キャリア及び治療上の使用方法
JPWO2021182558A1 (OSRAM) * 2020-03-12 2021-09-16

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273756A (en) * 1978-07-28 1981-06-16 Abbott Laboratories Immunoassay for class specific antibodies
US4313927A (en) * 1979-10-19 1982-02-02 Ames-Yissum Ltd. Immunoassay method for detecting viral antibodies in whole blood samples
US4357310A (en) * 1980-08-08 1982-11-02 Baxter Travenol Laboratories, Inc. Method and composition for reducing the nonspecific binding of radioiodinated protein hormones

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5443572B2 (OSRAM) * 1974-07-08 1979-12-20
IL48804A (en) * 1975-01-29 1979-05-31 Baxter Travenol Lab Imminological reagent comprising a mixture of polyethyleneglycol and a nonionic surfactant
JPS5344622A (en) * 1976-09-30 1978-04-21 Mochida Pharm Co Ltd Immunologically measuring method
DE2829531A1 (de) * 1978-07-05 1980-01-24 Heuck Claus Christian Dr Rer N Verfahren zur quantitativen bestimmung eines serumproteins in getruebten serum- und plasma-proben
US4241175A (en) * 1978-12-18 1980-12-23 Merck & Co., Inc. Assay for hepatitis B core antibody
US4273867A (en) * 1979-04-05 1981-06-16 Mallinckrodt, Inc. Method and reagent for counteracting lipemic interference
US4267270A (en) * 1979-05-21 1981-05-12 Enzyme Technology, Inc. Method for the determination of antigens and antibodies using site-deactivating media
US4492762A (en) * 1981-12-11 1985-01-08 Abbott Laboratories Fluorescent polarization immunoassays
JPS58187862A (ja) * 1982-04-27 1983-11-02 Sanyo Chem Ind Ltd 免疫測定改良剤および改良方法
US4454232A (en) * 1982-06-07 1984-06-12 Bio-Rad Laboratories, Inc. Estriol assay
JPS5997057A (ja) * 1982-11-26 1984-06-04 Kainosu:Kk 抗血清試薬
GB8317855D0 (en) * 1983-06-30 1983-08-03 Iq Bio Ltd Biochemical detection method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273756A (en) * 1978-07-28 1981-06-16 Abbott Laboratories Immunoassay for class specific antibodies
US4313927A (en) * 1979-10-19 1982-02-02 Ames-Yissum Ltd. Immunoassay method for detecting viral antibodies in whole blood samples
US4357310A (en) * 1980-08-08 1982-11-02 Baxter Travenol Laboratories, Inc. Method and composition for reducing the nonspecific binding of radioiodinated protein hormones

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3725504A1 (de) * 1987-07-31 1989-02-09 Thraenhart Olaf Priv Doz Dr Verfahren und vorrichtung zum nachweis von antikoerpern und antigenen
US5374530A (en) * 1988-08-05 1994-12-20 Eniricerche S.P.A. Immunoenzymatic single-plate ELISA method with competitive inhibition for detecting antisporozoite antibodies of plasmodium falciparum

Also Published As

Publication number Publication date
EP0133272B1 (de) 1989-10-11
EP0133272A3 (en) 1987-12-02
EP0133272A2 (de) 1985-02-20
JPH0465344B2 (OSRAM) 1992-10-19
US4639425A (en) 1987-01-27
JPS6053846A (ja) 1985-03-27
DE3480120D1 (en) 1989-11-16
ATE47231T1 (de) 1989-10-15

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8139 Disposal/non-payment of the annual fee