ES8303529A1 - Un procedimiento para la produccion de un plasmido recombi- nante. - Google Patents
Un procedimiento para la produccion de un plasmido recombi- nante.Info
- Publication number
- ES8303529A1 ES8303529A1 ES507595A ES507595A ES8303529A1 ES 8303529 A1 ES8303529 A1 ES 8303529A1 ES 507595 A ES507595 A ES 507595A ES 507595 A ES507595 A ES 507595A ES 8303529 A1 ES8303529 A1 ES 8303529A1
- Authority
- ES
- Spain
- Prior art keywords
- dna
- recombinant plasmid
- polypeptide
- codes
- double
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE UN PLASMIDO RECOMBINANTE. CONSISTE EN INSERTAR UN ADN QUE MUESTRA COMPLEMENTARIEDAD CON EL ARN MENSAJERO DE INTERFERON DE FIBROBLASTO HUMANO EN UN ADN RECTOR QUE ES UN PLASMIDO DE ESCHERICHIA COLI T<PIF 319-13. LA INSERCION SE LLEVA A CABO SIGUIENDO METODOS CONVENCIONALES. ESTOS PRODUCTOS TIENEN APLICACIONES FARMACOLOGICAS DEBIDO A SU ACTIVIDAD ANTIVIRAL Y ANTITUMORAL.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13928979A JPS5663996A (en) | 1979-10-30 | 1979-10-30 | Novel recombinant having gene complementary to human interferon messenger rna |
JP3393180A JPS56131598A (en) | 1980-03-19 | 1980-03-19 | Novel recombinant plasmid having gene of human fibroblastic interferon messenger rna |
Publications (2)
Publication Number | Publication Date |
---|---|
ES507595A0 ES507595A0 (es) | 1983-02-01 |
ES8303529A1 true ES8303529A1 (es) | 1983-02-01 |
Family
ID=26372701
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES496426A Expired ES8203102A1 (es) | 1979-10-30 | 1980-10-30 | Un procedimiento para la preparacion de un adn que codifica un polipeptido con actividad de interferon. |
ES507596A Expired ES8303530A1 (es) | 1979-10-30 | 1981-11-30 | Un procedimiento para la preparacion de un microorganismo que contiene un plasmido recombinante de un adn |
ES507595A Expired ES8303529A1 (es) | 1979-10-30 | 1981-11-30 | Un procedimiento para la produccion de un plasmido recombi- nante. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES496426A Expired ES8203102A1 (es) | 1979-10-30 | 1980-10-30 | Un procedimiento para la preparacion de un adn que codifica un polipeptido con actividad de interferon. |
ES507596A Expired ES8303530A1 (es) | 1979-10-30 | 1981-11-30 | Un procedimiento para la preparacion de un microorganismo que contiene un plasmido recombinante de un adn |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0028033B1 (es) |
AU (1) | AU538665B2 (es) |
CA (1) | CA1341563C (es) |
DE (1) | DE3071435D1 (es) |
DK (1) | DK458480A (es) |
ES (3) | ES8203102A1 (es) |
IL (1) | IL61366A (es) |
NO (1) | NO158950C (es) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5554513A (en) * | 1979-11-21 | 1996-09-10 | Yeda Research & Development Co. Ltd. | Production of recombinant human interferon-beta2 |
US5510472A (en) * | 1979-11-21 | 1996-04-23 | Yeda Research And Development Co. Ltd. | Production of recombinant human interferon-beta2 |
IE54096B1 (en) * | 1980-01-08 | 1989-06-21 | Biogen Nv | Dn sequences, recombinant dna molecules and processes for producing human interferon - like polypeptides |
US6835557B1 (en) | 1980-01-08 | 2004-12-28 | Biogen, Inc. | DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides |
DK33181A (da) * | 1980-02-06 | 1981-08-07 | Searle & Co | Fremgangsmaade til fremstilling af et interferonlignende protein |
DE3005843A1 (de) * | 1980-02-16 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus |
DE3005897A1 (de) * | 1980-02-16 | 1981-09-03 | Hoechst Ag, 6000 Frankfurt | Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus |
ES8302096A1 (es) | 1980-04-03 | 1982-12-16 | Biogen Nv | Un metodo de producir un polipeptido que muestra una actividad immunologica obiologica de interferon de fibroblasto hu- mano. |
NZ198445A (en) * | 1980-09-25 | 1984-05-31 | Genentech Inc | Production of human fibroblast interferon by recombinant dna technology |
DE3280127D1 (de) * | 1981-03-27 | 1990-04-12 | Ici Plc | Genetisch modifizierte mikroorganismen. |
IL65475A0 (en) * | 1981-04-17 | 1982-07-30 | Meloy Lab | Production of immune interferon and its mrna |
GB2108510B (en) * | 1981-10-03 | 1984-12-12 | Ciba Geigy Ag | Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof |
