DE3174705D1 - Synthesis of tumor antigenic determinant - Google Patents
Synthesis of tumor antigenic determinantInfo
- Publication number
- DE3174705D1 DE3174705D1 DE8181303087T DE3174705T DE3174705D1 DE 3174705 D1 DE3174705 D1 DE 3174705D1 DE 8181303087 T DE8181303087 T DE 8181303087T DE 3174705 T DE3174705 T DE 3174705T DE 3174705 D1 DE3174705 D1 DE 3174705D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- synthesis
- antigenic determinant
- tumor antigenic
- artificial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 230000000890 antigenic effect Effects 0.000 title 1
- XDMCWZFLLGVIID-SXPRBRBTSA-N O-(3-O-D-galactosyl-N-acetyl-beta-D-galactosaminyl)-L-serine Chemical compound CC(=O)N[C@H]1[C@H](OC[C@H]([NH3+])C([O-])=O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 XDMCWZFLLGVIID-SXPRBRBTSA-N 0.000 abstract 1
- 206010053613 Type IV hypersensitivity reaction Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000005951 type IV hypersensitivity Effects 0.000 abstract 1
- 208000027930 type IV hypersensitivity disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57469—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving tumor associated glycolinkage, i.e. TAG
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8022656 | 1980-07-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3174705D1 true DE3174705D1 (en) | 1986-07-03 |
Family
ID=10514682
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8181303087T Expired DE3174705D1 (en) | 1980-07-10 | 1981-07-07 | Synthesis of tumor antigenic determinant |
Country Status (6)
Country | Link |
---|---|
US (1) | US4866041A (de) |
EP (1) | EP0044188B1 (de) |
JP (4) | JPS5745197A (de) |
AT (1) | ATE20070T1 (de) |
CA (1) | CA1203532A (de) |
DE (1) | DE3174705D1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4386026A (en) * | 1981-04-20 | 1983-05-31 | Merck & Co., Inc. | Cell-specific glycopeptide ligands |
AU561066B2 (en) * | 1982-03-22 | 1987-04-30 | Biocarb Ab | Antibacterial composition containing an oligosaccharide |
DE3220426A1 (de) * | 1982-05-29 | 1983-12-01 | Behringwerke Ag, 3550 Marburg | Chemische verbindung, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der malaria |
JPS58211660A (ja) * | 1982-06-03 | 1983-12-09 | Otsuka Pharmaceut Co Ltd | フコ−ス抗原を識別する抗体の製造法 |
EP0111005B1 (de) * | 1982-06-03 | 1988-04-20 | Otsuka Pharmaceutical Co., Ltd. | Fucose-Antigene, Verfahren zu ihrer Herstellung und gegen diese gerichtete Antikörper, Testeinheit, enthaltend das Fucose Antigen und ein Verfahren zur Bestimmung von tumorassoziierten Zuckerketten |
JPS58211661A (ja) * | 1982-06-03 | 1983-12-09 | Otsuka Pharmaceut Co Ltd | 癌関連糖鎖の測定法及び癌診断用試薬 |
JPS58213722A (ja) * | 1982-06-03 | 1983-12-12 | Otsuka Pharmaceut Co Ltd | フコ−ス抗原の製造法 |
US4629692A (en) * | 1982-12-06 | 1986-12-16 | Miles Laboratories, Inc. | Immunoassay for nonenzymatically glucosylated proteins and protein fragments an index of glycemia |
US4767622A (en) * | 1983-08-19 | 1988-08-30 | University Of Illinois | Method and materials for development of immunological responses protective against malarial infection |
