DE3320495A1 - Mikrobiologisch hergestellte d-2-hydroxy-4-methylpentansaeure-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung - Google Patents

Mikrobiologisch hergestellte d-2-hydroxy-4-methylpentansaeure-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung

Info

Publication number
DE3320495A1
DE3320495A1 DE19833320495 DE3320495A DE3320495A1 DE 3320495 A1 DE3320495 A1 DE 3320495A1 DE 19833320495 DE19833320495 DE 19833320495 DE 3320495 A DE3320495 A DE 3320495A DE 3320495 A1 DE3320495 A1 DE 3320495A1
Authority
DE
Germany
Prior art keywords
acid
hydroxy
keto
methylpentanoic
methylpentanoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19833320495
Other languages
German (de)
English (en)
Inventor
Werner Dr. 3300 Braunschweig Hummel
Maria-Regina Dr. 3340 Wolfenbüttel Kula
Wolfgang Dipl.-Chem. Dr. 6454 Bruchköbel Leuchtenberger
Horst 3332 Salzgitter Schütte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH filed Critical Degussa GmbH
Priority to DE19833320495 priority Critical patent/DE3320495A1/de
Priority to DE8484103776T priority patent/DE3469565D1/de
Priority to EP84103776A priority patent/EP0130288B1/de
Priority to DK262784A priority patent/DK262784A/da
Priority to CA000456000A priority patent/CA1210348A/en
Priority to US06/617,738 priority patent/US4609623A/en
Priority to JP59115650A priority patent/JPS6012975A/ja
Publication of DE3320495A1 publication Critical patent/DE3320495A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus
    • Y10S435/856—Lactobacillus casei

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE19833320495 1983-06-07 1983-06-07 Mikrobiologisch hergestellte d-2-hydroxy-4-methylpentansaeure-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung Withdrawn DE3320495A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE19833320495 DE3320495A1 (de) 1983-06-07 1983-06-07 Mikrobiologisch hergestellte d-2-hydroxy-4-methylpentansaeure-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung
DE8484103776T DE3469565D1 (en) 1983-06-07 1984-04-05 Microbiologically prepared d-2-hydroxy-4-methylpentanoic-acid dehydrogenase, process for its production and its use
EP84103776A EP0130288B1 (de) 1983-06-07 1984-04-05 Mikrobiologisch hergestellte D-2-Hydroxy-4-methylpentansäure-Dehydrogenase, Verfahren zu ihrer Gewinnung und ihre Verwendung
DK262784A DK262784A (da) 1983-06-07 1984-05-28 Mikrobiologisk fremstillet d-2-hydroxy-4-methylpentansyredehydrogenase, fremgangsmaade til dets udvinding og dets anvendelse
CA000456000A CA1210348A (en) 1983-06-07 1984-06-06 Microbiologically produced d-2-hydroxy-4-methyl- pentanoic acid dehydrogenase, process for producing same, and its use
US06/617,738 US4609623A (en) 1983-06-07 1984-06-06 Microbiologically produced D-2-hydroxy-4-methylpentanoic acid dehydrogenase, process for its production and its use
JP59115650A JPS6012975A (ja) 1983-06-07 1984-06-07 微生物学的に得られるｄ−２−ヒドロキシ−４−メチルペンタン酸−デヒドロゲナ−ゼ及びそれを取得する方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833320495 DE3320495A1 (de) 1983-06-07 1983-06-07 Mikrobiologisch hergestellte d-2-hydroxy-4-methylpentansaeure-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung

Publications (1)

Publication Number Publication Date
DE3320495A1 true DE3320495A1 (de) 1984-12-13

Family

ID=6200840

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19833320495 Withdrawn DE3320495A1 (de) 1983-06-07 1983-06-07 Mikrobiologisch hergestellte d-2-hydroxy-4-methylpentansaeure-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung
DE8484103776T Expired DE3469565D1 (en) 1983-06-07 1984-04-05 Microbiologically prepared d-2-hydroxy-4-methylpentanoic-acid dehydrogenase, process for its production and its use

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8484103776T Expired DE3469565D1 (en) 1983-06-07 1984-04-05 Microbiologically prepared d-2-hydroxy-4-methylpentanoic-acid dehydrogenase, process for its production and its use

Country Status (6)

Country Link
US (1) US4609623A (https=)
EP (1) EP0130288B1 (https=)
JP (1) JPS6012975A (https=)
CA (1) CA1210348A (https=)
DE (2) DE3320495A1 (https=)
DK (1) DK262784A (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3536662A1 (de) * 1985-10-15 1987-05-27 Degussa Mikrobiologisch hergestellte d(-)-mandelat-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung
JP2752754B2 (ja) * 1988-02-08 1998-05-18 ダイセル化学工業株式会社 光学活性２―ヒドロキシ―４―フェニル酪酸の製造法
US5256552A (en) * 1988-02-08 1993-10-26 Daicel Chemical Industries, Ltd. Process for the production of optically active 2-hydroxy-4-phenylbutyric acid
WO1989007648A1 (fr) * 1988-02-12 1989-08-24 Daicel Chemical Industries, Ltd. Procede de preparation de derives de l'acide 2-hydroxy optiquement actifs
US5371014A (en) * 1988-02-12 1994-12-06 Daicel Chemical Industries, Ltd. Process for the production of optically active 2-hydroxy acid esters using microbes to reduce the 2-oxo precursor
US5264347A (en) * 1988-09-16 1993-11-23 Kernforschungsanlage Juelich Gmbh Method for the determination of α-ketoisocaproate in biological samples using D-α-hydroxyisocaproic dehydrogenase from lactobacillus casei
DE3831450A1 (de) * 1988-09-16 1990-03-22 Kernforschungsanlage Juelich Verfahren zur bestimmung von (alpha)-ketoisocaproat in biologischen proben und dafuer geeigneter analysensatz
GB9413710D0 (en) * 1994-07-07 1994-08-24 Genzyme Ltd Chiral synthesis
JP4154182B2 (ja) * 2002-07-16 2008-09-24 ダイセル化学工業株式会社 α−ケト酸還元酵素、その製造方法、およびこれを利用した光学活性α−ヒドロキシ酸の製造方法
KR101757785B1 (ko) 2016-11-15 2017-07-14 한국식품연구원 2-하이드록시아이소카프로익 에시드(2-hydroxyisocaproic acid) 생성능이 우수한 류코노스톡 락티스 WIKIM48 및 이를 포함하는 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH628009A5 (de) * 1977-07-26 1982-02-15 Hoffmann La Roche Verfahren zur herstellung von optisch aktiven alpha-hydroxycarbonsaeuren.
DE2841414C2 (de) * 1978-09-22 1980-04-03 Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf), 3300 Braunschweig Verfahren zur Herstellung von an Makromoleküle gebundenen, ein Adeninringsystem enthaltenden Koenzymen
DE2930087A1 (de) * 1979-07-25 1981-02-26 Biotechnolog Forschung Gmbh Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden alpha -hydroxycarbonsaeuren
EP0103210B1 (de) * 1982-09-14 1987-11-25 Degussa Aktiengesellschaft L-2-Hydroxy-4-methylpentansäure-Dehydrogenase, Verfahren zu ihrer Gewinnung und ihre Verwendung

Also Published As

Publication number Publication date
CA1210348A (en) 1986-08-26
DK262784D0 (da) 1984-05-28
EP0130288A3 (en) 1985-10-02
US4609623A (en) 1986-09-02
JPS6012975A (ja) 1985-01-23
EP0130288B1 (de) 1988-03-02
EP0130288A2 (de) 1985-01-09
DK262784A (da) 1984-12-08
DE3469565D1 (en) 1988-04-07
JPH0127717B2 (https=) 1989-05-30

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Legal Events

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8139 Disposal/non-payment of the annual fee