DE2360550A1 - Indenylaethyltetrazole, -sulfonsaeuren und -phosphorsaeuren - Google Patents

Indenylaethyltetrazole, -sulfonsaeuren und -phosphorsaeuren

Info

Publication number
DE2360550A1
DE2360550A1 DE2360550A DE2360550A DE2360550A1 DE 2360550 A1 DE2360550 A1 DE 2360550A1 DE 2360550 A DE2360550 A DE 2360550A DE 2360550 A DE2360550 A DE 2360550A DE 2360550 A1 DE2360550 A1 DE 2360550A1
Authority
DE
Germany
Prior art keywords
hydrogen
alkyl
methyl
halogen
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE2360550A
Other languages
German (de)
English (en)
Inventor
Howard Jones
Tsung-Ying Shen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2360550A1 publication Critical patent/DE2360550A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/383—Cycloaliphatic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3882—Arylalkanephosphonic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
DE2360550A 1972-12-06 1973-12-05 Indenylaethyltetrazole, -sulfonsaeuren und -phosphorsaeuren Ceased DE2360550A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US312549A US3860636A (en) 1972-12-06 1972-12-06 Substituted indenyl phosphonic acids having anti-inflammatory activity

Publications (1)

Publication Number Publication Date
DE2360550A1 true DE2360550A1 (de) 1974-06-12

Family

ID=23211967

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2360550A Ceased DE2360550A1 (de) 1972-12-06 1973-12-05 Indenylaethyltetrazole, -sulfonsaeuren und -phosphorsaeuren

Country Status (7)

Country Link
US (1) US3860636A (enExample)
JP (1) JPS4986353A (enExample)
CH (1) CH613688A5 (enExample)
DE (1) DE2360550A1 (enExample)
FR (1) FR2209562B1 (enExample)
GB (1) GB1418950A (enExample)
NL (1) NL7316014A (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2511378A1 (fr) * 1981-08-14 1983-02-18 London Polytech Nouveaux aminoacides isomeres, leur preparation et leur application en medecine
FR2511379A1 (fr) * 1981-08-14 1983-02-18 London Polytech Nouveaux aminoacides isomeres, leur preparation et leur application medicale

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047578A (en) * 1987-08-07 1991-09-10 The Dow Chemical Company Novel phosphonic acid compounds and method of preparation
US5371284A (en) * 1987-09-03 1994-12-06 Schering Corporation Phenyl acetylenic acetals
US6063818A (en) * 1996-06-13 2000-05-16 Cell Pathways Inc. Substituted benzylidene indenyl formamides, acetamides and propionamides
US6121321A (en) * 1996-06-13 2000-09-19 Cell Pathways, Inc. Substituted methoxy benzylidene indenyl acetic and propionic acids for treating patients with precancerous lesions
US5998477A (en) * 1996-06-13 1999-12-07 Cell Pathways Inc. Substituted methoxy benzylidene indenyl-acetic and propionic acids for treating patients with precancerous lesions
US5965619A (en) * 1996-06-13 1999-10-12 Cell Pathways Inc. Method for treating patients having precancerous lesions with substituted indene derivatives
US5948779A (en) * 1997-12-12 1999-09-07 Cell Pathways, Inc. Substituted condensation products of n-benzyl-3-indenyl acetamides with heterocyclic aldehydes
US6028116A (en) * 1998-04-03 2000-02-22 Cell Pathways, Inc. Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia
US6479493B1 (en) 2001-08-23 2002-11-12 Cell Pathways, Inc. Methods for treatment of type I diabetes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3622619A (en) * 1968-07-31 1971-11-23 Merck & Co Inc Biphenyl compounds
US3714232A (en) * 1969-06-25 1973-01-30 Merck & Co Inc 5-arylphenyl sulfonic acids
US3671580A (en) * 1969-12-22 1972-06-20 Merck & Co Inc Substituted biphenyl acetic acids and ester derivatives thereof
US3754019A (en) * 1970-04-20 1973-08-21 Merck & Co Inc 5-arylphenylphosphonic and phosphonous acids
US3647858A (en) * 1970-05-01 1972-03-07 Merck & Co Inc Process for preparing 1-benzylidene-3-indenyl acetic acids
US3654349A (en) * 1970-05-01 1972-04-04 Merck & Co Inc Substituted indenyl acetic acids
US3732292A (en) * 1970-05-01 1973-05-08 Merck & Co Inc Indenyl compounds
NL7200060A (enExample) * 1971-01-21 1972-07-25
US3822310A (en) * 1971-01-21 1974-07-02 Merck & Co Inc Substituted indenyl acetic acids

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2511378A1 (fr) * 1981-08-14 1983-02-18 London Polytech Nouveaux aminoacides isomeres, leur preparation et leur application en medecine
FR2511379A1 (fr) * 1981-08-14 1983-02-18 London Polytech Nouveaux aminoacides isomeres, leur preparation et leur application medicale

Also Published As

Publication number Publication date
CH613688A5 (enExample) 1979-10-15
JPS4986353A (enExample) 1974-08-19
FR2209562A1 (enExample) 1974-07-05
FR2209562B1 (enExample) 1978-11-10
US3860636A (en) 1975-01-14
NL7316014A (enExample) 1974-06-10
GB1418950A (en) 1975-12-24

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Legal Events

Date Code Title Description
8131 Rejection