DE2608192B2 - Automatische Analysenanlage für eine Blutprobe - Google Patents
Automatische Analysenanlage für eine BlutprobeInfo
- Publication number
- DE2608192B2 DE2608192B2 DE2608192A DE2608192A DE2608192B2 DE 2608192 B2 DE2608192 B2 DE 2608192B2 DE 2608192 A DE2608192 A DE 2608192A DE 2608192 A DE2608192 A DE 2608192A DE 2608192 B2 DE2608192 B2 DE 2608192B2
- Authority
- DE
- Germany
- Prior art keywords
- hemoglobin
- hematocrit
- blood
- flow path
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 210000004369 blood Anatomy 0.000 title claims description 42
- 239000008280 blood Substances 0.000 title claims description 42
- 238000004458 analytical method Methods 0.000 title claims description 12
- 108010054147 Hemoglobins Proteins 0.000 claims description 40
- 102000001554 Hemoglobins Human genes 0.000 claims description 40
- 210000003743 erythrocyte Anatomy 0.000 claims description 39
- 239000000523 sample Substances 0.000 claims description 38
- 210000000265 leukocyte Anatomy 0.000 claims description 37
- 239000003153 chemical reaction reagent Substances 0.000 claims description 23
- 239000000243 solution Substances 0.000 claims description 22
- 238000005534 hematocrit Methods 0.000 claims description 17
- 230000002949 hemolytic effect Effects 0.000 claims description 17
- 238000003756 stirring Methods 0.000 claims description 15
- 239000012895 dilution Substances 0.000 claims description 12
- 238000010790 dilution Methods 0.000 claims description 12
- 239000003085 diluting agent Substances 0.000 claims description 11
- 238000007865 diluting Methods 0.000 claims description 6
- 238000004737 colorimetric analysis Methods 0.000 claims description 5
- 239000012470 diluted sample Substances 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 2
- 210000000601 blood cell Anatomy 0.000 description 13
- 238000004820 blood count Methods 0.000 description 8
- 238000010586 diagram Methods 0.000 description 8
- 238000005259 measurement Methods 0.000 description 8
- 239000007788 liquid Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 3
- 229910052753 mercury Inorganic materials 0.000 description 3
- 108010064719 Oxyhemoglobins Proteins 0.000 description 2
- 230000005856 abnormality Effects 0.000 description 2
- 238000004159 blood analysis Methods 0.000 description 2
- 238000009534 blood test Methods 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 238000000265 homogenisation Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 206010018910 Haemolysis Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1486—Counting the particles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
Landscapes
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50024531A JPS5916667B2 (ja) | 1975-02-28 | 1975-02-28 | 自動血液分析装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2608192A1 DE2608192A1 (de) | 1976-09-09 |
| DE2608192B2 true DE2608192B2 (de) | 1978-11-09 |
Family
ID=12140726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2608192A Ceased DE2608192B2 (de) | 1975-02-28 | 1976-02-27 | Automatische Analysenanlage für eine Blutprobe |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4030888A (enExample) |
| JP (1) | JPS5916667B2 (enExample) |
| BR (2) | BR7601293A (enExample) |
| DE (1) | DE2608192B2 (enExample) |
| FR (1) | FR2302525A1 (enExample) |
| GB (1) | GB1503246A (enExample) |
| IT (1) | IT1070234B (enExample) |
| NL (1) | NL7601910A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0187644A3 (en) * | 1985-01-06 | 1987-12-02 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem | A method and apparatus for the localization of bleeding in the gastrointestinal tract |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4127111A (en) * | 1976-10-26 | 1978-11-28 | Drolet Roland A | Automatic blood sampling system and method |
| US4185964A (en) * | 1977-02-08 | 1980-01-29 | Central Laboratories of Associated Maryland Pathologists, Ltd. | Lysing reagent |
| US4134678A (en) * | 1977-03-16 | 1979-01-16 | Instrumentation Laboratory Inc. | Automatic blood analysis apparatus and method |
| GB1603643A (en) * | 1978-03-06 | 1981-11-25 | Coulter Electronics | Detection of blood disorders |
| US4157499A (en) * | 1977-09-15 | 1979-06-05 | Becton, Dickinson And Company | Blood cell counter having dual testing heads |
| US4167038A (en) * | 1977-10-17 | 1979-09-04 | Hycel, Inc. | Calculated parameter generation in a hematology parameter measurement apparatus |
| JPS54107396A (en) * | 1978-02-09 | 1979-08-23 | Toa Medical Electronics | Blood checking device |
| CH610666A5 (enExample) * | 1978-03-14 | 1979-04-30 | Contraves Ag | |
| US4737342A (en) * | 1982-08-06 | 1988-04-12 | Ciba Corning Diagnostics Corp. | Test module |
| JPS60162955A (ja) * | 1984-02-03 | 1985-08-24 | Hitachi Ltd | 血球自動分析装置 |
| US4726237A (en) * | 1985-06-19 | 1988-02-23 | Sequoia-Turner Corporation | Fluid metering apparatus and method |
| US4706207A (en) * | 1985-06-24 | 1987-11-10 | Nova Celltrak, Inc. | Count accuracy control means for a blood analyses system |
| US4859605A (en) * | 1986-12-16 | 1989-08-22 | Ciba-Geigy Corporation | Process for preparation of samples for analysis |
| DE3781677T2 (de) * | 1986-10-17 | 1993-04-01 | Baxter Int | Verfahren und vorrichtung zur bestimmung von haematokrit in einem system zur bearbeitung von blutbestandteilen. |
| US4894345A (en) * | 1986-12-16 | 1990-01-16 | Ciba-Geigy Corporation | Process for preparation of samples for analysis |
| US4900683A (en) * | 1986-12-16 | 1990-02-13 | Ciba-Geigy Corporation | Process for preparation of samples for analysis |
| WO1992001934A1 (en) * | 1990-07-17 | 1992-02-06 | Pasula Mark J | Blood testing apparatus |
| JP2573091B2 (ja) * | 1990-09-23 | 1997-01-16 | 株式会社堀場製作所 | 液体測定装置 |
| JP2972367B2 (ja) * | 1991-03-20 | 1999-11-08 | 株式会社日立製作所 | 細胞分析装置 |
| JP3077772B2 (ja) * | 1991-06-05 | 2000-08-14 | シスメックス株式会社 | 複数の分析モジュールを用いる粒子自動分析方法及び装置 |
| US5380491A (en) * | 1993-01-21 | 1995-01-10 | Cdc Technologies, Inc. | Apparatus for pumping and directing fluids for hematology testing |
| US6812032B1 (en) | 1993-01-21 | 2004-11-02 | Cdc Technologies, Inc. | Apparatus and method for making a plurality of reagent mixtures and analyzing particle distributions of the reagent mixtures |
| US5728351A (en) * | 1993-01-21 | 1998-03-17 | Cdc Technologies, Inc. | Apparatus for making a plurality of reagent mixtures and analyzing particle distributions of the reagent mixtures |
| US5503036A (en) * | 1994-05-09 | 1996-04-02 | Ciba Corning Diagnostics Corp. | Obstruction detection circuit for sample probe |
| US5840254A (en) * | 1995-06-02 | 1998-11-24 | Cdc Technologies, Inc. | Apparatus for mixing fluids for analysis |
| US5915282A (en) * | 1995-12-14 | 1999-06-22 | Abbott Laboratories | Fluid handler and method of handling a fluid |
| US5965828A (en) * | 1995-12-14 | 1999-10-12 | Abbott Laboratories | Fluid handler and method of handling a fluid |
| US5723795A (en) * | 1995-12-14 | 1998-03-03 | Abbott Laboratories | Fluid handler and method of handling a fluid |
| DE69819996T2 (de) * | 1997-09-27 | 2004-09-02 | Horiba Ltd. | Gerät für die Zählung von Blutzellen und zur immunologischen Bestimmung unter Verwendung von Vollblut |
| US6632844B1 (en) | 2000-03-29 | 2003-10-14 | Washington University | Methods and compositions for preserving glucose level in blood specimens |
| US7113817B1 (en) * | 2001-10-04 | 2006-09-26 | Wintec, Llc | Optical imaging of blood circulation velocities |
| WO2006019242A1 (en) * | 2004-08-17 | 2006-02-23 | Korea Advanced Institute Of Science And Technology | Device and method for measuring fine particle concentration |
| US20060188995A1 (en) * | 2005-02-24 | 2006-08-24 | Ryan Wayne L | Process, composition and kit for providing a stable whole blood calibrator/control |
| US9243993B2 (en) * | 2005-03-17 | 2016-01-26 | Sysmex Corporation | Sample analyzer and sample analyzing method |
| US7361510B2 (en) * | 2006-01-20 | 2008-04-22 | Beckman Coulter, Inc. | Methods of detection of iron deficiency |
| JP5162177B2 (ja) * | 2007-07-31 | 2013-03-13 | シスメックス株式会社 | 粒子分析装置及び粒子分析方法 |
| JP6116490B2 (ja) | 2011-03-09 | 2017-04-19 | ピクセル メディカル テクノロジーズ リミテッド | 分析対象の細胞を含む試料流体の調製に用いる使い捨てカートリッジ |
| FI20115785A0 (fi) | 2011-08-08 | 2011-08-08 | Thermo Fisher Scientific Oy | Menetelmä ja laite automaattiseen analyysiin |
| WO2013021101A1 (en) | 2011-08-08 | 2013-02-14 | Thermo Fisher Scientific Oy | Method and apparatus for automated analysis |
| FR2986617B1 (fr) * | 2012-02-02 | 2015-03-27 | Horiba Abx Sas | Dispositif et procede pour effectuer des mesures hematologiques et biochimiques a partir d'un echantillon biologique |
| JP5805136B2 (ja) * | 2013-05-16 | 2015-11-04 | 株式会社堀場製作所 | 全血血球免疫測定装置 |
| EP3955042B1 (en) | 2013-08-26 | 2024-08-21 | S.D. Sight Diagnostics Ltd. | Digital microscopy systems, methods and computer program products |
| AU2016322966B2 (en) | 2015-09-17 | 2021-10-14 | S.D. Sight Diagnostics Ltd | Methods and apparatus for detecting an entity in a bodily sample |
| WO2017168411A1 (en) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Image processing device for identifying blood parasites |
| CN109564209B (zh) * | 2016-05-11 | 2022-05-31 | 思迪赛特诊断有限公司 | 对样品实施的光学测量 |
| US11307196B2 (en) | 2016-05-11 | 2022-04-19 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
| CN107817208B (zh) * | 2016-09-12 | 2024-07-02 | 深圳市帝迈生物技术有限公司 | 一种血细胞计数装置及其白细胞计数修正方法 |
| EP3710810B1 (en) | 2017-11-14 | 2023-09-06 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
| WO2021042319A1 (zh) * | 2019-09-05 | 2021-03-11 | 深圳迈瑞生物医疗电子股份有限公司 | 血液细胞分析仪的分析方法和血液细胞分析仪 |
| JP7677972B2 (ja) | 2019-12-12 | 2025-05-15 | エス．ディー．サイト ダイアグノスティックス リミテッド | カラー血液スミア画像の人工的な生成 |
| AU2020400401A1 (en) | 2019-12-12 | 2022-06-02 | S.D. Sight Diagnostics Ltd | Analyzing an analyte disposed within a medium |
| CN113820260B (zh) * | 2021-09-30 | 2023-07-18 | 深圳市科曼医疗设备有限公司 | 用户状态检测方法、装置、设备和介质 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3649204A (en) * | 1968-09-18 | 1972-03-14 | Farr Devices Inc | Metering pump for analytical samples |
| US3893767A (en) * | 1973-10-23 | 1975-07-08 | Coulter Electronics | Electro-optical system for cancellation of the effects of red blood cells in a sample of biological cells |
| JPS5424680B2 (enExample) * | 1973-11-13 | 1979-08-22 | ||
| US3861877A (en) * | 1974-01-21 | 1975-01-21 | Clinical Technology Inc | Optical analysis of fluids |
| US3923397A (en) * | 1974-05-29 | 1975-12-02 | Dolive Stephen E | Hematocrit measuring method |
| US3901658A (en) * | 1974-07-30 | 1975-08-26 | Us Energy | Whole blood analysis rotor assembly having removable cellular sedimentation bowl |
| US4189927A (en) * | 1978-06-27 | 1980-02-26 | Westinghouse Electric Corp. | Condenser vacuum load compensating system |
-
1975
- 1975-02-28 JP JP50024531A patent/JPS5916667B2/ja not_active Expired
-
1976
- 1976-02-17 US US05/658,578 patent/US4030888A/en not_active Expired - Lifetime
- 1976-02-23 GB GB6969/76A patent/GB1503246A/en not_active Expired
- 1976-02-25 NL NL7601910A patent/NL7601910A/xx active Search and Examination
- 1976-02-25 FR FR7605278A patent/FR2302525A1/fr active Granted
- 1976-02-27 DE DE2608192A patent/DE2608192B2/de not_active Ceased
- 1976-02-27 IT IT67454/76A patent/IT1070234B/it active
- 1976-02-27 BR BR1293/76A patent/BR7601293A/pt unknown
- 1976-02-27 BR BR7601292A patent/BR7601292A/pt unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0187644A3 (en) * | 1985-01-06 | 1987-12-02 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem | A method and apparatus for the localization of bleeding in the gastrointestinal tract |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2302525A1 (fr) | 1976-09-24 |
| BR7601293A (pt) | 1976-09-14 |
| JPS5199596A (enExample) | 1976-09-02 |
| NL7601910A (nl) | 1976-08-31 |
| GB1503246A (en) | 1978-03-08 |
| BR7601292A (pt) | 1976-09-14 |
| DE2608192A1 (de) | 1976-09-09 |
| US4030888A (en) | 1977-06-21 |
| IT1070234B (it) | 1985-03-29 |
| JPS5916667B2 (ja) | 1984-04-17 |
| FR2302525B1 (enExample) | 1980-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8228 | New agent |
Free format text: HENKEL, G., DR.PHIL. FEILER, L., DR.RER.NAT. HAENZEL, W., DIPL.-ING., PAT.-ANW., 8000 MUENCHEN |
|
| 8235 | Patent refused |