DE3322459A1 - Verfahren zur herstellung von arylalkanoatestern und arylalkancarbonsaeuren (ausdiesen) - Google Patents

Verfahren zur herstellung von arylalkanoatestern und arylalkancarbonsaeuren (ausdiesen)

Info

Publication number
DE3322459A1
DE3322459A1 DE19833322459 DE3322459A DE3322459A1 DE 3322459 A1 DE3322459 A1 DE 3322459A1 DE 19833322459 DE19833322459 DE 19833322459 DE 3322459 A DE3322459 A DE 3322459A DE 3322459 A1 DE3322459 A1 DE 3322459A1
Authority
DE
Germany
Prior art keywords
salt
alkali metal
ketal
heptane
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19833322459
Other languages
German (de)
English (en)
Other versions
DE3322459C2 (enExample
Inventor
Sanjay Indubhai Kalamazoo Mich. Amin
Jerry Arnold Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Manufacturing Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Manufacturing Co filed Critical Upjohn Manufacturing Co
Publication of DE3322459A1 publication Critical patent/DE3322459A1/de
Application granted granted Critical
Publication of DE3322459C2 publication Critical patent/DE3322459C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE19833322459 1982-07-09 1983-06-22 Verfahren zur herstellung von arylalkanoatestern und arylalkancarbonsaeuren (ausdiesen) Granted DE3322459A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/396,967 US4623736A (en) 1982-07-09 1982-07-09 Arylalkanoic acid process improvement

Publications (2)

Publication Number Publication Date
DE3322459A1 true DE3322459A1 (de) 1984-01-12
DE3322459C2 DE3322459C2 (enExample) 1993-03-18

Family

ID=23569336

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19833322459 Granted DE3322459A1 (de) 1982-07-09 1983-06-22 Verfahren zur herstellung von arylalkanoatestern und arylalkancarbonsaeuren (ausdiesen)

Country Status (8)

Country Link
US (1) US4623736A (enExample)
JP (1) JPS5921647A (enExample)
CH (1) CH661268A5 (enExample)
DE (1) DE3322459A1 (enExample)
FR (1) FR2529886B1 (enExample)
GB (1) GB2123416B (enExample)
IT (1) IT1165459B (enExample)
NL (1) NL192108C (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005075401A1 (de) * 2004-02-04 2005-08-18 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von 2,5-dimethylphenylessigsäure

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE35810T1 (de) * 1984-04-06 1988-08-15 Zambon Spa Verfahren zur herstellung von optisch aktiven alpha-arylalkansaeuren und ihre zwischenprodukte.
DE3584754D1 (de) * 1984-09-24 1992-01-09 Nobel Chemicals Ab Verfahren zur herstellung von arylalkylketonen.
US5792886A (en) * 1997-01-08 1998-08-11 Albemarle Corporation Production of racemic 2-(6-methoxy-2-naphthyl) propionic acid of precursors thereof
US6096920A (en) * 1997-01-08 2000-08-01 Albemarle Corporation Preparation of carboxylic compounds and their derivatives
US6080888A (en) * 1997-01-08 2000-06-27 Albemarle Corporation Preparation of olefinic compounds and carboxylic derivatives thereof
US5859292A (en) * 1997-12-11 1999-01-12 Albemarle Corporation Preparation of high purity sodium (S)-2(6-methoxy-2-naphthyl)propionate
US5874614A (en) * 1997-12-11 1999-02-23 Albemarle Corporation Sodium (S)-2-(6-methoxy-2-naphthyl)propionate monohydrate
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
CL2007002425A1 (es) * 2006-08-22 2008-06-27 Albermarle Corp Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica.
CN103183604B (zh) * 2011-12-28 2015-07-29 药源药物化学（上海）有限公司 维达洛芬的制备方法
CN105439849A (zh) * 2014-09-02 2016-03-30 襄阳新叶生物科技有限公司 采用固体催化剂的布洛芬制备方法
CN109761803A (zh) * 2019-01-29 2019-05-17 湖南九典制药股份有限公司 一种萘普生关键中间体的合成方法
CN113045534A (zh) * 2021-03-23 2021-06-29 山东新华制药股份有限公司 一种布洛芬缩酮化工艺
CN117342938A (zh) * 2023-10-08 2024-01-05 常州大学 一种布洛芬的制备方法
CN118543369A (zh) * 2024-05-28 2024-08-27 大连理工大学 一类羧酸锌催化剂、制备方法及其在聚对苯二甲酸乙二酯醇解中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034871B1 (en) * 1980-02-26 1985-07-31 BLASCHIM S.p.A. Process for preparing esters of alkanoic acids via rearrangement of alpha-haloketals

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034871B1 (en) * 1980-02-26 1985-07-31 BLASCHIM S.p.A. Process for preparing esters of alkanoic acids via rearrangement of alpha-haloketals

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J. Amer. Chem. Soc. 73(1951), S. 4702 *
J. Amer. Chem. Soc. 93(1970), S. 711 *
Tetrahedron Settess, (1982), S. 1385 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005075401A1 (de) * 2004-02-04 2005-08-18 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von 2,5-dimethylphenylessigsäure
US7579500B2 (en) 2004-02-04 2009-08-25 Archer-Daniels-Midland Company Method for producing 2,5-dimethylphenyl acetic acid
US7629476B2 (en) 2004-02-04 2009-12-08 Bayer Cropscience Ag Method for producing 2,5-dimethylphenyl acetic acid

Also Published As

Publication number Publication date
JPS5921647A (ja) 1984-02-03
JPH0446257B2 (enExample) 1992-07-29
NL192108B (nl) 1996-10-01
NL8302327A (nl) 1984-02-01
GB8317894D0 (en) 1983-08-03
IT1165459B (it) 1987-04-22
GB2123416A (en) 1984-02-01
NL192108C (nl) 1997-02-04
CH661268A5 (de) 1987-07-15
DE3322459C2 (enExample) 1993-03-18
GB2123416B (en) 1985-11-27
FR2529886B1 (fr) 1987-10-30
IT8321973A0 (it) 1983-07-07
FR2529886A1 (fr) 1984-01-13
US4623736A (en) 1986-11-18

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: THE UPJOHN CO., KALAMAZOO, MICH., US

8128 New person/name/address of the agent

Representative=s name: HENKEL, G., DR.PHIL. FEILER, L., DR.RER.NAT. HAENZ

8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PHARMACIA & UPJOHN CO., KALAMAZOO, MICH., US