DE2217230A1 - Verfahren und Vorrichtung zum Messen kleiner Mengen einer gasförmigen oder flüssigen Probe - Google Patents
Verfahren und Vorrichtung zum Messen kleiner Mengen einer gasförmigen oder flüssigen ProbeInfo
- Publication number
- DE2217230A1 DE2217230A1 DE19722217230 DE2217230A DE2217230A1 DE 2217230 A1 DE2217230 A1 DE 2217230A1 DE 19722217230 DE19722217230 DE 19722217230 DE 2217230 A DE2217230 A DE 2217230A DE 2217230 A1 DE2217230 A1 DE 2217230A1
- Authority
- DE
- Germany
- Prior art keywords
- liquid
- holder
- area
- capillary
- attached
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 title claims description 46
- 238000000034 method Methods 0.000 title claims description 19
- 230000001681 protective effect Effects 0.000 claims description 28
- 239000000463 material Substances 0.000 claims description 19
- 210000004369 blood Anatomy 0.000 claims description 18
- 239000008280 blood Substances 0.000 claims description 18
- 239000004927 clay Substances 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 9
- 238000009423 ventilation Methods 0.000 claims description 8
- 239000000654 additive Substances 0.000 claims description 2
- 230000000996 additive effect Effects 0.000 claims description 2
- 238000005119 centrifugation Methods 0.000 claims description 2
- 239000003566 sealing material Substances 0.000 claims 6
- 239000000853 adhesive Substances 0.000 claims 5
- 230000001070 adhesive effect Effects 0.000 claims 5
- 239000013013 elastic material Substances 0.000 claims 3
- 238000007789 sealing Methods 0.000 claims 3
- 238000005452 bending Methods 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000012858 resilient material Substances 0.000 claims 1
- 239000012071 phase Substances 0.000 description 11
- 210000002381 plasma Anatomy 0.000 description 9
- 210000002966 serum Anatomy 0.000 description 6
- 210000000601 blood cell Anatomy 0.000 description 5
- 210000003811 finger Anatomy 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 210000005224 forefinger Anatomy 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000007792 gaseous phase Substances 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0605—Metering of fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0838—Capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S138/00—Pipes and tubular conduits
- Y10S138/11—Shape
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14787871A | 1971-05-28 | 1971-05-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2217230A1 true DE2217230A1 (de) | 1972-12-07 |
Family
ID=22523290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19722217230 Pending DE2217230A1 (de) | 1971-05-28 | 1972-04-11 | Verfahren und Vorrichtung zum Messen kleiner Mengen einer gasförmigen oder flüssigen Probe |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3779083A (enExample) |
| DE (1) | DE2217230A1 (enExample) |
| DK (1) | DK146608C (enExample) |
| FR (1) | FR2139813B1 (enExample) |
| GB (1) | GB1323398A (enExample) |
| IT (1) | IT952214B (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0060440A1 (de) * | 1981-03-13 | 1982-09-22 | Dr. Karl Thomae GmbH | Aufklappbares Klemmstück mit Balgaufsatz zur Aufnahme eines Röhrchens |
| WO2010094440A1 (de) | 2009-02-17 | 2010-08-26 | Roche Diagnostics Gmbh | Verfahren und vorrichtung zur bereitstellung von blutbestandteilen |
| CN112547144A (zh) * | 2020-11-13 | 2021-03-26 | 青岛大学附属医院 | 一种存放和加入样本稳定剂的毛细管 |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3859051A (en) * | 1973-08-16 | 1975-01-07 | Rohe Scientific Corp | Means for transferring a liquid in a capillary open at both ends to an analyzing system |
| US3915652A (en) * | 1973-08-16 | 1975-10-28 | Samuel Natelson | Means for transferring a liquid in a capillary open at both ends to an analyzing system |
| US4003262A (en) * | 1974-12-16 | 1977-01-18 | Becton, Dickinson And Company | Apparatus for measuring precise micro quantities of fluid samples |
| US3965750A (en) * | 1975-02-21 | 1976-06-29 | Julius Theodore Johnson | Liquid sampler and sterilizer |
| US3986834A (en) * | 1975-06-04 | 1976-10-19 | Becton, Dickinson And Company | Method for detecting blood urea nitrogen |
| DE2553613C3 (de) * | 1975-11-28 | 1978-11-23 | Compur-Electronic Gmbh, 8000 Muenchen | Verfahren zur Vorbereitung von Meßflüssigkeiten |
| US4275591A (en) * | 1977-07-25 | 1981-06-30 | Becton, Dickinson And Company | Protective shield for capillary pipette |
| US4435989A (en) | 1980-07-03 | 1984-03-13 | Beckman Instruments, Inc. | Plunger operated pipet |
| US4442722A (en) * | 1982-02-23 | 1984-04-17 | Beckman Instruments Inc. | Plunger operated pipet |
| US5417925A (en) * | 1993-04-16 | 1995-05-23 | Beckman Instruments, Inc. | Capillary and capillary retaining system |
| US5605666A (en) * | 1993-04-16 | 1997-02-25 | Beckman Instruments, Inc. | Capillary retaining system |
| NL1037672C2 (nl) * | 2010-02-01 | 2011-08-03 | Eurotrol B V | Werkwijze voor het bepalen van de betrouwbaarheid van een inrichting voor het meten van de concentratie van een stof in volledig bloed, werkwijze voor het behandelen van volledig bloed, houder en kit. |
| US20120101407A1 (en) * | 2010-10-21 | 2012-04-26 | Inovx, Llc | Apparatus and method for preparation of small volume of samples |
| CN108562345B (zh) * | 2018-04-11 | 2024-01-30 | 佛山科学技术学院 | 一种精确测量微量液体的装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2540360A (en) * | 1946-11-12 | 1951-02-06 | George B Ulvild | Pipette loader |
| NL275145A (enExample) * | 1958-03-13 | 1962-02-22 | ||
| NL137565C (enExample) * | 1965-07-15 | |||
| US3416361A (en) * | 1966-06-23 | 1968-12-17 | Clay Adams Inc | Microhematocrit tube |
| US3464800A (en) * | 1966-10-27 | 1969-09-02 | Horace W Gerarde | Pipette assembly having precise quantity of dry stabilized reagent and method of preparing same |
| US3626762A (en) * | 1969-08-12 | 1971-12-14 | Gilford Instr Labor Inc | Method and apparatus for filling a capillary tube with liquid |
-
1971
- 1971-05-28 US US00147878A patent/US3779083A/en not_active Expired - Lifetime
-
1972
- 1972-02-22 GB GB816972A patent/GB1323398A/en not_active Expired
- 1972-03-11 IT IT48923/72A patent/IT952214B/it active
- 1972-03-20 FR FR727209629A patent/FR2139813B1/fr not_active Expired
- 1972-04-11 DE DE19722217230 patent/DE2217230A1/de active Pending
- 1972-05-25 DK DK259372A patent/DK146608C/da not_active IP Right Cessation
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0060440A1 (de) * | 1981-03-13 | 1982-09-22 | Dr. Karl Thomae GmbH | Aufklappbares Klemmstück mit Balgaufsatz zur Aufnahme eines Röhrchens |
| WO2010094440A1 (de) | 2009-02-17 | 2010-08-26 | Roche Diagnostics Gmbh | Verfahren und vorrichtung zur bereitstellung von blutbestandteilen |
| EP2223747A1 (de) * | 2009-02-17 | 2010-09-01 | Roche Diagnostics GmbH | Verfahren und Vorrichtung zur Bereitstellung von Blutbestandteilen |
| CN102316989A (zh) * | 2009-02-17 | 2012-01-11 | 霍夫曼-拉罗奇有限公司 | 用于提供血液组分的方法和装置 |
| CN102316989B (zh) * | 2009-02-17 | 2014-08-27 | 霍夫曼-拉罗奇有限公司 | 用于提供血液组分的方法和装置 |
| CN112547144A (zh) * | 2020-11-13 | 2021-03-26 | 青岛大学附属医院 | 一种存放和加入样本稳定剂的毛细管 |
Also Published As
| Publication number | Publication date |
|---|---|
| DK146608B (da) | 1983-11-14 |
| DK146608C (da) | 1984-05-28 |
| IT952214B (it) | 1973-07-20 |
| FR2139813B1 (enExample) | 1973-07-13 |
| US3779083A (en) | 1973-12-18 |
| GB1323398A (en) | 1973-07-11 |
| FR2139813A1 (enExample) | 1973-01-12 |
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