DE2365992C3 - 6α-Fluor-17,21-dihydroxy-16β-methylpregna-4,9(11)-dien-3,20-dion-17,21-diacetat und Verfahren zu dessen Herstellung - Google Patents
6α-Fluor-17,21-dihydroxy-16β-methylpregna-4,9(11)-dien-3,20-dion-17,21-diacetat und Verfahren zu dessen HerstellungInfo
- Publication number
- DE2365992C3 DE2365992C3 DE2365992A DE2365992A DE2365992C3 DE 2365992 C3 DE2365992 C3 DE 2365992C3 DE 2365992 A DE2365992 A DE 2365992A DE 2365992 A DE2365992 A DE 2365992A DE 2365992 C3 DE2365992 C3 DE 2365992C3
- Authority
- DE
- Germany
- Prior art keywords
- dione
- diene
- fluoro
- methylpregna
- dihydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23333772A | 1972-03-09 | 1972-03-09 | |
| US31697372A | 1972-12-20 | 1972-12-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2365992A1 DE2365992A1 (de) | 1977-05-18 |
| DE2365992B2 DE2365992B2 (de) | 1981-08-06 |
| DE2365992C3 true DE2365992C3 (de) | 1982-05-19 |
Family
ID=26926821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2365992A Expired DE2365992C3 (de) | 1972-03-09 | 1973-02-22 | 6α-Fluor-17,21-dihydroxy-16β-methylpregna-4,9(11)-dien-3,20-dion-17,21-diacetat und Verfahren zu dessen Herstellung |
Country Status (13)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1430223A (en) * | 1973-10-25 | 1976-03-31 | Upjohn Co | Anti-inflammatory composition comprising steroids |
| ZA77943B (en) * | 1976-03-19 | 1977-12-28 | Upjohn Co | Topical steroid clindamycin preparations |
| NL187577C (nl) * | 1978-04-05 | 1991-11-18 | Sibla Srl | 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen. |
| DE3068965D1 (en) | 1979-11-16 | 1984-09-20 | Sterosynt Ltd | 6-alpha-fluoro-16-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them |
| JPH0240957Y2 (US07118763-20061010-C00002.png) * | 1986-08-30 | 1990-10-31 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB933859A (US07118763-20061010-C00002.png) * | 1958-09-06 | 1963-08-14 | Syntex S.A. |
-
1973
- 1973-02-22 GB GB877373A patent/GB1403962A/en not_active Expired
- 1973-02-22 DE DE2365992A patent/DE2365992C3/de not_active Expired
- 1973-02-26 CH CH396076A patent/CH580118A5/xx not_active IP Right Cessation
- 1973-02-26 CH CH277073A patent/CH580116A5/xx not_active IP Right Cessation
- 1973-02-26 CH CH395976A patent/CH580117A5/xx not_active IP Right Cessation
- 1973-02-26 AU AU52579/73A patent/AU468257B2/en not_active Expired
- 1973-03-02 ES ES412235A patent/ES412235A1/es not_active Expired
- 1973-03-07 AR AR246918A patent/AR197216A1/es active
- 1973-03-07 JP JP2625073A patent/JPS5331156B2/ja not_active Expired
- 1973-03-08 FR FR7308331A patent/FR2181802B1/fr not_active Expired
- 1973-03-08 NL NL7303262.A patent/NL165178C/xx not_active IP Right Cessation
- 1973-03-08 DK DK128173AA patent/DK133382B/da unknown
- 1973-03-08 SE SE7303287A patent/SE396756B/xx unknown
-
1976
- 1976-05-06 PH PH18405A patent/PH14703A/en unknown
- 1976-09-09 JP JP51107346A patent/JPS5227760A/ja active Granted
- 1976-09-09 JP JP51107347A patent/JPS5227761A/ja active Granted
-
1980
- 1980-11-06 HK HK626/80A patent/HK62680A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OD | Request for examination | ||
| AC | Divided out of |
Ref country code: DE Ref document number: 2308731 Format of ref document f/p: P |
|
| C3 | Grant after two publication steps (3rd publication) | ||
| 8339 | Ceased/non-payment of the annual fee |