DE2127541A1 - Verfahren zur Herstellung von Zitronensäure durch submerse Gärung - Google Patents
Verfahren zur Herstellung von Zitronensäure durch submerse GärungInfo
- Publication number
- DE2127541A1 DE2127541A1 DE19712127541 DE2127541A DE2127541A1 DE 2127541 A1 DE2127541 A1 DE 2127541A1 DE 19712127541 DE19712127541 DE 19712127541 DE 2127541 A DE2127541 A DE 2127541A DE 2127541 A1 DE2127541 A1 DE 2127541A1
- Authority
- DE
- Germany
- Prior art keywords
- fermentation
- ions
- added
- citric acid
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000855 fermentation Methods 0.000 title claims description 32
- 230000004151 fermentation Effects 0.000 title claims description 32
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 title claims description 24
- 238000004519 manufacturing process Methods 0.000 title claims description 10
- 238000000034 method Methods 0.000 title claims description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 19
- 239000011780 sodium chloride Substances 0.000 claims description 10
- 235000015097 nutrients Nutrition 0.000 claims description 9
- 229910001220 stainless steel Inorganic materials 0.000 claims description 6
- 239000010935 stainless steel Substances 0.000 claims description 6
- 241000228245 Aspergillus niger Species 0.000 claims description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 238000011081 inoculation Methods 0.000 claims description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 3
- 239000003513 alkali Substances 0.000 claims description 3
- 239000003112 inhibitor Substances 0.000 claims description 3
- 150000002500 ions Chemical class 0.000 claims description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 3
- 229910001414 potassium ion Inorganic materials 0.000 claims description 3
- 239000000725 suspension Substances 0.000 claims description 3
- 229910000831 Steel Inorganic materials 0.000 claims description 2
- 229910001413 alkali metal ion Inorganic materials 0.000 claims description 2
- 235000014633 carbohydrates Nutrition 0.000 claims description 2
- 150000001720 carbohydrates Chemical class 0.000 claims description 2
- 238000010276 construction Methods 0.000 claims description 2
- 238000001816 cooling Methods 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- 229910052757 nitrogen Inorganic materials 0.000 claims description 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 2
- 229910001415 sodium ion Inorganic materials 0.000 claims description 2
- 239000010959 steel Substances 0.000 claims description 2
- -1 ammonium ions Chemical class 0.000 claims 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 12
- 239000002518 antifoaming agent Substances 0.000 description 5
- 239000002609 medium Substances 0.000 description 5
- 235000006408 oxalic acid Nutrition 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 239000000080 wetting agent Substances 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 150000004682 monohydrates Chemical class 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229910021655 trace metal ion Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/48—Tricarboxylic acids, e.g. citric acid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
- Y10S435/917—Aspergillus niger
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT763270A AT296194B (de) | 1970-08-21 | 1970-08-21 | Verfahren zur Herstellung von Zitronensäure durch submerse Gärung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2127541A1 true DE2127541A1 (de) | 1972-02-24 |
Family
ID=3598001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19712127541 Pending DE2127541A1 (de) | 1970-08-21 | 1971-06-03 | Verfahren zur Herstellung von Zitronensäure durch submerse Gärung |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3809612A (enExample) |
| JP (1) | JPS5328518B1 (enExample) |
| AT (1) | AT296194B (enExample) |
| AU (1) | AU460005B2 (enExample) |
| BE (1) | BE768493A (enExample) |
| CA (1) | CA973496A (enExample) |
| CH (1) | CH548449A (enExample) |
| DE (1) | DE2127541A1 (enExample) |
| FR (1) | FR2103983A5 (enExample) |
| GB (1) | GB1348798A (enExample) |
| IT (1) | IT941705B (enExample) |
| NL (1) | NL152930B (enExample) |
| SE (1) | SE392289B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT392799B (de) * | 1989-10-25 | 1991-06-10 | Jungbunzlauer Ag | Verfahren zur fermentativen herstellung von zitronensaeure aus kohlehydraten |
| FR3137856B1 (fr) | 2022-07-12 | 2024-07-12 | Seti Tec | Technique de perçage à moteurs à régulations adaptatives |
-
1970
- 1970-08-21 AT AT763270A patent/AT296194B/de not_active IP Right Cessation
-
1971
- 1971-06-03 DE DE19712127541 patent/DE2127541A1/de active Pending
- 1971-06-08 CH CH832071A patent/CH548449A/xx not_active IP Right Cessation
- 1971-06-09 NL NL717107925A patent/NL152930B/xx unknown
- 1971-06-14 BE BE768493A patent/BE768493A/xx unknown
- 1971-07-07 CA CA117,687A patent/CA973496A/en not_active Expired
- 1971-07-20 AU AU31765/71A patent/AU460005B2/en not_active Expired
- 1971-07-26 GB GB3496771A patent/GB1348798A/en not_active Expired
- 1971-07-29 FR FR7128672A patent/FR2103983A5/fr not_active Expired
- 1971-08-12 JP JP6067571A patent/JPS5328518B1/ja active Pending
- 1971-08-18 SE SE7110520A patent/SE392289B/xx unknown
- 1971-08-20 IT IT27680/71A patent/IT941705B/it active
- 1971-08-23 US US00174152A patent/US3809612A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NL152930B (nl) | 1977-04-15 |
| CH548449A (de) | 1974-04-30 |
| IT941705B (it) | 1973-03-10 |
| AU460005B2 (en) | 1975-03-20 |
| AU3176571A (en) | 1973-02-01 |
| AT296194B (de) | 1972-02-10 |
| CA973496A (en) | 1975-08-26 |
| BE768493A (fr) | 1971-11-03 |
| FR2103983A5 (enExample) | 1972-04-14 |
| US3809612A (en) | 1974-05-07 |
| SE392289B (sv) | 1977-03-21 |
| GB1348798A (en) | 1974-03-20 |
| JPS5328518B1 (enExample) | 1978-08-15 |
| NL7107925A (enExample) | 1972-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHN | Withdrawal |