DE2653838A1 - Polyenverbindungen - Google Patents

Polyenverbindungen

Info

Publication number
DE2653838A1
DE2653838A1 DE19762653838 DE2653838A DE2653838A1 DE 2653838 A1 DE2653838 A1 DE 2653838A1 DE 19762653838 DE19762653838 DE 19762653838 DE 2653838 A DE2653838 A DE 2653838A DE 2653838 A1 DE2653838 A1 DE 2653838A1
Authority
DE
Germany
Prior art keywords
formula
trimethyl
methyl
oxo
penta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19762653838
Other languages
German (de)
English (en)
Other versions
DE2653838C2 (US20050065096A1-20050324-C00069.png
Inventor
Frank Dr Kienzle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE2653838A1 publication Critical patent/DE2653838A1/de
Application granted granted Critical
Publication of DE2653838C2 publication Critical patent/DE2653838C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40—Colouring or decolouring of foods
    • A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/47—Addition of dyes or pigments, e.g. in combination with optical brighteners using synthetic organic dyes or pigments not covered by groups A23L5/43 - A23L5/46
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5428—Acyclic unsaturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19762653838 1975-11-30 1976-11-26 Polyenverbindungen Granted DE2653838A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1546575A CH623304A5 (US20050065096A1-20050324-C00069.png) 1975-11-30 1975-11-30

Publications (2)

Publication Number Publication Date
DE2653838A1 true DE2653838A1 (de) 1977-06-02
DE2653838C2 DE2653838C2 (US20050065096A1-20050324-C00069.png) 1989-12-21

Family

ID=4409336

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19762653838 Granted DE2653838A1 (de) 1975-11-30 1976-11-26 Polyenverbindungen

Country Status (10)

Country Link
US (1) US4156090A (US20050065096A1-20050324-C00069.png)
JP (1) JPS6023136B2 (US20050065096A1-20050324-C00069.png)
AT (1) AT344680B (US20050065096A1-20050324-C00069.png)
BE (1) BE848851A (US20050065096A1-20050324-C00069.png)
CH (1) CH623304A5 (US20050065096A1-20050324-C00069.png)
DE (1) DE2653838A1 (US20050065096A1-20050324-C00069.png)
FR (1) FR2357541A1 (US20050065096A1-20050324-C00069.png)
GB (1) GB1561390A (US20050065096A1-20050324-C00069.png)
IT (1) IT1123935B (US20050065096A1-20050324-C00069.png)
NL (1) NL7612971A (US20050065096A1-20050324-C00069.png)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0077439A2 (de) * 1981-10-16 1983-04-27 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cyclohexenderivaten, sowie ein neues Ausgangsprodukt und neue Zwischenprodukte in diesem Verfahren
US4405417A (en) 1982-02-09 1983-09-20 Hoffmann- La Roche Inc. Process for the manufacture of cyclohexene derivatives
EP0101597A2 (de) * 1982-08-20 1984-02-29 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Astaxanthin und Zwischenprodukten in der Astaxanthin-Synthese
EP0455119A2 (de) * 1990-05-03 1991-11-06 BASF Aktiengesellschaft Verfahren zur Herstellung von Canthaxanthin und Astaxanthin
EP0733619A1 (de) * 1995-03-18 1996-09-25 BASF Aktiengesellschaft Verfahren zur Herstellung von Astaxanthin
WO2018050793A1 (en) 2016-09-16 2018-03-22 Basf Se Process for preparing phosphonium salt esters as building blocks for carotenoides

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153615A (en) * 1978-03-27 1979-05-08 Hoffmann-La Roche Inc. Method of producing coloring agents
EP0005748B1 (de) * 1978-06-02 1982-12-29 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cyclohexenderivaten sowie Zwischenprodukte in diesem Verfahren
DE2965093D1 (en) * 1978-06-02 1983-05-05 Hoffmann La Roche Derivatives of cyclohexene, process for their peparation, as well as their uses
DE3264786D1 (en) * 1981-11-04 1985-08-22 Basf Ag Acetylene derivatives, process for their preparation and their use in the regulation of the growth of plants
EP0120341B1 (de) * 1983-03-25 1989-01-25 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Pentadienol-Derivaten
US5225604A (en) * 1989-11-27 1993-07-06 Neurosearch A/S Hydroxycarbonyl derivatives and process for making the same
DK595489D0 (da) * 1989-11-27 1989-11-27 Neurosearch As Hydroxycarbonylderivater og fremgangsmaade til fremstilling af samme
KR100388110B1 (ko) * 2000-05-04 2003-06-18 해태제과식품주식회사 효모 균주에서 아스타산틴 색소 추출방법 및 추출된 색소
KR100411364B1 (ko) * 2000-08-04 2003-12-18 해태제과식품주식회사 녹조류에서 아스타산틴 색소 추출방법 및 추출된 색소
US7375133B2 (en) 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US7320997B2 (en) * 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
US7763649B2 (en) * 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
US7723327B2 (en) * 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
US20050009788A1 (en) * 2002-07-29 2005-01-13 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling connexin 43 expression
WO2004011423A2 (en) * 2002-07-29 2004-02-05 Hawaii Biotech, Inc. Structural carotenoid analogs for the inhibition and amelioration of disease
US7521584B2 (en) * 2002-07-29 2009-04-21 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of disease
US20050059659A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid analogs or derivatives for controlling C-reactive protein levels
US7345091B2 (en) * 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
US20050049248A1 (en) * 2002-07-29 2005-03-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for controlling C-reactive protein levels
US20050004235A1 (en) * 2002-07-29 2005-01-06 Lockwood Samuel Fournier Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease
US20050026874A1 (en) * 2002-07-29 2005-02-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease
US20090099061A1 (en) * 2006-01-27 2009-04-16 Foss Bente J Synthesis of carotenoid analogs or derivatives with improved antioxidant characteristics
WO2008118862A1 (en) * 2007-03-23 2008-10-02 Cardax Pharmaceuticals, Inc. Carotenoid analogs and derivatives for the prevention of platelet aggregation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1105869B (de) * 1958-10-24 1961-05-04 Hoffmann La Roche Verfahren zur Herstellung von alicyclischen Carotinoidverbindungen
US3000982A (en) * 1958-10-24 1961-09-19 Hoffmann La Roche Preparation of carotenoid compounds
GB1250869A (US20050065096A1-20050324-C00069.png) * 1969-08-01 1971-10-20

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1288386A (fr) * 1961-04-13 1962-03-24 Roche Products Ltd Procédé pour la préparation de caroténoïdes
US3299111A (en) * 1963-01-02 1967-01-17 Diamond Alkali Co Unsaturated acids derived from polyacetylenic compounds
US3917675A (en) * 1973-03-15 1975-11-04 Givaudan Corp Novel odorants
US4000198A (en) * 1975-06-09 1976-12-28 Hoffmann-La Roche Inc. Hydroxy-acetylene-substituted cyclohexenone

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1105869B (de) * 1958-10-24 1961-05-04 Hoffmann La Roche Verfahren zur Herstellung von alicyclischen Carotinoidverbindungen
US3000982A (en) * 1958-10-24 1961-09-19 Hoffmann La Roche Preparation of carotenoid compounds
GB1250869A (US20050065096A1-20050324-C00069.png) * 1969-08-01 1971-10-20

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Angew.Chem., 72, 1960, S. 641 *
FIESER: Org. Chemie, Verlag Chemie, 1965, S. 1585 *
Helv.Chim. Acta, 53, 1970, S. 974-990 *
J.Chem.Soc. Perkin Trans. I, 1975, S. 2195-2204 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0077439A2 (de) * 1981-10-16 1983-04-27 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cyclohexenderivaten, sowie ein neues Ausgangsprodukt und neue Zwischenprodukte in diesem Verfahren
EP0077439A3 (en) * 1981-10-16 1984-02-01 F. Hoffmann-La Roche & Co. Aktiengesellschaft Process for the preparation of cyclohexene derivatives, and a starting product and intermediary products in this process
US4405417A (en) 1982-02-09 1983-09-20 Hoffmann- La Roche Inc. Process for the manufacture of cyclohexene derivatives
EP0101597A2 (de) * 1982-08-20 1984-02-29 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Astaxanthin und Zwischenprodukten in der Astaxanthin-Synthese
EP0101597A3 (en) * 1982-08-20 1985-11-27 F. Hoffmann-La Roche & Co. Aktiengesellschaft Process for the preparation of astaxanthine and intermediates in the astaxanthine synthesis
EP0455119A2 (de) * 1990-05-03 1991-11-06 BASF Aktiengesellschaft Verfahren zur Herstellung von Canthaxanthin und Astaxanthin
EP0455119A3 (en) * 1990-05-03 1992-04-15 Basf Aktiengesellschaft Process for the preparation of canthaxanthin and astaxanthin
EP0733619A1 (de) * 1995-03-18 1996-09-25 BASF Aktiengesellschaft Verfahren zur Herstellung von Astaxanthin
US5654488A (en) * 1995-03-18 1997-08-05 Basf Aktiengesellschaft Preparation of astaxanthin
WO2018050793A1 (en) 2016-09-16 2018-03-22 Basf Se Process for preparing phosphonium salt esters as building blocks for carotenoides

Also Published As

Publication number Publication date
NL7612971A (nl) 1977-06-01
JPS5268157A (en) 1977-06-06
ATA882376A (de) 1977-12-15
GB1561390A (en) 1980-02-20
FR2357541B1 (US20050065096A1-20050324-C00069.png) 1980-11-07
CH623304A5 (US20050065096A1-20050324-C00069.png) 1981-05-29
BE848851A (fr) 1977-05-31
AT344680B (de) 1978-08-10
FR2357541A1 (fr) 1978-02-03
DE2653838C2 (US20050065096A1-20050324-C00069.png) 1989-12-21
US4156090A (en) 1979-05-22
JPS6023136B2 (ja) 1985-06-06
IT1123935B (it) 1986-04-30

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8327 Change in the person/name/address of the patent owner

Owner name: F. HOFFMANN-LA ROCHE AG, BASEL, CH

8328 Change in the person/name/address of the agent

Free format text: LEDERER, F., DIPL.-CHEM. DR., 8000 MUENCHEN RIEDERER FRHR. VON PAAR ZU SCHOENAU, A., DIPL.-ING., PAT.-ANWAELTE, 8300 LANDSHUT

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee