DE3172138D1 - Enzyme inhibitors - Google Patents

Enzyme inhibitors

Info

Publication number
DE3172138D1
DE3172138D1 DE8181303585T DE3172138T DE3172138D1 DE 3172138 D1 DE3172138 D1 DE 3172138D1 DE 8181303585 T DE8181303585 T DE 8181303585T DE 3172138 T DE3172138 T DE 3172138T DE 3172138 D1 DE3172138 D1 DE 3172138D1
Authority
DE
Germany
Prior art keywords
enzyme inhibitors
inhibitors
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181303585T
Other languages
English (en)
Inventor
Michael Szelke
David Michael Jones
Alan Hallett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Application granted granted Critical
Publication of DE3172138D1 publication Critical patent/DE3172138D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86—Renin inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8181303585T 1980-08-06 1981-08-05 Enzyme inhibitors Expired DE3172138D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8025579 1980-08-06
GB8118194 1981-06-12

Publications (1)

Publication Number Publication Date
DE3172138D1 true DE3172138D1 (en) 1985-10-10

Family

ID=26276457

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181303585T Expired DE3172138D1 (en) 1980-08-06 1981-08-05 Enzyme inhibitors

Country Status (9)

Country Link
US (1) US4424207A (de)
EP (1) EP0045665B1 (de)
AU (1) AU549157B2 (de)
DE (1) DE3172138D1 (de)
DK (1) DK349481A (de)
ES (1) ES504575A0 (de)
FI (1) FI812427L (de)
IE (1) IE51471B1 (de)
NO (1) NO812612L (de)

Families Citing this family (186)

* Cited by examiner, † Cited by third party
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GB8305985D0 (en) * 1983-03-04 1983-04-07 Szelke M Enzyme inhibition
IT1164239B (it) * 1983-05-25 1987-04-08 Anic Spa Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica
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JPS60163899A (ja) * 1984-02-03 1985-08-26 Sankyo Co Ltd レニン阻害ペプチド類
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AU7381581A (en) 1982-02-11
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US4424207A (en) 1984-01-03
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IE51471B1 (en) 1986-12-24
EP0045665B1 (de) 1985-09-04
FI812427L (fi) 1982-02-07
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ES504575A0 (es) 1983-04-01
DK349481A (da) 1982-02-07
EP0045665A1 (de) 1982-02-10

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