DE2013498A1 - Stabile gefriergetrocknete Wirkstoffpräparate mit einer genau dosierten Menge des Wirkstoffes - Google Patents
Stabile gefriergetrocknete Wirkstoffpräparate mit einer genau dosierten Menge des WirkstoffesInfo
- Publication number
- DE2013498A1 DE2013498A1 DE19702013498 DE2013498A DE2013498A1 DE 2013498 A1 DE2013498 A1 DE 2013498A1 DE 19702013498 DE19702013498 DE 19702013498 DE 2013498 A DE2013498 A DE 2013498A DE 2013498 A1 DE2013498 A1 DE 2013498A1
- Authority
- DE
- Germany
- Prior art keywords
- liquid
- active ingredient
- solution
- drops
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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- B01L3/02—Burettes; Pipettes
- B01L3/0203—Burettes, i.e. for withdrawing and redistributing liquids through different conduits
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25C—PRODUCING, WORKING OR HANDLING ICE
- F25C1/00—Producing ice
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S436/805—Optical property
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/81—Tube, bottle, or dipstick
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/814—Pregnancy
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
- Y10S436/818—Human chorionic gonadotropin
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Clinical Laboratory Science (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Mechanical Engineering (AREA)
- Thermal Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80880369A | 1969-03-20 | 1969-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2013498A1 true DE2013498A1 (de) | 1970-09-24 |
Family
ID=25199790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19702013498 Pending DE2013498A1 (de) | 1969-03-20 | 1970-03-20 | Stabile gefriergetrocknete Wirkstoffpräparate mit einer genau dosierten Menge des Wirkstoffes |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US3655838A (enExample) |
| JP (1) | JPS5334518B1 (enExample) |
| BE (1) | BE747699A (enExample) |
| CH (1) | CH546570A (enExample) |
| DE (1) | DE2013498A1 (enExample) |
| ES (1) | ES377661A1 (enExample) |
| FI (1) | FI52409C (enExample) |
| FR (1) | FR2037234A1 (enExample) |
| GB (1) | GB1304045A (enExample) |
| IL (1) | IL34041A (enExample) |
| NL (1) | NL7003963A (enExample) |
| SE (1) | SE376087B (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3955923A (en) * | 1973-01-31 | 1976-05-11 | Ortho Pharmaceutical Corporation | Serologic reaction method |
| US3995019A (en) * | 1975-03-04 | 1976-11-30 | Baxter Travenol Laboratories, Inc. | Diagnostic reagent system |
| US4003988A (en) * | 1976-06-01 | 1977-01-18 | Warner-Lambert Company | Direct agglutination test for pregnancy |
| JPS5341420A (en) * | 1976-09-29 | 1978-04-14 | Mochida Pharm Co Ltd | Immunochemically measuring methoa of hapten |
| US4323478A (en) * | 1977-01-18 | 1982-04-06 | Baxter Travenol Laboratories, Inc. | Novel particulate compositions |
| US4211015A (en) * | 1978-01-18 | 1980-07-08 | Baxter Travenol Laboratories, Inc. | Method and apparatus for making novel particulate compositions |
| US4320111A (en) * | 1977-06-14 | 1982-03-16 | American Home Products Corporation | Immunologic compositions methods of preparation and use |
| US4184849A (en) * | 1977-12-05 | 1980-01-22 | Technicon Instruments Corporation | Mixed agglutination |
| US4289748A (en) * | 1979-05-31 | 1981-09-15 | United States Of America | Ultrasensitive enzymatic radioimmunoassay method |
| DE2925009A1 (de) * | 1979-06-21 | 1981-01-08 | Basf Ag | Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung |
| US4282002A (en) * | 1979-09-06 | 1981-08-04 | Akzona Incorporated | Sensitized sheep stroma immunoassay for rheumatoid factor |
| US4351158A (en) * | 1980-01-22 | 1982-09-28 | American Home Products Corporation | Method of producing multicomponent lyophilized product |
| FR2476320B1 (fr) * | 1980-02-15 | 1985-10-25 | Guffroy Rene | Nouveau reactif immunologique pour la detection en tubes du facteur rhumatoide dans un echantillon biologique et procede de preparation de ce nouveau reactif |
| US4295280A (en) * | 1980-03-17 | 1981-10-20 | American Home Products Corporation | Method of obtaining a lyophilized product |
| US4447527A (en) * | 1980-09-02 | 1984-05-08 | Syva Company | Single test formulations for enzyme immunoassays and method for preparation |
| CA1164340A (en) * | 1980-09-02 | 1984-03-27 | Alex A. Monte | Single test compositions for immunoassays |
| JPS57149234U (enExample) * | 1981-03-10 | 1982-09-18 | ||
| JPS57183284U (enExample) * | 1981-05-16 | 1982-11-20 | ||
| DE3264450D1 (en) * | 1981-12-11 | 1985-08-01 | Wyeth John & Brother Ltd | Process and apparatus for freezing a liquid medium |
| JPS6183569U (enExample) * | 1984-11-08 | 1986-06-02 | ||
| ATE48036T1 (de) * | 1985-08-19 | 1989-12-15 | Akzo Nv | Geraet zur durchfuehrung einer immunochemischen bestimmung. |
| US4712310A (en) * | 1986-09-15 | 1987-12-15 | E. I. Du Pont De Nemours And Company | Co-spray technique |
| EP0266859A1 (en) * | 1986-10-06 | 1988-05-11 | Taiyo Sanso Co Ltd. | Method and apparatus for producing microfine frozen particles |
| CH674410A5 (enExample) * | 1987-05-25 | 1990-05-31 | Rosenmund Ag | |
| US4988627A (en) * | 1987-12-18 | 1991-01-29 | Eastman Kodak Company | Test device with dried reagent drops on inclined wall |
| GB8802174D0 (en) * | 1988-02-01 | 1988-03-02 | Quadrant Bioresources Ltd | Method of drying macromolecules |
| US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
| US5413732A (en) † | 1991-08-19 | 1995-05-09 | Abaxis, Inc. | Reagent compositions for analytical testing |
| US5776563A (en) | 1991-08-19 | 1998-07-07 | Abaxis, Inc. | Dried chemical compositions |
| IL120202A (en) | 1996-03-07 | 2001-03-19 | Akzo Nobel Nv | Container with freeze-dried vaccine components |
| FR2756196A1 (fr) * | 1996-11-25 | 1998-05-29 | Air Liquide | Procede et dispositif de fabrication de granulats |
| US6165796A (en) * | 1997-11-26 | 2000-12-26 | Beckman Coulter, Inc. | Pipettable ion detector and method |
| US6354091B1 (en) * | 2001-02-01 | 2002-03-12 | Spectral Diagnostics, Inc. | Apparatus and method for the production of frozen beads |
| US6780581B2 (en) | 2001-09-12 | 2004-08-24 | Btf Pty Ltd | Products comprising quantum of bioparticles and method for production thereof |
| AUPR750501A0 (en) * | 2001-09-05 | 2001-09-27 | Gauci, Mark | Products comprising quantum of bioparticles and method for production thereof |
| US6755886B2 (en) * | 2002-04-18 | 2004-06-29 | The Regents Of The University Of California | Method for producing metallic microparticles |
| DE102004007526A1 (de) * | 2004-02-17 | 2005-09-01 | Oetjen, Georg-Wilhelm, Dr. | Verfahren und Einrichtung zur Gefriertrocknung von Produkten |
| GB0522193D0 (en) | 2005-10-31 | 2005-12-07 | Axis Shield Asa | Method |
| EP1870649A1 (en) | 2006-06-20 | 2007-12-26 | Octapharma AG | Lyophilisation targetting defined residual moisture by limited desorption energy levels |
| US20080075777A1 (en) * | 2006-07-31 | 2008-03-27 | Kennedy Michael T | Apparatus and methods for preparing solid particles |
| FR2906688B1 (fr) | 2006-10-09 | 2012-04-20 | Lavisse Isabelle Desjardins | Procede d'obtention d'un produit subissant a la fois une gazeification et une surgelation |
| CN103157400B (zh) * | 2007-06-21 | 2014-12-24 | 简·探针公司 | 用于将容器暴露于多个热区的仪器和方法 |
| CN105944095B (zh) | 2008-03-05 | 2021-04-02 | 赛诺菲巴斯德有限公司 | 一种使含佐剂的疫苗组合物稳定的方法 |
| GB0805296D0 (en) * | 2008-03-20 | 2008-04-30 | Iti Scotland Ltd | Uses of reagents in sample collection and cartridge systems |
| EP2143440A1 (fr) | 2008-07-09 | 2010-01-13 | Sanofi Pasteur | Agent stabilisant et composition vaccinale comprenant un ou plusieurs flavivirus vivants atténués |
| CA2750900C (en) | 2009-01-30 | 2017-03-28 | Gen-Probe Incorporated | Systems and methods for detecting a signal and applying thermal energy to a signal transmission element |
| US20130008191A1 (en) * | 2011-07-07 | 2013-01-10 | Suchak Naresh J | Methods for freezing and thawing proteins |
| JP2014533240A (ja) | 2011-10-31 | 2014-12-11 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | 生物材料の凍結乾燥球形ペレットを調製する方法 |
| JP6855469B2 (ja) | 2015-10-16 | 2021-04-07 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | 消化器標的療法のための処方物を調製するための工程 |
| EP3811007A1 (en) | 2018-06-20 | 2021-04-28 | Gen-Probe Incorporated | Method and apparatus for freezing dispensed droplets of liquid |
| CN109619672B (zh) * | 2019-02-18 | 2021-09-28 | 重庆中烟工业有限责任公司 | 一种烟用胶囊及其制备方法与滤嘴 |
| JP6691256B1 (ja) * | 2019-07-25 | 2020-04-28 | 大阪ガスリキッド株式会社 | 凍結体製造装置 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3236732A (en) * | 1962-01-22 | 1966-02-22 | Edward R Arquilla | Pregnancy test method and immunological indicator therefor |
| US3344617A (en) * | 1965-02-25 | 1967-10-03 | Union Carbide Corp | Apparatus for the preservation of biological substances |
| NL126572C (enExample) * | 1966-03-24 | |||
| US3654090A (en) * | 1968-09-24 | 1972-04-04 | Organon | Method for the determination of antigens and antibodies |
| US3579306A (en) * | 1969-01-22 | 1971-05-18 | Organon | Diagnostic test device |
-
1969
- 1969-03-20 US US808803A patent/US3655838A/en not_active Expired - Lifetime
-
1970
- 1970-03-10 IL IL34041A patent/IL34041A/xx unknown
- 1970-03-18 CH CH408370A patent/CH546570A/xx not_active IP Right Cessation
- 1970-03-18 ES ES377661A patent/ES377661A1/es not_active Expired
- 1970-03-19 NL NL7003963A patent/NL7003963A/xx unknown
- 1970-03-19 SE SE7003700A patent/SE376087B/xx unknown
- 1970-03-19 FI FI700776A patent/FI52409C/fi active
- 1970-03-20 DE DE19702013498 patent/DE2013498A1/de active Pending
- 1970-03-20 BE BE747699D patent/BE747699A/xx not_active IP Right Cessation
- 1970-03-20 JP JP2401770A patent/JPS5334518B1/ja active Pending
- 1970-03-20 GB GB1364970A patent/GB1304045A/en not_active Expired
- 1970-03-20 FR FR7010211A patent/FR2037234A1/fr not_active Withdrawn
-
1971
- 1971-10-04 US US186473A patent/US3862302A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NL7003963A (enExample) | 1970-09-22 |
| JPS5334518B1 (enExample) | 1978-09-21 |
| CH546570A (de) | 1974-03-15 |
| GB1304045A (enExample) | 1973-01-24 |
| FI52409B (enExample) | 1977-05-02 |
| ES377661A1 (es) | 1973-02-01 |
| IL34041A0 (en) | 1970-05-21 |
| BE747699A (fr) | 1970-09-21 |
| SE376087B (enExample) | 1975-05-05 |
| FI52409C (fi) | 1977-08-10 |
| IL34041A (en) | 1973-05-31 |
| US3655838A (en) | 1972-04-11 |
| FR2037234A1 (enExample) | 1970-12-31 |
| US3862302A (en) | 1975-01-21 |
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