DE2804723A1 - 9-(2,6-dihalogenbenzyl)-adenine und verfahren zu ihrer herstellung und reinigung - Google Patents

9-(2,6-dihalogenbenzyl)-adenine und verfahren zu ihrer herstellung und reinigung

Info

Publication number
DE2804723A1
DE2804723A1 DE19782804723 DE2804723A DE2804723A1 DE 2804723 A1 DE2804723 A1 DE 2804723A1 DE 19782804723 DE19782804723 DE 19782804723 DE 2804723 A DE2804723 A DE 2804723A DE 2804723 A1 DE2804723 A1 DE 2804723A1
Authority
DE
Germany
Prior art keywords
adenine
chloro
fluorobenzyl
liquid
isomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19782804723
Other languages
German (de)
English (en)
Other versions
DE2804723C2 (fi
Inventor
George David Hartman
Ichiro Shinkai
Roger James Tull
Leonard Maurice Weinstock
Michael Cornelis Vander Zwan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/766,326 external-priority patent/US4100159A/en
Priority claimed from US05/768,235 external-priority patent/US4098787A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2804723A1 publication Critical patent/DE2804723A1/de
Application granted granted Critical
Publication of DE2804723C2 publication Critical patent/DE2804723C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19782804723 1977-02-07 1978-02-03 9-(2,6-dihalogenbenzyl)-adenine und verfahren zu ihrer herstellung und reinigung Granted DE2804723A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/766,326 US4100159A (en) 1977-02-07 1977-02-07 Process for preparation of 9-(2,6-dihalobenzyl)adenines
US05/768,235 US4098787A (en) 1977-02-14 1977-02-14 Process for preparation of 9-(dihalobenzyl) adenines
US84391977A 1977-10-20 1977-10-20

Publications (2)

Publication Number Publication Date
DE2804723A1 true DE2804723A1 (de) 1978-08-10
DE2804723C2 DE2804723C2 (fi) 1990-11-29

Family

ID=27419624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782804723 Granted DE2804723A1 (de) 1977-02-07 1978-02-03 9-(2,6-dihalogenbenzyl)-adenine und verfahren zu ihrer herstellung und reinigung

Country Status (23)

Country Link
JP (1) JPS53124294A (fi)
AR (1) AR225000A1 (fi)
AT (1) AT361008B (fi)
CH (1) CH636614A5 (fi)
DD (1) DD136744A5 (fi)
DE (1) DE2804723A1 (fi)
DK (1) DK36078A (fi)
EG (1) EG13333A (fi)
ES (1) ES466647A1 (fi)
FI (1) FI64596C (fi)
FR (1) FR2379536A1 (fi)
GB (1) GB1586537A (fi)
GR (1) GR64457B (fi)
IE (1) IE46399B1 (fi)
IL (1) IL53922A (fi)
IT (1) IT1105174B (fi)
NL (1) NL7800896A (fi)
NO (1) NO148374C (fi)
NZ (1) NZ186357A (fi)
PL (1) PL118655B1 (fi)
PT (1) PT67606B (fi)
SE (1) SE440355B (fi)
YU (1) YU27778A (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089618A (en) * 1989-08-01 1992-02-18 Lonza Ltd. Process for the purification of adenine

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900826A (en) * 1981-09-24 1990-02-13 Kohjin Co., Ltd. Process for preparing N6,9-disubstituted adenine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846426A (en) * 1971-03-03 1974-11-05 Int Minerals & Chem Corp 6-amino-9-(substituted benzyl) purines and their n{11 oxides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846426A (en) * 1971-03-03 1974-11-05 Int Minerals & Chem Corp 6-amino-9-(substituted benzyl) purines and their n{11 oxides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089618A (en) * 1989-08-01 1992-02-18 Lonza Ltd. Process for the purification of adenine

Also Published As

Publication number Publication date
PT67606B (en) 1980-03-03
FR2379536A1 (fr) 1978-09-01
IL53922A0 (en) 1978-04-30
GB1586537A (en) 1981-03-18
IE46399B1 (en) 1983-06-01
IT7847941A0 (it) 1978-02-06
ATA79778A (de) 1980-07-15
DK36078A (da) 1978-08-08
FI64596B (fi) 1983-08-31
DD136744A5 (de) 1979-07-25
PL118655B1 (en) 1981-10-31
FI64596C (fi) 1983-12-12
GR64457B (en) 1980-03-24
IE780253L (en) 1978-08-07
NO148374B (no) 1983-06-20
YU27778A (en) 1983-12-31
PL204447A1 (pl) 1979-06-04
FI780200A (fi) 1978-08-08
AR225000A1 (es) 1982-02-15
EG13333A (en) 1981-06-30
SE7800977L (sv) 1978-08-08
SE440355B (sv) 1985-07-29
NO780284L (no) 1978-08-08
ES466647A1 (es) 1980-12-16
PT67606A (en) 1978-03-01
IL53922A (en) 1981-02-27
JPS53124294A (en) 1978-10-30
CH636614A5 (en) 1983-06-15
FR2379536B1 (fi) 1983-10-07
DE2804723C2 (fi) 1990-11-29
IT1105174B (it) 1985-10-28
AT361008B (de) 1981-02-10
NL7800896A (nl) 1978-08-09
NO148374C (no) 1983-09-28
NZ186357A (en) 1981-03-16

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee