DE2900926A1 - Therapeutisch wirksame pseudopeptide, diese enthaltende zusammensetzungen und verfahren zu deren herstellung - Google Patents

Therapeutisch wirksame pseudopeptide, diese enthaltende zusammensetzungen und verfahren zu deren herstellung

Info

Publication number
DE2900926A1
DE2900926A1 DE19792900926 DE2900926A DE2900926A1 DE 2900926 A1 DE2900926 A1 DE 2900926A1 DE 19792900926 DE19792900926 DE 19792900926 DE 2900926 A DE2900926 A DE 2900926A DE 2900926 A1 DE2900926 A1 DE 2900926A1
Authority
DE
Germany
Prior art keywords
leu
pseudopeptide
amino acid
arg
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19792900926
Other languages
German (de)
English (en)
Other versions
DE2900926C2 (fr
Inventor
Kam-Fook Fok
John Allen Yankeelov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Corp
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of DE2900926A1 publication Critical patent/DE2900926A1/de
Application granted granted Critical
Publication of DE2900926C2 publication Critical patent/DE2900926C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/16—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE19792900926 1978-01-11 1979-01-11 Therapeutisch wirksame pseudopeptide, diese enthaltende zusammensetzungen und verfahren zu deren herstellung Granted DE2900926A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86862678A 1978-01-11 1978-01-11
US96210078A 1978-11-20 1978-11-20

Publications (2)

Publication Number Publication Date
DE2900926A1 true DE2900926A1 (de) 1979-07-19
DE2900926C2 DE2900926C2 (fr) 1991-01-17

Family

ID=27128063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19792900926 Granted DE2900926A1 (de) 1978-01-11 1979-01-11 Therapeutisch wirksame pseudopeptide, diese enthaltende zusammensetzungen und verfahren zu deren herstellung

Country Status (5)

Country Link
CA (1) CA1180006A (fr)
CH (1) CH641441A5 (fr)
DE (1) DE2900926A1 (fr)
FR (1) FR2414498A1 (fr)
GB (1) GB2013210B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1463865A (fr) * 1964-07-27 1966-07-22 Ceskoslovenska Akademie Ved Procédé pour la préparation des dérivés cycliques de peptides ainsi que les produits conformes à ceux obtenus par le présent procédé ou procédé similaire

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Biochem. Biophys. Res. Comm., 74, 1977, S. 273-278 *

Also Published As

Publication number Publication date
CH641441A5 (de) 1984-02-29
GB2013210B (en) 1982-04-28
FR2414498A1 (fr) 1979-08-10
DE2900926C2 (fr) 1991-01-17
CA1180006A (fr) 1984-12-27
FR2414498B1 (fr) 1982-08-27
GB2013210A (en) 1979-08-08

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee