DE2456311A1 - Benzodiazepinderivate - Google Patents

Benzodiazepinderivate

Info

Publication number
DE2456311A1
DE2456311A1 DE19742456311 DE2456311A DE2456311A1 DE 2456311 A1 DE2456311 A1 DE 2456311A1 DE 19742456311 DE19742456311 DE 19742456311 DE 2456311 A DE2456311 A DE 2456311A DE 2456311 A1 DE2456311 A1 DE 2456311A1
Authority
DE
Germany
Prior art keywords
alkyl
methyl
general formula
denotes
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19742456311
Other languages
German (de)
English (en)
Inventor
Rodney Ian Fryer
Armin Walser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/419,582 external-priority patent/US3989681A/en
Priority claimed from US420119A external-priority patent/US3868362A/en
Priority claimed from US420118A external-priority patent/US3865815A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE2456311A1 publication Critical patent/DE2456311A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C45/16—Making multilayered or multicoloured articles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE19742456311 1973-11-28 1974-11-28 Benzodiazepinderivate Pending DE2456311A1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US41956373A 1973-11-28 1973-11-28
US05/419,582 US3989681A (en) 1973-11-28 1973-11-28 7-Azoxy substituted-1,4-benzodiazepin-2-ones
US420119A US3868362A (en) 1973-11-29 1973-11-29 Oxazolobenzodiazepines
US420118A US3865815A (en) 1973-11-29 1973-11-29 7-Hydroxyamino-1,4-benzodiazepines

Publications (1)

Publication Number Publication Date
DE2456311A1 true DE2456311A1 (de) 1975-06-05

Family

ID=27503678

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19742456311 Pending DE2456311A1 (de) 1973-11-28 1974-11-28 Benzodiazepinderivate

Country Status (3)

Country Link
JP (1) JPS5084590A (enExample)
DE (1) DE2456311A1 (enExample)
FR (1) FR2252103A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0033974A1 (de) * 1980-02-08 1981-08-19 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Benzodiazepin-Derivate, Zwischenprodukte und Verfahren für ihre Herstellung, ihre Verwendung, sowie diese enthaltende Arzneimittel
EP0033973A1 (de) * 1980-02-08 1981-08-19 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Benzodiazepin-Derivate, Zwischenprodukte und Verfahren für ihre Herstellung, ihre Verwendung, sowie diese enthaltende Arzneimittel
EP0240899A3 (en) * 1986-04-01 1989-05-10 Boehringer Ingelheim Kg 1,4-diazepine

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA794014B (en) * 1978-08-11 1980-05-28 Hoffmann La Roche Benzodiazepine derivatives
CA1114373A (en) * 1978-08-11 1981-12-15 Albert E. Fischli Benzodiazepine derivatives
JPS5572177A (en) * 1978-11-27 1980-05-30 Shionogi & Co Ltd 4,1-benzoxazepine or 4,1-benzothiazepine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0033974A1 (de) * 1980-02-08 1981-08-19 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Benzodiazepin-Derivate, Zwischenprodukte und Verfahren für ihre Herstellung, ihre Verwendung, sowie diese enthaltende Arzneimittel
EP0033973A1 (de) * 1980-02-08 1981-08-19 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Benzodiazepin-Derivate, Zwischenprodukte und Verfahren für ihre Herstellung, ihre Verwendung, sowie diese enthaltende Arzneimittel
EP0240899A3 (en) * 1986-04-01 1989-05-10 Boehringer Ingelheim Kg 1,4-diazepine

Also Published As

Publication number Publication date
FR2252103A1 (en) 1975-06-20
FR2252103B1 (enExample) 1977-11-10
JPS5084590A (enExample) 1975-07-08

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Legal Events

Date Code Title Description
OHJ Non-payment of the annual fee