AU561343B2 (en) * | 1981-10-19 | 1987-05-07 | Genentech Inc. | Human immune interferon by recombinant dna |
US5582824A (en) * | 1981-10-19 | 1996-12-10 | Genentech, Inc. | Recombinant DES-CYS-TYR-CYS human immune interferon |
US4450103A (en) * | 1982-03-01 | 1984-05-22 | Cetus Corporation | Process for recovering human IFN-β from a transformed microorganism |
US5827694A (en) * | 1982-03-08 | 1998-10-27 | Genentech, Inc. | DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides |
US6936694B1 (en) | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
DE3220116A1 (de) * | 1982-05-28 | 1983-12-01 | Dr. Karl Thomae Gmbh, 7950 Biberach | Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung |
US4737462A (en) * | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
US4588585A (en) * | 1982-10-19 | 1986-05-13 | Cetus Corporation | Human recombinant cysteine depleted interferon-β muteins |
US5831023A (en) * | 1982-11-01 | 1998-11-03 | Genentech, Inc. | Recombinant animal interferon polypeptides |
US4518584A (en) * | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
US4855238A (en) * | 1983-12-16 | 1989-08-08 | Genentech, Inc. | Recombinant gamma interferons having enhanced stability and methods therefor |
US5425940A (en) * | 1986-04-09 | 1995-06-20 | Cetus Oncology Corporation | Combination therapy using interleukin-2 and tumor necrosis factor |
ATE125304T1 (de) | 1986-04-15 | 1995-08-15 | Ciba Geigy Ag | Monoklonale antikörper gegen interferon- induziertes humanes protein in gereignigter form, und diese antikörper enthaltende testsätze. |
US4961969A (en) * | 1987-05-11 | 1990-10-09 | Cetus Corporation | Process for recovering microbially produced interferon-β |
DE4010797A1 (de) * | 1990-04-04 | 1991-10-10 | Hoechst Ag | Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
GB9506051D0 (en) | 1995-03-24 | 1995-05-10 | Univ Singapore | Gene expression |
CA2304808C (en) | 1997-09-23 | 2011-03-22 | Michael Tschope | Liquid interferon-.beta. formulations |
AU2001266557A1 (en) | 2000-04-12 | 2001-10-23 | Human Genome Sciences, Inc. | Albumin fusion proteins |
US6887462B2 (en) | 2001-04-09 | 2005-05-03 | Chiron Corporation | HSA-free formulations of interferon-beta |
EP2261250B1 (en) | 2001-12-21 | 2015-07-01 | Human Genome Sciences, Inc. | GCSF-Albumin fusion proteins |
US9534013B2 (en) | 2006-04-12 | 2017-01-03 | Horizon Pharma Rheumatology Llc | Purification of proteins with cationic surfactant |
CA2604399A1 (en) | 2005-04-11 | 2006-10-19 | Savient Pharmaceuticals, Inc. | Variant forms of urate oxidase and use thereof |
EP2207890A4 (en) | 2007-10-05 | 2010-12-15 | Barofold Inc | HIGH PRESSURE PROCESSING OF AGGREGATED INTERFERONS |
KR101861547B1 (ko) | 2009-06-25 | 2018-07-02 | 크레알타 파마슈티칼스 엘엘씨 | 페길화된 유리카아제 치료 중에 혈청 요산을 모니터링하여 주입 반응의 위험성 및 반응의 항체매개 상실을 예측하는 방법 및 키트 |
DE102009032179A1 (de) | 2009-07-07 | 2011-01-13 | Biogenerix Ag | Verfahren zur Reinigung von Interferon beta |
-
1980
- 1980-10-28 AU AU63762/80A patent/AU538665B2/en not_active Expired
- 1980-10-29 IL IL61366A patent/IL61366A/xx unknown
- 1980-10-29 NO NO803230A patent/NO158950C/no unknown
- 1980-10-29 DK DK458480A patent/DK458480A/da not_active Application Discontinuation
- 1980-10-30 EP EP80106685A patent/EP0028033B1/en not_active Expired
- 1980-10-30 ES ES496426A patent/ES8203102A1/es not_active Expired
- 1980-10-30 DE DE8080106685T patent/DE3071435D1/de not_active Expired
- 1980-10-30 CA CA000363628A patent/CA1341563C/en active Active
-
1981
- 1981-11-30 ES ES507596A patent/ES8303530A1/es not_active Expired
- 1981-11-30 ES ES507595A patent/ES8303529A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES496426A0 (es) | 1982-02-16 |
EP0028033B1 (en) | 1986-02-19 |
ES507596A0 (es) | 1983-02-01 |
AU6376280A (en) | 1981-05-07 |
IL61366A (en) | 1983-11-30 |
NO158950C (no) | 1988-11-16 |
ES507595A0 (es) | 1983-02-01 |
CA1341563C (en) | 2007-12-04 |
AU538665B2 (en) | 1984-08-23 |
DK458480A (da) | 1981-05-01 |
IL61366A0 (en) | 1980-12-31 |
EP0028033A3 (en) | 1981-08-19 |
DE3071435D1 (en) | 1986-03-27 |
EP0028033A2 (en) | 1981-05-06 |
ES8303530A1 (es) | 1983-02-01 |
ES8203102A1 (es) | 1982-02-16 |
NO803230L (no) | 1981-05-04 |
NO158950B (no) | 1988-08-08 |
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