DE3071435D1 - Double-stranded dna which codes for a polypeptide with human fibroblast interferon activity, cloned dna, recombinant plasmid containing the dna and microorganism containing the recombinant plasmid - Google Patents

Double-stranded dna which codes for a polypeptide with human fibroblast interferon activity, cloned dna, recombinant plasmid containing the dna and microorganism containing the recombinant plasmid

Info

Publication number
DE3071435D1
DE3071435D1 DE8080106685T DE3071435T DE3071435D1 DE 3071435 D1 DE3071435 D1 DE 3071435D1 DE 8080106685 T DE8080106685 T DE 8080106685T DE 3071435 T DE3071435 T DE 3071435T DE 3071435 D1 DE3071435 D1 DE 3071435D1
Authority
DE
Germany
Prior art keywords
dna
recombinant plasmid
polypeptide
codes
double
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080106685T
Other languages
English (en)
Inventor
Haruo Sugano
Masami Muramatsu
Tadatsugu Taniguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japanese Foundation for Cancer Research
Original Assignee
Japanese Foundation for Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP13928979A external-priority patent/JPS5663996A/ja
Priority claimed from JP3393180A external-priority patent/JPS56131598A/ja
Application filed by Japanese Foundation for Cancer Research filed Critical Japanese Foundation for Cancer Research
Application granted granted Critical
Publication of DE3071435D1 publication Critical patent/DE3071435D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE8080106685T 1979-10-30 1980-10-30 Double-stranded dna which codes for a polypeptide with human fibroblast interferon activity, cloned dna, recombinant plasmid containing the dna and microorganism containing the recombinant plasmid Expired DE3071435D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13928979A JPS5663996A (en) 1979-10-30 1979-10-30 Novel recombinant having gene complementary to human interferon messenger rna
JP3393180A JPS56131598A (en) 1980-03-19 1980-03-19 Novel recombinant plasmid having gene of human fibroblastic interferon messenger rna

Publications (1)

Publication Number Publication Date
DE3071435D1 true DE3071435D1 (en) 1986-03-27

Family

ID=26372701

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080106685T Expired DE3071435D1 (en) 1979-10-30 1980-10-30 Double-stranded dna which codes for a polypeptide with human fibroblast interferon activity, cloned dna, recombinant plasmid containing the dna and microorganism containing the recombinant plasmid

Country Status (8)

Country Link
EP (1) EP0028033B1 (de)
AU (1) AU538665B2 (de)
CA (1) CA1341563C (de)
DE (1) DE3071435D1 (de)
DK (1) DK458480A (de)
ES (3) ES496426A0 (de)
IL (1) IL61366A (de)
NO (1) NO158950C (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510472A (en) * 1979-11-21 1996-04-23 Yeda Research And Development Co. Ltd. Production of recombinant human interferon-beta2
US5554513A (en) * 1979-11-21 1996-09-10 Yeda Research & Development Co. Ltd. Production of recombinant human interferon-beta2
DK170236B1 (da) * 1980-01-08 1995-07-10 Biogen Inc Rekombinante DNA-molekyler, fremgangsmåde til fremstilling af et polypeptid af IFN-alfa typen og fremgangsmåde til udvælgelse af DNA-sekvenser, der koder for polypeptider af IFN-alfa typen
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
DK33181A (da) * 1980-02-06 1981-08-07 Searle & Co Fremgangsmaade til fremstilling af et interferonlignende protein
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
DE3005843A1 (de) * 1980-02-16 1981-09-10 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
IL62552A0 (en) * 1980-04-03 1981-06-29 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
IL63916A0 (en) * 1980-09-25 1981-12-31 Genentech Inc Microbial production of human fibroblast interferon
EP0062971B1 (de) * 1981-03-27 1990-03-07 Imperial Chemical Industries Plc Genetisch modifizierte Mikroorganismen
IL65475A0 (en) * 1981-04-17 1982-07-30 Meloy Lab Production of immune interferon and its mrna
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
US5582824A (en) * 1981-10-19 1996-12-10 Genentech, Inc. Recombinant DES-CYS-TYR-CYS human immune interferon
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
US4450103A (en) * 1982-03-01 1984-05-22 Cetus Corporation Process for recovering human IFN-β from a transformed microorganism
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
DE3220116A1 (de) * 1982-05-28 1983-12-01 Dr. Karl Thomae Gmbh, 7950 Biberach Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung
US4588585A (en) * 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US4737462A (en) * 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
US5425940A (en) * 1986-04-09 1995-06-20 Cetus Oncology Corporation Combination therapy using interleukin-2 and tumor necrosis factor
EP0242329B1 (de) 1986-04-15 1995-07-19 Ciba-Geigy Ag Monoklonale Antikörper gegen Interferon-induziertes humanes Protein in gereignigter Form, und diese Antikörper enthaltende Testsätze
US4961969A (en) * 1987-05-11 1990-10-09 Cetus Corporation Process for recovering microbially produced interferon-β
DE4010797A1 (de) * 1990-04-04 1991-10-10 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
GB9506051D0 (en) 1995-03-24 1995-05-10 Univ Singapore Gene expression
KR100826621B1 (ko) 1997-09-23 2008-05-02 렌트슐러 비오테히놀로기 게엠베하 액상 인터페론-베타 제제
US20040010134A1 (en) 2000-04-12 2004-01-15 Rosen Craig A. Albumin fusion proteins
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
DK1463751T3 (da) 2001-12-21 2013-08-26 Human Genome Sciences Inc Albuminfusionsproteiner.
KR20080009111A (ko) 2005-04-11 2008-01-24 새비언트 파마수티컬즈 인크. 유레이트 옥시다아제의 변이형 및 이의 용도
PL2013225T3 (pl) 2006-04-12 2015-06-30 Crealta Pharmaceuticals Llc Oczyszczanie białek z zastosowaniem kationowego środka powierzchniowo czynnego
EP2207890A4 (de) 2007-10-05 2010-12-15 Barofold Inc Hochdruckbehandlung aggregierter interferone
PL398781A1 (pl) 2009-06-25 2012-11-19 Savient Pharmaceuticals, Inc. Sposoby i zestawy do prognozowania ryzyka wystapienia reakcji na wlew oraz zaniku odpowiedzi której posrednicza przeciwciala poprzez monitorowanie kwasu moczowego w surowicy podczas terapii z zastosowaniem pegylowanej urykazy
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta

Also Published As

Publication number Publication date
ES8303530A1 (es) 1983-02-01
EP0028033A3 (en) 1981-08-19
ES507595A0 (es) 1983-02-01
EP0028033A2 (de) 1981-05-06
NO803230L (no) 1981-05-04
ES8203102A1 (es) 1982-02-16
EP0028033B1 (de) 1986-02-19
IL61366A0 (en) 1980-12-31
CA1341563C (en) 2007-12-04
ES496426A0 (es) 1982-02-16
NO158950C (no) 1988-11-16
NO158950B (no) 1988-08-08
AU538665B2 (en) 1984-08-23
ES8303529A1 (es) 1983-02-01
AU6376280A (en) 1981-05-07
ES507596A0 (es) 1983-02-01
DK458480A (da) 1981-05-01
IL61366A (en) 1983-11-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition