DE2818290A1 - Neue naphthyridine - Google Patents

Neue naphthyridine

Info

Publication number
DE2818290A1
DE2818290A1 DE19782818290 DE2818290A DE2818290A1 DE 2818290 A1 DE2818290 A1 DE 2818290A1 DE 19782818290 DE19782818290 DE 19782818290 DE 2818290 A DE2818290 A DE 2818290A DE 2818290 A1 DE2818290 A1 DE 2818290A1
Authority
DE
Germany
Prior art keywords
compounds according
alkyl
formula
compounds
naphthyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19782818290
Other languages
German (de)
English (en)
Inventor
John James Baldwin
Gerald Salvatore Ponticello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2818290A1 publication Critical patent/DE2818290A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19782818290 1977-05-02 1978-04-26 Neue naphthyridine Ceased DE2818290A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79275277A 1977-05-02 1977-05-02

Publications (1)

Publication Number Publication Date
DE2818290A1 true DE2818290A1 (de) 1978-11-09

Family

ID=25157956

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782818290 Ceased DE2818290A1 (de) 1977-05-02 1978-04-26 Neue naphthyridine

Country Status (12)

Country Link
JP (1) JPS53136000A (US06291489-20010918-C00077.png)
BE (1) BE866544A (US06291489-20010918-C00077.png)
CH (1) CH634320A5 (US06291489-20010918-C00077.png)
DE (1) DE2818290A1 (US06291489-20010918-C00077.png)
DK (1) DK166478A (US06291489-20010918-C00077.png)
FR (1) FR2389624B1 (US06291489-20010918-C00077.png)
GB (1) GB1566693A (US06291489-20010918-C00077.png)
IE (1) IE46874B1 (US06291489-20010918-C00077.png)
IT (1) IT1107210B (US06291489-20010918-C00077.png)
LU (1) LU79551A1 (US06291489-20010918-C00077.png)
NL (1) NL7804168A (US06291489-20010918-C00077.png)
SE (1) SE7804318L (US06291489-20010918-C00077.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004352A1 (fr) * 1978-03-16 1979-10-03 Firmenich Sa Composés azotés bicycliques et leur utilisation en tant qu'ingrédients aromatisants

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0059291B1 (en) * 1981-02-27 1985-03-27 American Home Products Corporation Antihypertensive agents
AU634561B2 (en) * 1989-07-27 1993-02-25 Eli Lilly And Company Naphthyridine derivatives
US5240916A (en) * 1989-07-27 1993-08-31 Dowelanco Naphthyridine derivatives
BR112013021126A2 (pt) 2011-02-18 2019-09-24 Medivation Technologies Inc método para reduzir a pressão sanguínea, método para aumentar o fluxo sanguíneo renal ou diminuir a reabsorção de sódio, método para tratar uma doença, kit, composto e composição farmacêutica
WO2014031167A1 (en) * 2012-08-22 2014-02-27 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1474775A (en) * 1973-10-08 1977-05-25 Sandoz Ltd Isoquinolines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1006725A (fr) * 1948-08-31 1952-04-28 Cilag Spa Nouveaux dérivés de la naphtyridine et procédé pour leur préparation
GB743901A (en) * 1952-02-18 1956-01-25 Ward Blenkinsop & Co Ltd Substituted pyridines and process for the production thereof
GB745348A (en) * 1952-03-10 1956-02-22 Howards Ilford Ltd Basically substituted pyridines and process for the production thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1474775A (en) * 1973-10-08 1977-05-25 Sandoz Ltd Isoquinolines

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Chemical Abstracts, Bd. 85, 1976, 142992 d *
Chemical Abstracts, Bd. 85, 1976, 46431 z *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004352A1 (fr) * 1978-03-16 1979-10-03 Firmenich Sa Composés azotés bicycliques et leur utilisation en tant qu'ingrédients aromatisants

Also Published As

Publication number Publication date
JPS6115875B2 (US06291489-20010918-C00077.png) 1986-04-26
JPS53136000A (en) 1978-11-28
IT1107210B (it) 1985-11-25
GB1566693A (en) 1980-05-08
FR2389624B1 (US06291489-20010918-C00077.png) 1982-12-17
BE866544A (fr) 1978-10-30
DK166478A (da) 1978-11-03
FR2389624A1 (US06291489-20010918-C00077.png) 1978-12-01
IT7849081A0 (it) 1978-04-26
IE46874B1 (en) 1983-10-19
LU79551A1 (fr) 1979-02-02
CH634320A5 (en) 1983-01-31
IE780862L (en) 1978-11-02
SE7804318L (sv) 1978-11-03
NL7804168A (nl) 1978-11-06

Similar Documents

Publication Publication Date Title
EP0934311B1 (de) Neue heterocyclylmethyl-substituierte pyrazolderivate und ihre verwendung in der behandlung von herz-kreislauf-erkrankungen
DE2413935C2 (US06291489-20010918-C00077.png)
DE3324034C2 (US06291489-20010918-C00077.png)
EP0045081A2 (de) Neue trisubstituierte Imidazolderivate, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate und ihre Verwendung
EP0042100A1 (de) Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel
DE2820938A1 (de) Neue imidazoazine und imidazodiazine
EP0041215B1 (de) Imidazoazolalkensäureamide, neue Zwischenprodukte zu ihrer Herstellung, ihre Herstellung und ihre Verwendung in Arzneimitteln
EP0271795A2 (de) Octahydro-10-oxo-6H-pyridazo [1,2-a] [1,2] diazepin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel
CH632495A5 (de) Verfahren zur herstellung neuer substituierter pyridine.
EP0258729A2 (de) Dihydropyridinverbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0011142A1 (de) Pyrido (2,1-b) chinazolinon-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
DE1770595A1 (de) Substituierte Tetrahydrochinoline
CH633250A5 (de) Verfahren zur herstellung von neuen polyprenylderivaten.
DE2818290A1 (de) Neue naphthyridine
CH632499A5 (de) Verfahren zur herstellung neuer pyridin-derivate.
EP0158138B1 (de) 1-Alkylsubstituierte 1,4-Dihydropyridinlactone, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
EP0065295A1 (de) Substituierte Tryptaminderivate von Thienyloxypropanolaminen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate auf Basis dieser Verbindungen sowie ihre Verwendung
DE3514843C2 (US06291489-20010918-C00077.png)
EP0088323B1 (de) Imidazothiadiazolalkencarbonsäureamide, neue Zwischenprodukte zu ihrer Herstellung, ihre Herstellung und ihre Verwendung in Arzneimitteln
EP0242767B1 (de) N-dihydroindolylethylsulfonamide
DE2427272C3 (de) 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum
DE1908496A1 (de) Neue Thiophenderivate und Verfahren zu ihrer Herstellung
EP0180833B1 (de) 4-Oxo-pyrido[2,3]pyrimidin-Derivate, Verfahren zur deren Herstellung und diese ethaltende Arzneimittel
EP0025941A1 (de) Pyridazopyridazinderivate, Verfahren zu deren Herstellung und Arzneimittel enthaltend solche Pyridazopyridazinderivate
DE3020421A1 (de) Imidazoazolalkensaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection