DE2355324A1 - Neue prostaglandinderivate und verfahren zu ihrer herstellung - Google Patents

Neue prostaglandinderivate und verfahren zu ihrer herstellung

Info

Publication number
DE2355324A1
DE2355324A1 DE19732355324 DE2355324A DE2355324A1 DE 2355324 A1 DE2355324 A1 DE 2355324A1 DE 19732355324 DE19732355324 DE 19732355324 DE 2355324 A DE2355324 A DE 2355324A DE 2355324 A1 DE2355324 A1 DE 2355324A1
Authority
DE
Germany
Prior art keywords
trans
hydroxy
methyl
compounds
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19732355324
Other languages
German (de)
English (en)
Inventor
Pierre Crabbe
John H Fried
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US368983A external-priority patent/US3879438A/en
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Publication of DE2355324A1 publication Critical patent/DE2355324A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19732355324 1972-11-14 1973-11-06 Neue prostaglandinderivate und verfahren zu ihrer herstellung Withdrawn DE2355324A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30641472A 1972-11-14 1972-11-14
US33832573A 1973-03-05 1973-03-05
US368983A US3879438A (en) 1973-03-05 1973-06-11 4,5,13-Prostatrienoic acid derivatives

Publications (1)

Publication Number Publication Date
DE2355324A1 true DE2355324A1 (de) 1974-05-22

Family

ID=27405167

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19732355324 Withdrawn DE2355324A1 (de) 1972-11-14 1973-11-06 Neue prostaglandinderivate und verfahren zu ihrer herstellung

Country Status (6)

Country Link
JP (1) JPS4993341A (enrdf_load_stackoverflow)
DE (1) DE2355324A1 (enrdf_load_stackoverflow)
ES (1) ES420519A2 (enrdf_load_stackoverflow)
FR (1) FR2206096B2 (enrdf_load_stackoverflow)
GB (1) GB1414383A (enrdf_load_stackoverflow)
IL (1) IL42670A (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258057A (en) * 1978-07-08 1981-03-24 Hoechst Aktiengesellschaft Prostaglandin derivatives of the Δ2,4-11-deoxy-PEG series

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3414509A1 (de) * 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 9-halogen-prostaglandine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258057A (en) * 1978-07-08 1981-03-24 Hoechst Aktiengesellschaft Prostaglandin derivatives of the Δ2,4-11-deoxy-PEG series

Also Published As

Publication number Publication date
FR2206096A2 (enrdf_load_stackoverflow) 1974-06-07
GB1414383A (en) 1975-11-19
IL42670A0 (en) 1973-10-25
ES420519A2 (es) 1977-03-01
IL42670A (en) 1977-01-31
JPS4993341A (enrdf_load_stackoverflow) 1974-09-05
AU5776373A (en) 1975-01-09
FR2206096B2 (enrdf_load_stackoverflow) 1977-03-11

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination