DE2627212A1 - Cephalosporinantibiotika - Google Patents

Cephalosporinantibiotika

Info

Publication number
DE2627212A1
DE2627212A1 DE19762627212 DE2627212A DE2627212A1 DE 2627212 A1 DE2627212 A1 DE 2627212A1 DE 19762627212 DE19762627212 DE 19762627212 DE 2627212 A DE2627212 A DE 2627212A DE 2627212 A1 DE2627212 A1 DE 2627212A1
Authority
DE
Germany
Prior art keywords
alkyl
compound
formula
acid
syn isomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19762627212
Other languages
German (de)
English (en)
Inventor
Michael Walter Foxton
Gordon Ian Gregory
David Malcolm Rogers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of DE2627212A1 publication Critical patent/DE2627212A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19762627212 1975-06-19 1976-06-18 Cephalosporinantibiotika Withdrawn DE2627212A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB26188/75A GB1555471A (en) 1975-06-19 1975-06-19 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof

Publications (1)

Publication Number Publication Date
DE2627212A1 true DE2627212A1 (de) 1977-01-13

Family

ID=10239713

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19762627212 Withdrawn DE2627212A1 (de) 1975-06-19 1976-06-18 Cephalosporinantibiotika

Country Status (14)

Country Link
US (1) US4074047A (https=)
JP (1) JPS5214793A (https=)
AT (1) AT353956B (https=)
AU (1) AU505041B2 (https=)
BE (1) BE843152A (https=)
CH (1) CH625526A5 (https=)
DE (1) DE2627212A1 (https=)
DK (1) DK272676A (https=)
ES (1) ES449032A1 (https=)
FR (1) FR2315933A1 (https=)
GB (1) GB1555471A (https=)
NL (1) NL7606614A (https=)
SE (1) SE7607037L (https=)
ZA (1) ZA763635B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5517823B2 (https=) * 1972-05-16 1980-05-14
JPS4986668A (https=) * 1972-12-27 1974-08-20
US4175185A (en) * 1976-05-19 1979-11-20 Meiji Seika Kaisha Ltd. Process for preparing cephalosporanic acid derivatives
GB1591439A (en) * 1976-10-01 1981-06-24 Glaxo Operations Ltd 7-syn (oxyimino -acylamido) cephalosporins
US4208517A (en) * 1976-11-30 1980-06-17 Glaxo Operations Uk Limited Caphalosporin compounds having at position-7 an α-etherified hydroxyiminoarylacetamido group
GB1596278A (en) * 1976-11-30 1981-08-26 Glaxo Operations Ltd 7-(-oxyimino-acetamino)cephalosporin derivatives
NL7805715A (nl) * 1977-06-03 1978-12-05 Hoffmann La Roche Werkwijze voor het bereiden van acylderivaten.
EP0059486B1 (en) * 1978-07-17 1985-10-02 Fujisawa Pharmaceutical Co., Ltd. New starting compounds for preparing cephem compounds and processes for their preparation
NO782998L (no) * 1978-07-19 1980-01-22 Hoffmann La Roche Cephalosporinestere og -etere.
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
US4198504A (en) * 1978-11-02 1980-04-15 Bristol-Myers Company [3-(Pyridinium)-7-(naphthyiridinyl carbonylamino)acetamido]cephalosporanic acid derivatives
US4337376A (en) * 1979-12-31 1982-06-29 Broadcom, Incorporated Communications system and network
US7427680B2 (en) * 2001-01-12 2008-09-23 The Regents Of The University Of California Fluorogenic substrates for BETA-lactamase gene expression
WO2005071096A2 (en) * 2004-01-21 2005-08-04 Molecular Probes, Inc. Derivatives of cephalosporin and clavulanic acid for detecting beta-lacamase in a sample
CN114478149B (zh) * 2022-01-18 2023-09-15 吉林化工学院 一种羧酸类化合物及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2223375A1 (de) * 1971-05-14 1972-11-23 Glaxo Lab Ltd Antibiotika und Verfahren zu ihrer Herstellung
DE2439880A1 (de) * 1973-08-21 1975-04-03 Glaxo Lab Ltd Antibiotika und verfahren zu ihrer herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1389194A (en) * 1971-01-29 1975-04-03 Glaxo Lab Ltd Antibiotics
US3971778A (en) * 1972-05-12 1976-07-27 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
DE2262500A1 (de) * 1972-12-20 1973-07-05 Lilly Co Eli 3-oxyiminomethylcephalosporinverbindungen
IL46302A (en) * 1973-12-21 1978-09-29 Glaxo Lab Ltd 7 -( -(etherified oxyimino)-acylamido)cephalosporanic acid derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2223375A1 (de) * 1971-05-14 1972-11-23 Glaxo Lab Ltd Antibiotika und Verfahren zu ihrer Herstellung
DE2439880A1 (de) * 1973-08-21 1975-04-03 Glaxo Lab Ltd Antibiotika und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ZA763635B (en) 1977-05-25
GB1555471A (en) 1979-11-14
FR2315933A1 (fr) 1977-01-28
DK272676A (da) 1976-12-20
AU505041B2 (en) 1979-11-08
ES449032A1 (es) 1977-11-16
AT353956B (de) 1979-12-10
BE843152A (fr) 1976-12-20
US4074047A (en) 1978-02-14
CH625526A5 (https=) 1981-09-30
JPS5214793A (en) 1977-02-03
NL7606614A (nl) 1976-12-21
AU1503276A (en) 1977-12-22
ATA445876A (de) 1979-05-15
FR2315933B1 (https=) 1979-10-12
SE7607037L (sv) 1976-12-20

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: ZUMSTEIN SEN., F., DR. ASSMANN, E., DIPL.-CHEM. DR

8139 Disposal/non-payment of the annual fee