DE3137125A1 - Verwendung von pyridoxin-(alpha)-ketoglutarat fuer die prophylaxe der hyperlactacidaemie - Google Patents

Verwendung von pyridoxin-(alpha)-ketoglutarat fuer die prophylaxe der hyperlactacidaemie

Info

Publication number
DE3137125A1
DE3137125A1 DE19813137125 DE3137125A DE3137125A1 DE 3137125 A1 DE3137125 A1 DE 3137125A1 DE 19813137125 DE19813137125 DE 19813137125 DE 3137125 A DE3137125 A DE 3137125A DE 3137125 A1 DE3137125 A1 DE 3137125A1
Authority
DE
Germany
Prior art keywords
ketoglutarate
pyridoxine
toxic
prophylaxis
pak
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19813137125
Other languages
German (de)
English (en)
Other versions
DE3137125C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Francesco Milano Fici
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Luso Farmaco dItalia SpA
Original Assignee
Istituto Luso Farmaco dItalia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Luso Farmaco dItalia SpA filed Critical Istituto Luso Farmaco dItalia SpA
Publication of DE3137125A1 publication Critical patent/DE3137125A1/de
Application granted granted Critical
Publication of DE3137125C2 publication Critical patent/DE3137125C2/de
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19813137125 1980-09-22 1981-09-18 Verwendung von pyridoxin-(alpha)-ketoglutarat fuer die prophylaxe der hyperlactacidaemie Granted DE3137125A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT24827/80A IT1141070B (it) 1980-09-22 1980-09-22 Impiego dell'alfa-chetoglutarato di piridossina nella profilassi della iperlattacidemia

Publications (2)

Publication Number Publication Date
DE3137125A1 true DE3137125A1 (de) 1982-04-01
DE3137125C2 DE3137125C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-04-06

Family

ID=11214855

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813137125 Granted DE3137125A1 (de) 1980-09-22 1981-09-18 Verwendung von pyridoxin-(alpha)-ketoglutarat fuer die prophylaxe der hyperlactacidaemie

Country Status (12)

Country Link
US (1) US4361570A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5782316A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE890454A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1177408A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH655009A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3137125A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2490493B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2084018A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1141070B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8104357A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE459899B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA816242B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
DK1169322T3 (da) 1999-03-08 2006-03-06 Medicure Inc Pyridoxalanaloger til behandling af lidelser foranlediget af vitamin B6-mangel
AU5840200A (en) * 1999-07-13 2001-01-30 Medicure Inc. Treatment of diabetes and related pathologies
EP1210117A2 (en) * 1999-08-24 2002-06-05 Medicure International Inc. Compositons for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds
ATE293119T1 (de) 2000-02-29 2005-04-15 Medicure Int Inc Cardioprotektive phosphonate
US7442689B2 (en) * 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
JP2003528146A (ja) 2000-03-28 2003-09-24 メディキュア インターナショナル インコーポレイテッド 脳血管疾患の治療
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
NZ523815A (en) 2000-07-07 2004-07-30 Medicure Int Inc Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
US20040121988A1 (en) * 2001-03-28 2004-06-24 Medicure International Inc. Treatment of cerebrovascular disease
US20040186077A1 (en) * 2003-03-17 2004-09-23 Medicure International Inc. Novel heteroaryl phosphonates as cardioprotective agents
US20070060549A1 (en) * 2004-08-10 2007-03-15 Friesen Albert D Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
US7459468B2 (en) 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
JP2008517956A (ja) 2004-10-28 2008-05-29 メディキュア・インターナショナル・インコーポレーテッド 二重の抗血小板性/抗凝固性ピリドキシン類似体
US20090156648A1 (en) * 2007-12-12 2009-06-18 Iovate T. & P. Inc. Preparations containing pyridoxine and alpha-hydroxyisocaproic acid (HICA)
WO2009073944A1 (en) * 2007-12-12 2009-06-18 Iovate T. & P. Inc. USE OF PYRIDOXINE α-HYDROXYISOCAPROATE TO REDUCE METABOLIC ACIDOSIS AND AMMONIA ACCUMULATION
US10278327B2 (en) 2014-05-09 2019-05-07 Shakespeare Company, Llc Trimmer head for use with line and blades
WO2020086733A1 (en) * 2018-10-24 2020-04-30 Ponce De Leon Health Designated Activity Company Nicotinamide riboside compositions for healthspan extension

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1958226A1 (de) * 1968-11-22 1970-05-27 Made Labor Sa Pyridoxin-alpha-ketoglutarat

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6453M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1967-06-13 1968-11-12
US3784553A (en) * 1972-01-17 1974-01-08 Made Labor Sa Pyridoxine alpha-ketoglutarate and its derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1958226A1 (de) * 1968-11-22 1970-05-27 Made Labor Sa Pyridoxin-alpha-ketoglutarat

Also Published As

Publication number Publication date
JPS5782316A (en) 1982-05-22
IT1141070B (it) 1986-10-01
FR2490493B1 (fr) 1986-03-07
FR2490493A1 (fr) 1982-03-26
CA1177408A (en) 1984-11-06
DE3137125C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-04-06
NL8104357A (nl) 1982-04-16
SE8105561L (sv) 1982-03-23
US4361570A (en) 1982-11-30
IT8024827A0 (it) 1980-09-22
ZA816242B (en) 1982-08-25
SE459899B (sv) 1989-08-21
GB2084018A (en) 1982-04-07
BE890454A (fr) 1982-01-18
CH655009A5 (it) 1986-03-27

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: TUERK, D., DIPL.-CHEM. DR.RER.NAT. GILLE, C., DIPL

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee