ES8506194A1 - Polipeptido de interferon- humano - Google Patents

Polipeptido de interferon- humano

Info

Publication number
ES8506194A1
ES8506194A1 ES530597A ES530597A ES8506194A1 ES 8506194 A1 ES8506194 A1 ES 8506194A1 ES 530597 A ES530597 A ES 530597A ES 530597 A ES530597 A ES 530597A ES 8506194 A1 ES8506194 A1 ES 8506194A1
Authority
ES
Spain
Prior art keywords
human interferon
gamma polypeptide
novel human
polypeptide
gamma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530597A
Other languages
English (en)
Other versions
ES530597A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japanese Foundation for Cancer Research
KH Neochem Co Ltd
Original Assignee
Japanese Foundation for Cancer Research
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26381690&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8506194(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Japanese Foundation for Cancer Research, Kyowa Hakko Kogyo Co Ltd filed Critical Japanese Foundation for Cancer Research
Publication of ES530597A0 publication Critical patent/ES530597A0/es
Publication of ES8506194A1 publication Critical patent/ES8506194A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PRODUCIR POLIPEPTIDO DE INTERFERON-G HUMANO.COMPRENDE CULTIVAR A UN PH 5,5-8,5 Y A UNA TEMPERATURA DE 18-40JC UN MICROORGANISMO QUE PERTENECE A ESCHERICHIA COLI TRANSFORMADO CON UN PLASMIDO RECOMBINANTE QUE SE PREPARA A PARTIR DE PKYP Y PIFNG-64 DONDE SE INCORPORA LINEA ABAJO DE UN PROMOTOR DE TRIPTOFANO UN FRAGMENTO DE DNA CODIFICANTE DE POLIPEPTIDO DE INTERFERON-G HUMANO EN UN MEDIO; ACUMULAR POLIPEPTIDO DE INTERFERON-G HUMANO EN EL MEDIO DE CULTIVO Y RECUPERAR DE ESTE EL POLIPEPTIDO DE INTERFERON-G HUMANO.
ES530597A 1983-03-14 1984-03-14 Polipeptido de interferon- humano Expired ES8506194A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58042042A JPH0740925B2 (ja) 1983-03-14 1983-03-14 新規ヒトインタ−フエロン−γポリペプチド
JP4207840A JPH05320200A (ja) 1983-03-14 1992-08-04 新規ヒトインターフェロン−γポリペプチド

Publications (2)

Publication Number Publication Date
ES530597A0 ES530597A0 (es) 1985-07-01
ES8506194A1 true ES8506194A1 (es) 1985-07-01

Family

ID=26381690

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530597A Expired ES8506194A1 (es) 1983-03-14 1984-03-14 Polipeptido de interferon- humano

Country Status (6)

Country Link
EP (1) EP0121157B1 (es)
JP (2) JPH0740925B2 (es)
AU (1) AU2561984A (es)
DK (1) DK160945C (es)
ES (1) ES8506194A1 (es)
NO (1) NO169020C (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5582824A (en) * 1981-10-19 1996-12-10 Genentech, Inc. Recombinant DES-CYS-TYR-CYS human immune interferon
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
ZA846554B (en) * 1983-09-20 1985-04-24 Hoffmann La Roche Immune interferon and method for its purification
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
MX9203641A (es) * 1983-12-16 1992-07-01 Genentech Inc Interferones gamma recombinantes que poseen estabilidad mejorada y metodos biotecnologicos para su obtencion.
SK8292002A3 (en) 1999-11-12 2002-12-03 Maxygen Holdings Ltd A conjugate exhibiting interferon gamma activity, nucleotide sequence encoding for a polypeptide fraction of conjugate, an expression vector and a host cell containing nucleotide sequence, pharmaceutical composition comprising the same and use thereof
CN1309423C (zh) 1999-11-12 2007-04-11 马克西根控股公司 干扰素γ偶联物
US6958388B2 (en) 2001-04-06 2005-10-25 Maxygen, Aps Interferon gamma polypeptide variants
US7038015B2 (en) 2001-04-06 2006-05-02 Maxygen Holdings, Ltd. Interferon gamma polypeptide variants
EP1539814A2 (en) 2002-07-03 2005-06-15 Maxygen Holdings Ltd. c/o Close Brothers (Cayman) Limited Full-length interferon gamma polypeptide variants
US9676820B2 (en) 2013-04-10 2017-06-13 National University Corporation Hamamatsu University School Of Medicine Method for inhibiting proliferation of high LIX1L-expressing tumor cell, and tumor cell proliferation-inhibiting peptide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65475A0 (en) * 1981-04-17 1982-07-30 Meloy Lab Production of immune interferon and its mrna
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
JPS58110548A (ja) * 1981-12-24 1983-07-01 Asahi Chem Ind Co Ltd 新規な生理活性ペプチド
JPS58110600A (ja) * 1981-12-25 1983-07-01 Kyowa Hakko Kogyo Co Ltd ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド
EP0088540A3 (en) * 1982-02-22 1984-10-17 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing human immune interferon-like polypeptides
IL68100A0 (en) * 1982-03-24 1983-06-15 Takeda Chemical Industries Ltd Novel dna and use thereof
JPH0787797B2 (ja) * 1982-05-20 1995-09-27 サントリー株式会社 ヒト・ガンマ・インタ−フエロン様ポリペプチドの製造法
US4582800A (en) * 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression
IL69851A0 (en) * 1982-09-30 1983-12-30 Japan Found Cancer Novel dna and recombinant plasmid containing the same

Also Published As

Publication number Publication date
NO840952L (no) 1984-09-17
ES530597A0 (es) 1985-07-01
DK155184D0 (da) 1984-03-13
AU2561984A (en) 1984-09-20
DK160945B (da) 1991-05-06
JPS59167596A (ja) 1984-09-21
DK160945C (da) 1991-10-21
JPH0740925B2 (ja) 1995-05-10
DK155184A (da) 1984-09-15
EP0121157A1 (en) 1984-10-10
NO169020C (no) 1992-04-29
EP0121157B1 (en) 1989-06-14
JPH05320200A (ja) 1993-12-03
NO169020B (no) 1992-01-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000403