DE2926463C2 - - Google Patents

Info

Publication number
DE2926463C2
DE2926463C2 DE2926463A DE2926463A DE2926463C2 DE 2926463 C2 DE2926463 C2 DE 2926463C2 DE 2926463 A DE2926463 A DE 2926463A DE 2926463 A DE2926463 A DE 2926463A DE 2926463 C2 DE2926463 C2 DE 2926463C2
Authority
DE
Germany
Prior art keywords
glucoside
diosgenin
hecogenin
compounds
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2926463A
Other languages
German (de)
English (en)
Other versions
DE2926463A1 (de
Inventor
Karl Heinrich Dr. Durban Natal Za Pegel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HOYER GMBH & CO KG, 41469 NEUSS, DE
Original Assignee
Roecar Holdings (netherlands Antilles) Nv Willemstad Curacao Niederlaendische Antillen Nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roecar Holdings (netherlands Antilles) Nv Willemstad Curacao Niederlaendische Antillen Nl filed Critical Roecar Holdings (netherlands Antilles) Nv Willemstad Curacao Niederlaendische Antillen Nl
Publication of DE2926463A1 publication Critical patent/DE2926463A1/de
Application granted granted Critical
Publication of DE2926463C2 publication Critical patent/DE2926463C2/de
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE19792926463 1978-07-05 1979-06-30 Spiroketaline und ihre verwendung Granted DE2926463A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7828935 1978-07-05

Publications (2)

Publication Number Publication Date
DE2926463A1 DE2926463A1 (de) 1980-01-24
DE2926463C2 true DE2926463C2 (US06826419-20041130-M00005.png) 1988-08-11

Family

ID=10498274

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19792926463 Granted DE2926463A1 (de) 1978-07-05 1979-06-30 Spiroketaline und ihre verwendung

Country Status (19)

Country Link
US (1) US4265886A (US06826419-20041130-M00005.png)
JP (1) JPS5536471A (US06826419-20041130-M00005.png)
AU (1) AU550621B2 (US06826419-20041130-M00005.png)
BE (1) BE877511A (US06826419-20041130-M00005.png)
CA (1) CA1140857A (US06826419-20041130-M00005.png)
CH (1) CH641678A5 (US06826419-20041130-M00005.png)
DE (1) DE2926463A1 (US06826419-20041130-M00005.png)
DK (1) DK283579A (US06826419-20041130-M00005.png)
ES (1) ES8101624A1 (US06826419-20041130-M00005.png)
FR (1) FR2430233A1 (US06826419-20041130-M00005.png)
IL (1) IL57729A (US06826419-20041130-M00005.png)
IT (1) IT1116894B (US06826419-20041130-M00005.png)
LU (1) LU81467A1 (US06826419-20041130-M00005.png)
NL (1) NL7905258A (US06826419-20041130-M00005.png)
NZ (1) NZ190925A (US06826419-20041130-M00005.png)
PT (1) PT69875A (US06826419-20041130-M00005.png)
SE (1) SE7905810L (US06826419-20041130-M00005.png)
YU (1) YU41343B (US06826419-20041130-M00005.png)
ZA (1) ZA793320B (US06826419-20041130-M00005.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5855500A (ja) * 1981-09-25 1983-04-01 Tokiwa Yakuhin Kogyo Kk 16−デヒドロプレグネノロンの製造法
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia
DE3829641A1 (de) * 1988-09-01 1990-03-15 Roecar Holdings Nv Transdermal anwendbare pharmazeutische zubereitungen mit sterolinen und/oder spiroketalinen
DE3838716A1 (de) * 1988-11-15 1990-05-17 Kanoldt Arzneimittel Gmbh Arzneimittelzubereitung aus esterderivaten des hecogenins und dessen verwendung zur behandlung von benigner prostatahyperplasie
CZ331094A3 (en) * 1992-06-26 1995-09-13 Pfizer Steroidal glycosides and their use for treating hypercholesterolemia and atherosclerosis
CN1121722A (zh) * 1993-04-28 1996-05-01 美国辉瑞有限公司 螺甾烷基苷结晶-水合物
US5502038A (en) * 1993-06-21 1996-03-26 Medical Research Foundation Of Oregon Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption
AU7948494A (en) * 1993-12-28 1995-07-17 Pfizer Inc. Steroidal glycosides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2395339A (en) * 1941-05-15 1946-02-19 Parke Davis & Co Sapogenin derivatives and preparation of same
US3446751A (en) * 1965-11-29 1969-05-27 Brunswick Corp Hemolyzing composition
DE2027949A1 (de) * 1970-06-06 1971-12-16 Farbwerke Hoechst AG, vorm. Meister Lucius & Brüning, 6000 Frankfurt Verfahren zur Herstellung von Steroidglykosiden
GB1380253A (en) * 1971-01-21 1975-01-08 Inverni Della Beffa Spa Prosapogenins
DE2759171A1 (de) * 1977-12-31 1979-07-12 Roecar Holdings Nv Arzneimittel mit wirkung als prostaglandinsynthetaseninhibitor

Also Published As

Publication number Publication date
IL57729A0 (en) 1979-11-30
NL7905258A (nl) 1980-01-08
US4265886A (en) 1981-05-05
AU550621B2 (en) 1986-03-27
IT7949665A0 (it) 1979-07-05
NZ190925A (en) 1985-05-31
AU4865179A (en) 1980-02-07
SE7905810L (sv) 1980-01-06
LU81467A1 (fr) 1979-10-30
FR2430233A1 (fr) 1980-02-01
IT1116894B (it) 1986-02-10
PT69875A (en) 1979-08-01
IL57729A (en) 1983-07-31
CA1140857A (en) 1983-02-08
JPS5536471A (en) 1980-03-14
DK283579A (da) 1980-01-06
ZA793320B (en) 1980-09-24
FR2430233B1 (US06826419-20041130-M00005.png) 1983-05-20
ES482253A0 (es) 1980-12-16
CH641678A5 (de) 1984-03-15
YU163879A (en) 1983-02-28
DE2926463A1 (de) 1980-01-24
YU41343B (en) 1987-02-28
BE877511A (fr) 1979-11-05
ES8101624A1 (es) 1980-12-16

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: HARMSEN, H., DR. UTESCHER, W., DR. HARMSEN, P., DI

D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HOYER GMBH & CO KG, 41469 NEUSS, DE

8339 Ceased/non-payment of the annual fee