DE2637670A1 - Verfahren zur herstellung von 4-hydroxymethylimidazol-derivaten - Google Patents

Verfahren zur herstellung von 4-hydroxymethylimidazol-derivaten

Info

Publication number
DE2637670A1
DE2637670A1 DE19762637670 DE2637670A DE2637670A1 DE 2637670 A1 DE2637670 A1 DE 2637670A1 DE 19762637670 DE19762637670 DE 19762637670 DE 2637670 A DE2637670 A DE 2637670A DE 2637670 A1 DE2637670 A1 DE 2637670A1
Authority
DE
Germany
Prior art keywords
added
methyl
ammonia
hydroxymethylimidazole
alkali metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19762637670
Other languages
German (de)
English (en)
Other versions
DE2637670C2 (de
Inventor
Elvin Lowell Anderson
Wilford Lee Mendelson
George Robert Wellman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/690,476 external-priority patent/US4063023A/en
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of DE2637670A1 publication Critical patent/DE2637670A1/de
Application granted granted Critical
Publication of DE2637670C2 publication Critical patent/DE2637670C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
DE2637670A 1975-08-20 1976-08-20 Verfahren zur Herstellung von 4-Hydroxymethylimidazolen Expired DE2637670C2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60627075A 1975-08-20 1975-08-20
US05/690,476 US4063023A (en) 1975-08-20 1976-05-27 Process for preparing 4-(hydroxymethyl)imidazole compounds

Publications (2)

Publication Number Publication Date
DE2637670A1 true DE2637670A1 (de) 1977-03-03
DE2637670C2 DE2637670C2 (de) 1987-02-26

Family

ID=27085194

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2637670A Expired DE2637670C2 (de) 1975-08-20 1976-08-20 Verfahren zur Herstellung von 4-Hydroxymethylimidazolen

Country Status (28)

Country Link
JP (1) JPS6025428B2 (fi)
AT (1) AT358574B (fi)
AU (1) AU496917B2 (fi)
CA (1) CA1064940A (fi)
DD (1) DD126871A5 (fi)
DE (1) DE2637670C2 (fi)
DK (1) DK143749C (fi)
EG (1) EG12426A (fi)
ES (1) ES450371A1 (fi)
FI (1) FI64356C (fi)
FR (1) FR2321490A1 (fi)
GB (1) GB1562811A (fi)
GR (1) GR61130B (fi)
HU (1) HU177508B (fi)
IE (1) IE44020B1 (fi)
IL (1) IL50147A (fi)
IN (1) IN147803B (fi)
LU (1) LU75612A1 (fi)
MX (1) MX3532E (fi)
NL (1) NL183581C (fi)
NO (1) NO145072C (fi)
NZ (1) NZ181647A (fi)
OA (1) OA05422A (fi)
PH (1) PH13166A (fi)
PT (1) PT65369B (fi)
RO (1) RO72826A (fi)
SE (1) SE415097B (fi)
YU (1) YU39616B (fi)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003052A2 (de) 1978-01-03 1979-07-25 BASF Aktiengesellschaft Verfahren zur Herstellung von 4-Methyl-5-chlormethylimidazol
EP0006102A1 (de) * 1978-06-10 1980-01-09 BASF Aktiengesellschaft 1-Hydroxymethylimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als chemische Zwischenprodukte

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ184893A (en) * 1976-09-21 1980-11-28 Smith Kline French Lab Pure crystalline form of cimetidine a(n-methyl-n-cyano-n-(-2-(5-methyl-4imidazolyl) methylthio) ethyl)-guanidine andpharmaceutical compositions containing it
JPS5914460B2 (ja) * 1978-12-27 1984-04-04 相互薬工株式会社 Ｈ↓２受容体「きつ」抗剤シメチジンの製造法
JPS63117318U (fi) * 1987-01-24 1988-07-29
JPH0619559U (ja) * 1992-03-16 1994-03-15 加藤 利夫 歯ブラシ

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003052A2 (de) 1978-01-03 1979-07-25 BASF Aktiengesellschaft Verfahren zur Herstellung von 4-Methyl-5-chlormethylimidazol
EP0006102A1 (de) * 1978-06-10 1980-01-09 BASF Aktiengesellschaft 1-Hydroxymethylimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als chemische Zwischenprodukte

Also Published As

Publication number Publication date
SE7608831L (sv) 1977-02-21
DK143749C (da) 1982-03-22
NO762866L (fi) 1977-02-22
IE44020L (en) 1977-02-20
FI64356B (fi) 1983-07-29
ATA606376A (de) 1980-02-15
YU39616B (en) 1985-03-20
IE44020B1 (en) 1981-07-29
FI64356C (fi) 1983-11-10
DK143749B (da) 1981-10-05
IL50147A (en) 1980-11-30
GR61130B (en) 1978-09-15
DE2637670C2 (de) 1987-02-26
NO145072C (no) 1982-01-06
NL183581B (nl) 1988-07-01
RO72826A (ro) 1982-09-09
AU496917B2 (en) 1978-11-09
GB1562811A (en) 1980-03-19
FR2321490B1 (fi) 1978-05-05
JPS6025428B2 (ja) 1985-06-18
IN147803B (fi) 1980-07-05
OA05422A (fr) 1981-03-31
HU177508B (en) 1981-10-28
PT65369B (en) 1978-01-10
IL50147A0 (en) 1976-09-30
NZ181647A (en) 1978-06-02
FR2321490A1 (fr) 1977-03-18
LU75612A1 (fi) 1977-03-29
FI762306A (fi) 1977-02-21
JPS5225770A (en) 1977-02-25
CA1064940A (en) 1979-10-23
NO145072B (no) 1981-09-28
NL7609296A (nl) 1977-02-22
NL183581C (nl) 1988-12-01
PT65369A (en) 1976-08-01
MX3532E (es) 1981-02-03
SE415097B (sv) 1980-09-08
PH13166A (en) 1980-01-08
DD126871A5 (fi) 1977-08-17
DK331976A (da) 1977-02-21
EG12426A (en) 1979-03-31
AU1703976A (en) 1978-02-23
ES450371A1 (es) 1977-12-01
YU191376A (en) 1982-08-31
AT358574B (de) 1980-09-25

Similar Documents

Publication Publication Date Title
DE1958919B2 (de) l-Oxo-5-indanyloxyessigsäuren und solche Verbindungen enthaltende Arzneimittel
DE2528069C3 (de) Verfahren zur Herstellung von Aminocarbonsäureestern
DE2637670C2 (de) Verfahren zur Herstellung von 4-Hydroxymethylimidazolen
DE2446254C2 (de) 5-Substituierte Niedrigalkyl-1,3,4-thiadiazol-2-thiol-Verbindungen und Verfahren zu ihrer Herstellung
DE2521709C3 (de) Verfahren zur Herstellung von in 2- und 6- Stellung substituierten 1- Benzoyl-2-phenyl-amino-2-imidazolinderivaten
DE2841644C2 (fi)
EP0782991B1 (de) Verfahren zur Herstellung von 2-substituierten 5-Chlorimidazol-4-carbaldehyden
DD249479A5 (de) Verfahren zur herstellung von propionamidin-derivaten
EP0083729B1 (de) Substituierte 1-Benzoyl-2-phenylimino-imidazolidine, deren Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2805221A1 (de) Imidazolylmethyltriphenylphosphoniumsalze, verfahren zu ihrer herstellung und ihre weiterverarbeitung
CH605807A5 (en) 4:Hydroxymethyl imidazoles prodn.
EP0552758A1 (de) N-5-geschützte 2,5-Diamino-4,6-dichlorpyrimidine und Verfahren zu deren Herstellung
DE1595884C3 (de) Verfahren zur Herstellung von 2-Nitrolmidazolen
US4063023A (en) Process for preparing 4-(hydroxymethyl)imidazole compounds
EP0015516B1 (de) Verfahren zur Herstellung von 5-Hydroxymethylimidazolen
DE2814355C3 (de) Verfahren zur Herstellung von 4-Methyl-5-[(2-aminoäthyl)-thiomethyl]-imidazol-dihydrochlorid
DE2649059A1 (de) Verfahren zur herstellung von imidazolen
DE2943809A1 (de) 1-mercaptoacylpiperazin-2-carbonsaeure-verbindungen und ihre salze, verfahren zu ihrer herstellung und ihre verwendung bei der bekaempfung von hypertonie
EP0003052A2 (de) Verfahren zur Herstellung von 4-Methyl-5-chlormethylimidazol
DE2111610C3 (de) Verfahren zur Herstellung von Salzen von Pyrimidyl-pyridiniumderivaten
DE2065698B2 (de) Verfahren zur Herstellung von 2-Isopropyl-6-methyl-4(3H)-pyrimidon
US4383115A (en) Imino-alkyl and amino-nitrile cyano-guanidines
DE2164618A1 (de) Verbindung mit antihypertensiver Wir kung und Verfahren zu ihrer Herstellung
DE2650781A1 (de) 1,2,3,4-tetrahydro-2,3-naphthalindiole und diese verbindungen enthaltende arzneimittel
AT373588B (de) Verfahren zur herstellung von neuen substituierten 1-benzoyl-2-phenylimino-imidazolidinen und von deren salzen

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8127 New person/name/address of the applicant

Owner name: SMITHKLINE BECKMAN CORP., 19101 PHILADELPHIA, PA.,

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee