DE2514322A1 - Neue cephalosporinderivate - Google Patents

Neue cephalosporinderivate

Info

Publication number
DE2514322A1
DE2514322A1 DE19752514322 DE2514322A DE2514322A1 DE 2514322 A1 DE2514322 A1 DE 2514322A1 DE 19752514322 DE19752514322 DE 19752514322 DE 2514322 A DE2514322 A DE 2514322A DE 2514322 A1 DE2514322 A1 DE 2514322A1
Authority
DE
Germany
Prior art keywords
ring
group
carboxylic acid
mixture
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19752514322
Other languages
German (de)
English (en)
Inventor
Masaharu Fujimoto
Ichiro Isaka
Masaru Iwanami
Norio Kawahara
Tetsuya Maeda
Masuo Murakami
Yoshinobu Nagano
Tadao Shibanuma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP49038545A external-priority patent/JPS5953276B2/ja
Priority claimed from JP4188474A external-priority patent/JPS50140480A/ja
Priority claimed from JP6312474A external-priority patent/JPS50154282A/ja
Priority claimed from JP6477474A external-priority patent/JPS604191B2/ja
Priority claimed from JP49116976A external-priority patent/JPS5143785A/ja
Priority claimed from JP11963874A external-priority patent/JPS5148686A/ja
Priority claimed from JP50013200A external-priority patent/JPS5188988A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of DE2514322A1 publication Critical patent/DE2514322A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE19752514322 1974-04-05 1975-04-02 Neue cephalosporinderivate Pending DE2514322A1 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP49038545A JPS5953276B2 (ja) 1974-04-05 1974-04-05 新セフアロスポリン誘導体の製造方法
JP4188474A JPS50140480A (enExample) 1974-04-15 1974-04-15
JP6312474A JPS50154282A (enExample) 1974-06-04 1974-06-04
JP6477474A JPS604191B2 (ja) 1974-06-07 1974-06-07 セフアロスポラン酸新誘導体の合成方法
JP49116976A JPS5143785A (en) 1974-10-11 1974-10-11 Shinsefuarosuhorinkanrenkagobutsuno goseiho
JP11963874A JPS5148686A (ja) 1974-10-17 1974-10-17 Shinsefuarosuhorinkanrenkagobutsuno goseihoho
JP50013200A JPS5188988A (enExample) 1975-01-31 1975-01-31

Publications (1)

Publication Number Publication Date
DE2514322A1 true DE2514322A1 (de) 1975-10-09

Family

ID=27563645

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752514322 Pending DE2514322A1 (de) 1974-04-05 1975-04-02 Neue cephalosporinderivate

Country Status (4)

Country Link
DE (1) DE2514322A1 (enExample)
DK (1) DK143875A (enExample)
FR (1) FR2266507B1 (enExample)
GB (1) GB1509074A (enExample)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2539664A1 (de) * 1974-09-06 1976-03-18 Sumitomo Chemical Co Cephalosporin-derivate
US4101656A (en) 1976-07-12 1978-07-18 Smithkline Corporation 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4112088A (en) * 1976-03-11 1978-09-05 Smithkline Corporation 7-Acyl-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins
US4118490A (en) 1976-05-19 1978-10-03 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl)cephalosporins and pharmaceutical compositions containing them
US4286089A (en) 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4576937A (en) * 1984-02-29 1986-03-18 Smithkline Beckman Corporation 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt
US5180719A (en) * 1988-10-24 1993-01-19 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
US5387748A (en) * 1988-10-24 1995-02-07 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial dithiocarbamoyl quinolones
US5434147A (en) * 1988-10-24 1995-07-18 Proctor & Gamble Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
US5491139A (en) * 1988-10-24 1996-02-13 The Procter & Gamble Company Antimicrobial quinolonyl lactams
US5530116A (en) * 1990-04-18 1996-06-25 The Procter & Gamble Company Antimicrobial quinolonyl lactams
US5637580A (en) * 1988-10-24 1997-06-10 The Procter & Gamble Company Antimicrobial penem-quinolones

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS545974A (en) * 1977-06-16 1979-01-17 Ajinomoto Co Inc Imidazoledicaroboxylic acid derivatives
US4117124A (en) * 1977-06-30 1978-09-26 Smithkline Corporation 7-Acylamino-3-[[3-(carboxymethyl)thio-1H-1,2,4-triazol-5-yl]thiomethyl]-3-cephem-4-carboxylic acids
JPS55129287A (en) * 1979-03-27 1980-10-06 Ajinomoto Co Inc Imidazole-dicarboxylic acid derivative
CN114671892B (zh) * 2022-04-24 2023-04-11 江苏海洋大学 含7-氨基头孢烷酸的1,3,4-噻二唑衍生物及制法与用途