JPS63264493A (ja) * | 1986-12-29 | 1988-11-01 | Mect Corp | 活性カルボニル基を持つシアル酸誘導体 |
US5034516A (en) * | 1987-08-04 | 1991-07-23 | University Of Ottawa | Synthetic antigens of sialic acid and derivatives thereof |
US5192661A (en) * | 1987-08-04 | 1993-03-09 | University Of Ottawa | Multicomponent kit containing an antibody to a synthetic antigen of sialic acid |
US5079353A (en) * | 1987-12-02 | 1992-01-07 | Chembiomed, Ltd. | Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation |
US5376531A (en) * | 1992-09-03 | 1994-12-27 | Northwestern University | Method of detecting cancer |
WO1995029927A2 (en) * | 1994-05-02 | 1995-11-09 | Biomira, Inc. | Process for preparation of glycosides of tumor-associated carbohydrate antigens |
GB2306400A (en) * | 1995-10-27 | 1997-05-07 | Hewlett Packard Co | Micro-tooth carriage drive system for inkjet printhead |
US8850964B2 (en) | 2005-10-20 | 2014-10-07 | Conagra Foods Rdm, Inc. | Cooking method and apparatus |
US8302528B2 (en) | 2005-10-20 | 2012-11-06 | Conagra Foods Rdm, Inc. | Cooking method and apparatus |
CA2527770C (en) | 2005-11-21 | 2014-07-22 | Steven M. Parsons | Food tray |
US8866056B2 (en) | 2007-03-02 | 2014-10-21 | Conagra Foods Rdm, Inc. | Multi-component packaging system and apparatus |
USD639656S1 (en) | 2010-09-08 | 2011-06-14 | Con Agra Foods RDM, Inc. | Container lid |
USD638701S1 (en) | 2010-09-08 | 2011-05-31 | Conagra Foods Rdm, Inc. | Container |
USD639186S1 (en) | 2010-09-08 | 2011-06-07 | Conagra Foods Rdm, Inc. | Container with sleeve |
USD680426S1 (en) | 2012-06-12 | 2013-04-23 | Conagra Foods Rdm, Inc. | Container |
CN111537315B (zh) * | 2020-07-13 | 2020-10-02 | 天津德祥生物技术有限公司 | 红细胞膜分离液和红细胞膜分离方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1544908A (en) * | 1975-07-08 | 1979-04-25 | Chembiomed Ltd | Artificial oligosaccharide antigenic determinants |
GB1603609A (en) * | 1977-04-14 | 1981-11-25 | Chembiomed Ltd | O-protected 2-azido-2-deoxy-glycosyl nitrates |
-
1981
- 1981-06-26 CA CA000382306A patent/CA1203532A/en not_active Expired
- 1981-07-07 AT AT81303087T patent/ATE20070T1/de not_active IP Right Cessation
- 1981-07-07 DE DE8181303087T patent/DE3174705D1/de not_active Expired
- 1981-07-07 EP EP81303087A patent/EP0044188B1/de not_active Expired
- 1981-07-10 JP JP56107178A patent/JPS5745197A/ja active Granted
-
1987
- 1987-07-10 JP JP62171357A patent/JPS6399091A/ja active Granted
-
1988
- 1988-09-01 US US07/239,228 patent/US4866041A/en not_active Expired - Fee Related
-
1989
- 1989-02-02 JP JP1022756A patent/JPH01230591A/ja active Granted
- 1989-02-02 JP JP1022757A patent/JPH01230592A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
EP0044188A3 (en) | 1982-03-10 |
JPH032873B2 (de) | 1991-01-17 |
JPS5745197A (en) | 1982-03-13 |
CA1203532A (en) | 1986-04-22 |
JPH0138798B2 (de) | 1989-08-16 |
JPH0138120B2 (de) | 1989-08-11 |
US4866041A (en) | 1989-09-12 |
JPH01230592A (ja) | 1989-09-14 |
JPS6399091A (ja) | 1988-04-30 |
JPH01230591A (ja) | 1989-09-14 |
ATE20070T1 (de) | 1986-06-15 |
EP0044188A2 (de) | 1982-01-20 |
EP0044188B1 (de) | 1986-05-28 |
JPH0343280B2 (de) | 1991-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |