DE2110396A1 - Substituierte Benzimidazole - Google Patents

Substituierte Benzimidazole

Info

Publication number
DE2110396A1
DE2110396A1 DE19712110396 DE2110396A DE2110396A1 DE 2110396 A1 DE2110396 A1 DE 2110396A1 DE 19712110396 DE19712110396 DE 19712110396 DE 2110396 A DE2110396 A DE 2110396A DE 2110396 A1 DE2110396 A1 DE 2110396A1
Authority
DE
Germany
Prior art keywords
alkoxy
radicals
thiazolyl
benzimidazole
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712110396
Other languages
German (de)
English (en)
Inventor
Fisher Michael Herbert
Hoff Dale Richard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2110396A1 publication Critical patent/DE2110396A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19712110396 1970-03-05 1971-03-04 Substituierte Benzimidazole Pending DE2110396A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1695770A 1970-03-05 1970-03-05
US14934271A 1971-06-02 1971-06-02

Publications (1)

Publication Number Publication Date
DE2110396A1 true DE2110396A1 (de) 1971-09-23

Family

ID=26689269

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712110396 Pending DE2110396A1 (de) 1970-03-05 1971-03-04 Substituierte Benzimidazole

Country Status (9)

Country Link
US (2) US3646049A (enExample)
AT (1) AT310738B (enExample)
BE (1) BE763781R (enExample)
CA (1) CA967962A (enExample)
CH (1) CH566344A5 (enExample)
DE (1) DE2110396A1 (enExample)
FR (1) FR2085671B1 (enExample)
GB (2) GB1328321A (enExample)
NL (2) NL7102896A (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1221596A (en) * 1967-12-06 1971-02-03 Merck & Co Inc Benzimidazole derivatives
US3922262A (en) * 1971-04-28 1975-11-25 Nippon Kayaku Kk N-Substituted derivatives of bleomycins
US3956488A (en) * 1973-09-27 1976-05-11 Merck & Co., Inc. Compositions and methods for the treatment of helminthiasis
GB1493931A (en) * 1974-02-07 1977-11-30 Smith Kline French Lab Guanidines isothioureas and thioureas
US4405621A (en) * 1974-02-07 1983-09-20 Smith Kline & French Laboratories Limited Heterocyclic thioureas, isothioureas, guanidines and nitromethylene-amidines
MA19290A1 (fr) * 1980-05-22 1982-04-01 Ciba Geigy Ag Derives du benzole,leur preparaton et leur utilisations therapeutiques .
US4649149A (en) * 1980-05-22 1987-03-10 Ciba-Geigy Corporation Process for the manufacture of novel benzazole derivatives, pharmaceutical preparations containing these derivatives, and their use
US5247085A (en) * 1987-11-30 1993-09-21 Beecham Group P.L.C. Antiviral purine compounds
PT89098B (pt) * 1987-11-30 1993-03-31 Beecham Group Plc Processo para a preparacao de derivados de guanina
US5693515A (en) * 1995-04-28 1997-12-02 Arris Pharmaceutical Corporation Metal complexed serine protease inhibitors
US6255091B1 (en) * 1995-04-28 2001-07-03 Axys Pharmaceuticals, Inc. Potentiating metal mediated serine protease inhibitors with cobalt or zinc ions
DE60006541D1 (de) 1999-06-30 2003-12-18 Merck & Co Inc Src-kinase hemmende verbindungen
US6316444B1 (en) 1999-06-30 2001-11-13 Merck & Co., Inc. SRC kinase inhibitor compounds
WO2001000207A1 (en) 1999-06-30 2001-01-04 Merck & Co., Inc. Src kinase inhibitor compounds
US7405235B2 (en) * 2001-05-04 2008-07-29 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
JP2006513162A (ja) * 2002-11-01 2006-04-20 パラテック ファーマシューティカルズ インコーポレイテッド 転写因子調節化合物およびその使用方法
AU2003286757B2 (en) * 2002-11-01 2009-06-04 Merck Sharp & Dohme Corp. Carbonylamino-benzimidazole derivatives as androgen receptor modulators
AU2005324492B2 (en) 2004-04-23 2012-06-07 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
CA2656157A1 (en) * 2006-06-23 2008-10-30 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
WO2009005551A2 (en) * 2007-03-27 2009-01-08 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
US20090191138A1 (en) * 2008-01-30 2009-07-30 Mediquest Therapeutics, Inc. Novel topical formulations for improving the appearance of nails
AU2009212135B2 (en) 2008-02-07 2014-08-21 Massachusetts Eye & Ear Infirmary Compounds that enhance Atoh-1 expression
US20110059962A1 (en) * 2009-04-22 2011-03-10 Alekshun Michael N Transcription factor modulating compounds and methods of use thereof
US12570638B2 (en) * 2020-05-20 2026-03-10 Sail Biomedicines, Inc. Fused imidazole derivatives as AHR antagonists

Also Published As

Publication number Publication date
CH566344A5 (enExample) 1975-09-15
GB1328321A (en) 1973-08-30
BE763781R (fr) 1971-09-06
CA967962A (en) 1975-05-20
NL7102895A (enExample) 1971-09-07
US3743738A (en) 1973-07-03
AT310738B (de) 1973-10-10
US3646049A (en) 1972-02-29
FR2085671A1 (enExample) 1971-12-31
FR2085671B1 (enExample) 1975-04-18
NL7102896A (enExample) 1971-09-07
GB1317379A (en) 1973-05-16

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