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2539664A1 (de) * 1974-09-06 1976-03-18 Sumitomo Chemical Co Cephalosporin-derivate
US4286089A (en) 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4112088A (en) * 1976-03-11 1978-09-05 Smithkline Corporation 7-Acyl-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins
US4130644A (en) 1976-03-11 1978-12-19 Smithkline Corporation 7-Acylamine-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins and pharmaceutical compositions containing them
US4138556A (en) 1976-03-11 1979-02-06 Smithkline Corporation 7-Amino-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins
US4118490A (en) 1976-05-19 1978-10-03 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl)cephalosporins and pharmaceutical compositions containing them
US4101656A (en) 1976-07-12 1978-07-18 Smithkline Corporation 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4576937A (en) * 1984-02-29 1986-03-18 Smithkline Beckman Corporation 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt
US5387748A (en) * 1988-10-24 1995-02-07 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial dithiocarbamoyl quinolones
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
US5180719A (en) * 1988-10-24 1993-01-19 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
US5434147A (en) * 1988-10-24 1995-07-18 Proctor & Gamble Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
US5491139A (en) * 1988-10-24 1996-02-13 The Procter & Gamble Company Antimicrobial quinolonyl lactams
US5631256A (en) * 1988-10-24 1997-05-20 The Procter & Gamble Company Antimicrobial quinolone thioureas
US5637580A (en) * 1988-10-24 1997-06-10 The Procter & Gamble Company Antimicrobial penem-quinolones
US5646139A (en) * 1988-10-24 1997-07-08 The Procter & Gamble Company Antimicrobial carbapenem quinolones
US5648346A (en) * 1988-10-24 1997-07-15 The Procter & Gamble Company Antimicrobial carbacephem-quinolones
US5656623A (en) * 1988-10-24 1997-08-12 The Procter & Gamble Company Antimicrobial lactam-quinolones
US5672600A (en) * 1988-10-24 1997-09-30 The Procter & Gamble Company Antimicrobial dithiocarbamoyl quinolones
US5530116A (en) * 1990-04-18 1996-06-25 The Procter & Gamble Company Antimicrobial quinolonyl lactams

Also Published As

Publication number Publication date
FR2266507A1 (enExample) 1975-10-31
DK143875A (enExample) 1975-10-06
GB1509074A (en) 1978-04-26
FR2266507B1 (enExample) 1978-11-10

Similar Documents

Publication Publication Date Title
DE2461478C2 (de) Cephalosporinderivate und Verfahren zu deren Herstellung
CH630386A5 (de) Verfahren zur herstellung von neuen cephalosporinderivaten.
DE1795838B2 (de) Cephalosporinderivate
DE2439880C3 (de) (6R, 7R)-3-Carbamoyloxymethyl-7- [2-(fur-2-yl)-2methoxyiminoacetamido] -ceph-S-em^carbonsäure und Verfahren zur ihrer Herstellung
DE3233376A1 (de) Cephalosporinchinoliniumbetaine und sie enthaltende pharmazeutische mittel
DE2922036C2 (de) 7-[2-(2-Amino-4-thiazolyl)-2-methoxyimino-acetamido]- cephalosporansäure-Derivate
CH648317A5 (de) 7alpha-methoxy-7betha-(1,3-dithietan-2- carboxamido)cephalosporansaeurederivate und verfahren zu ihrer herstellung.
DD284807A5 (de) Verf. z. herstellung eine pyhsikalischen gemisches aus mindestens einem salz des ((1-methyl-1-pyrrolidinio)- methyl)-3-cephem-4-carboxylats u. einer pharmazeutisch vertraeglichen, nicht toxischen, organischen oder anorganischen base
DE2362816A1 (de) Mit heterocyclischer acylgruppe substituierte cephalosporinderivate
DE3233377A1 (de) Cephalosporinisochinoliniumbetaine und sie enthaltende pharmazeutische mittel
DD215552A5 (de) Verfahren zur herstellung von kristallisierten cephem-saeureadditionssalzen
DD209633A5 (de) Verfahren zur herstellung von 3-thienopyridinium- und 3-furopyridiniumcephalosporinen
DE2539664A1 (de) Cephalosporin-derivate
CH654313A5 (de) Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutische mittel, die diese verbindungen enthalten.
US4068074A (en) Cephalosporin derivatives having at the 3-position of the cephem ring a heterocyclic thiomethyl group with a carboxy or sulfo group and at the 7-position of the cephem ring an α-heterocylic acylaminophenyl-acetamide group
EP0111934A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DE2739448A1 (de) 7-substituierte aminoacetamido- oxadethiacephalosporine, verfahren zu deren herstellung und deren verwendung bei der behandlung bakterieller erkrankungen
DE2738711A1 (de) Cephalosporinderivate
DE2715038A1 (de) Neue antibakterielle verbindungen
DE2727325A1 (de) 7- eckige klammer auf alpha-(2,3- dihydro-2-oxo-1h-benzimidazol-1-ylcarbonylamino)arylacetamido eckige klammer zu cephalosporine
DE2700271A1 (de) Thienopyridinderivate
DE3037284A1 (de) Penicillinverbindungen und verfahren zu deren herstellung, sowie arzneimittel welche diese enthalten
DD204257A5 (de) Verfahren zur herstellung von cephalosporinen, die in position 3 substituiert sind
DE2638028A1 (de) Neue cephalosporinverbindungen
DE2714419C2 (de) Cephalosporinderivate, Verfahren zu deren Herstellung und Arzneimittel

Legal Events

Date Code Title Description
OHJ Non-payment of the annual fee