DE3116250C2 - - Google Patents

Info

Publication number
DE3116250C2
DE3116250C2 DE3116250A DE3116250A DE3116250C2 DE 3116250 C2 DE3116250 C2 DE 3116250C2 DE 3116250 A DE3116250 A DE 3116250A DE 3116250 A DE3116250 A DE 3116250A DE 3116250 C2 DE3116250 C2 DE 3116250C2
Authority
DE
Germany
Prior art keywords
interferon
acid
mice
solution
oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3116250A
Other languages
German (de)
English (en)
Other versions
DE3116250A1 (de
Inventor
Yoshiyuki Saitama Jp Tahara
Hiroyasu Ageo Saitama Jp Koyama
Yasuhiro Niiza Saitama Jp Komatsu
Reiko Tokio/Tokyo Jp Kubota
Toshihiro Saitama Jp Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Publication of DE3116250A1 publication Critical patent/DE3116250A1/de
Application granted granted Critical
Publication of DE3116250C2 publication Critical patent/DE3116250C2/de
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE19813116250 1980-04-23 1981-04-23 "nonaprenylamin-derivate und sie enthaltende pharmazeutische mittel" Granted DE3116250A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5510880A JPS56150068A (en) 1980-04-23 1980-04-23 Nonaprenylamine derivative

Publications (2)

Publication Number Publication Date
DE3116250A1 DE3116250A1 (de) 1982-04-01
DE3116250C2 true DE3116250C2 (xx) 1988-12-22

Family

ID=12989550

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813116250 Granted DE3116250A1 (de) 1980-04-23 1981-04-23 "nonaprenylamin-derivate und sie enthaltende pharmazeutische mittel"

Country Status (6)

Country Link
US (2) US4755601A (xx)
JP (1) JPS56150068A (xx)
CA (1) CA1183136A (xx)
DE (1) DE3116250A1 (xx)
FR (1) FR2481281A1 (xx)
GB (1) GB2076395B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468458A (en) * 1980-01-12 1984-08-28 Eisai Co., Ltd. Two-functional-group-containing terpenoids, processes for the preparation of the same, and anti-ulcer agents containing the same
JPS56150068A (en) * 1980-04-23 1981-11-20 Nisshin Flour Milling Co Ltd Nonaprenylamine derivative
WO1998025617A1 (en) * 1996-12-13 1998-06-18 Merck & Co., Inc. Substituted aryl piperazines as modulators of chemokine receptor activity
CN110198932B (zh) * 2017-01-26 2023-04-07 东曹株式会社 烷醇胺、减摩剂、以及润滑油组合物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2590126A (en) * 1948-03-10 1952-03-25 Searle & Co Quaternary ammonium salts of 2, 6-lupetidine
BE520888A (xx) * 1952-06-26
US3268583A (en) * 1961-02-20 1966-08-23 Cumberland Chemical Corp Acetylenic amides
US3268524A (en) * 1961-02-20 1966-08-23 Cumberland Chemical Corp Process for the preparation of amines of the acetylenic series
US3232949A (en) * 1961-10-12 1966-02-01 Eastman Kodak Co Process of manufacturing branchedchain mono-olefinic aliphatic acids and intermediates therefor
GB1403851A (en) * 1973-01-03 1975-08-28 Pierrel Spa Isoprenoid amines
US4221810A (en) * 1978-03-23 1980-09-09 Nisshin Flour Milling Co., Ltd. Antiulcer compounds
CA1147752A (en) * 1979-05-04 1983-06-07 Yoshiyuki Tahara Isoprenylamines
JPS5673072A (en) * 1979-11-19 1981-06-17 Nisshin Flour Milling Co Ltd Decaprenylamine derivative
JPS5673046A (en) * 1979-11-19 1981-06-17 Nisshin Flour Milling Co Ltd Decaprenylamine derivative
US4271810A (en) * 1980-01-11 1981-06-09 General Motors Corporation Divided chamber engine with prechamber exhaust recirculation
US4324910A (en) * 1980-02-04 1982-04-13 Pennwalt Corporation Substituted urea compound containing 2,2,2-trichloro-1-hydroxyethyl group
JPS56150068A (en) * 1980-04-23 1981-11-20 Nisshin Flour Milling Co Ltd Nonaprenylamine derivative
GB2079395A (en) * 1980-06-27 1982-01-20 British Aluminium Co Ltd Clamp joint for panels

Also Published As

Publication number Publication date
GB2076395A (en) 1981-12-02
JPS56150068A (en) 1981-11-20
CA1183136A (en) 1985-02-26
US4857529A (en) 1989-08-15
FR2481281A1 (fr) 1981-10-30
DE3116250A1 (de) 1982-04-01
US4755601A (en) 1988-07-05
JPH0132826B2 (xx) 1989-07-10
GB2076395B (en) 1984-03-07
FR2481281B1 (xx) 1984-02-17

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: TUERK, D., DIPL.-CHEM. DR.RER.NAT. GILLE, C., DIPL

8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee