DE2967306D1 - New propanone derivatives, process for producing thereof and pharmaceutical compositions containing these derivatives as active ingredients - Google Patents

New propanone derivatives, process for producing thereof and pharmaceutical compositions containing these derivatives as active ingredients

Info

Publication number
DE2967306D1
DE2967306D1 DE7979100528T DE2967306T DE2967306D1 DE 2967306 D1 DE2967306 D1 DE 2967306D1 DE 7979100528 T DE7979100528 T DE 7979100528T DE 2967306 T DE2967306 T DE 2967306T DE 2967306 D1 DE2967306 D1 DE 2967306D1
Authority
DE
Germany
Prior art keywords
derivatives
producing
new
pharmaceutical compositions
active ingredients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979100528T
Other languages
English (en)
Inventor
Akihide Kohda
Teikichi Kurosaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Zoki Pharmaceutical Co Ltd
Original Assignee
Nippon Zoki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11995644&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE2967306(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nippon Zoki Pharmaceutical Co Ltd filed Critical Nippon Zoki Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE2967306D1 publication Critical patent/DE2967306D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE7979100528T 1978-02-22 1979-02-22 New propanone derivatives, process for producing thereof and pharmaceutical compositions containing these derivatives as active ingredients Expired DE2967306D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1930378A JPS54125630A (en) 1978-02-22 1978-02-22 Novel propanone derivative*its manufacture and medical composition containing it as active component

Publications (1)

Publication Number Publication Date
DE2967306D1 true DE2967306D1 (en) 1985-01-10

Family

ID=11995644

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979100528T Expired DE2967306D1 (en) 1978-02-22 1979-02-22 New propanone derivatives, process for producing thereof and pharmaceutical compositions containing these derivatives as active ingredients

Country Status (17)

Country Link
US (2) US4277474A (de)
EP (1) EP0004000B2 (de)
JP (1) JPS54125630A (de)
AR (1) AR221080A1 (de)
AT (1) AT372086B (de)
AU (1) AU530412B2 (de)
BR (1) BR7901124A (de)
CA (1) CA1120487A (de)
DE (1) DE2967306D1 (de)
DK (1) DK77679A (de)
ES (1) ES477882A1 (de)
IL (1) IL56664A (de)
MX (1) MX5399E (de)
NZ (1) NZ189721A (de)
PH (1) PH15114A (de)
SU (1) SU873873A3 (de)
ZA (1) ZA79778B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS184021B1 (en) * 1973-07-19 1978-07-31 Jan Drkal Rolling machine for cross tapered rolling
DE3019497A1 (de) * 1980-05-22 1981-11-26 Bayer Ag, 5090 Leverkusen Aminopropiophenon-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
JPS5944371A (ja) * 1982-09-07 1984-03-12 Dainippon Pharmaceut Co Ltd １―フエニル―２―メチル―３―（１―ピロリジニル）―１―プロパノン誘導体
JPS59190980A (ja) * 1983-04-15 1984-10-29 Hokuriku Seiyaku Co Ltd ２’−クロロ−３−アミノ−２−メチル置換プロピオフエノン誘導体
JPS59190981A (ja) * 1983-04-15 1984-10-29 Hokuriku Seiyaku Co Ltd ３−ピロリジノ置換プロピオフエノン誘導体
HU33131A (de) * 1984-01-26 1984-10-29
NL8400508A (nl) * 1984-02-17 1985-09-16 Philips Nv Audiotransmissiecircuit met als lijnspanningsstabilisator uitgevoerde zendversterker.
DE3436450A1 (de) * 1984-10-05 1986-04-10 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von p-aminoethylketonen
US5057535A (en) * 1985-04-11 1991-10-15 Nippon Kayaku Kabushiki Kaisha Derivatives of an aminoketone
DE3688917T2 (de) * 1985-04-11 1994-02-10 Nippon Kayaku Kk Derivate eines Aminoketons.
US5103022A (en) * 1985-04-11 1992-04-07 Nippon Kayaku Kabushiki Kaisha Process for producing an optically active aminoketone derivative
US4650692A (en) * 1985-11-01 1987-03-17 Ashland Oil, Inc. Metal-sulfonate/piperidine derivative combination protective coatings
JPH03115267A (ja) * 1989-09-28 1991-05-16 Maruho Kk プロピオフエノン誘導体、その製造方法、それを含む中枢性筋弛緩剤および抗痙攣剤
AU8242598A (en) * 1997-07-18 1999-02-10 Nippon Kayaku Kabushiki Kaisha Aromatic ketone derivatives and uses thereof
WO1999045914A1 (fr) * 1998-03-13 1999-09-16 Maruho Kabushikikaisha Derive alkylamine et agent anesthesique utilisant ce derive
GB9808447D0 (en) 1998-04-18 1998-06-17 Zeneca Ltd Process
CN1869002A (zh) * 2005-05-27 2006-11-29 中国科学院上海药物研究所 一类非甾体雄激素受体调节剂、其制备方法和用途
MX2008014450A (es) 2006-05-18 2009-03-09 Mannkind Corp Inhibidores de cinasa intracelular.
ES2601856T3 (es) * 2007-06-08 2017-02-16 Mannkind Corporation Inhibidores de la IRE-1A
CN109310650A (zh) * 2016-05-13 2019-02-05 纽约市哥伦比亚大学理事会 用于减少过表达c-myc的癌症中的c-myc的化合物
IT201600098338A1 (it) * 2016-09-30 2018-03-30 Univ Degli Studi Padova Composti 1-fenilpropanone e loro impiego

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2282907A (en) * 1941-05-01 1942-05-12 Us Rubber Co Parasiticide
US2771391A (en) * 1953-08-20 1956-11-20 Allied Lab Inc Physiologically active p-alkoxy-beta-piperidinopropiophenones causing cns depressantand anesthetic effects in animals
NL283900A (de) * 1960-04-26
FR1301863A (fr) * 1961-06-29 1962-08-24 Science Union & Cie Aminocétones substituées et leurs procédés de préparation
US3151124A (en) * 1961-11-20 1964-09-29 Ciba Geigy Corp Alpha oxy-beta alkyl-gamma tertiary amino-alpha phenyl propanes
GB1142474A (en) * 1965-03-24 1969-02-05 Ferrosan Ab Production of piperidino-butyrophenones
GB1115992A (en) * 1965-03-26 1968-06-06 Lafon Labor Improvements in or relating to n-piperidino-alkoxyacetophenones
US3417087A (en) * 1965-12-27 1968-12-17 Research Corp 3(aminopropionyl)benzothiophenes
US3903092A (en) * 1966-03-02 1975-09-02 Aspro Nicholas Ltd 2-Tertiaryamino-1-(benzo{8 b{9 thienyl)ethanols
US3495015A (en) * 1967-11-17 1970-02-10 American Cyanamid Co Treatment of depression with 3-substituted amino-2-phenylpropiophenones
GB1213963A (en) * 1968-03-28 1970-11-25 Richter Gedeon Vegyeszet Aromatic amino ketones
US3637712A (en) * 1970-01-26 1972-01-25 Bristol Myers Co Piperidylpropanol compounds
FR2138488A1 (en) * 1971-05-27 1973-01-05 Lipha 1-(5-indanyl)-omega-aminoalkanes - with tranquillizing activity
FR2150594A1 (en) * 1971-08-27 1973-04-13 Delalande Sa Omega-amino-1,2-diphenyl-1-alkanones - with analgesic antiinflammatory anti-ulcer,bronchodilator,spasmolytic and hypotensive
HU166289B (de) * 1973-01-15 1975-02-28
JPS5527914B2 (de) * 1973-12-14 1980-07-24
US3995047A (en) * 1973-12-14 1976-11-30 Eisai Co., Ltd. Propiophenone derivatives in the treatment of pathological muscular conditions
FR2305981A1 (fr) * 1975-04-03 1976-10-29 Innothera Lab Sa Nouvelles benzothienyl aminoethyl cetones, leur procede de preparation et leur application en therapeutique
DD124521A1 (de) * 1976-03-16 1977-03-02

Also Published As

Publication number Publication date
EP0004000B2 (de) 1988-06-15
AU4451779A (en) 1979-08-30
JPS54125630A (en) 1979-09-29
SU873873A3 (ru) 1981-10-15
MX5399E (es) 1983-07-12
US4563454A (en) 1986-01-07
BR7901124A (pt) 1979-09-11
ATA133279A (de) 1983-01-15
IL56664A (en) 1984-01-31
EP0004000B1 (de) 1984-11-28
EP0004000A1 (de) 1979-09-19
IL56664A0 (en) 1979-05-31
AU530412B2 (en) 1983-07-14
PH15114A (en) 1982-08-10
ES477882A1 (es) 1979-10-16
DK77679A (da) 1979-08-23
CA1120487A (en) 1982-03-23
NZ189721A (en) 1981-11-19
AR221080A1 (es) 1980-12-30
US4277474A (en) 1981-07-07
ZA79778B (en) 1980-03-26
JPS6256143B2 (de) 1987-11-24
AT372086B (de) 1983-08-25

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8339 Ceased/non-payment of the annual fee