DE19917990A1 - Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk - Google Patents

Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk

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Publication number
DE19917990A1
DE19917990A1 DE19917990A DE19917990A DE19917990A1 DE 19917990 A1 DE19917990 A1 DE 19917990A1 DE 19917990 A DE19917990 A DE 19917990A DE 19917990 A DE19917990 A DE 19917990A DE 19917990 A1 DE19917990 A1 DE 19917990A1
Authority
DE
Germany
Prior art keywords
sgk
kinase
cell volume
human kinase
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19917990A
Other languages
German (de)
English (en)
Inventor
Florian Lang
Siegfried Waldegger
Carsten Wagner
Stefan Broeer
Karin Klingel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19917990A priority Critical patent/DE19917990A1/de
Priority to HU0200819A priority patent/HUP0200819A3/hu
Priority to BR0009914-7A priority patent/BR0009914A/pt
Priority to AU42972/00A priority patent/AU779941B2/en
Priority to CA002369078A priority patent/CA2369078A1/en
Priority to CN00807959A priority patent/CN1351496A/zh
Priority to CZ20013778A priority patent/CZ20013778A3/cs
Priority to UA2001117896A priority patent/UA79066C2/uk
Priority to PL352547A priority patent/PL198427B1/pl
Priority to MXPA01010588A priority patent/MXPA01010588A/es
Priority to EP00922655A priority patent/EP1171131A1/de
Priority to PCT/EP2000/003578 priority patent/WO2000062781A1/de
Priority to SK1497-2001A priority patent/SK14972001A3/sk
Priority to RU2001131351/15A priority patent/RU2288718C9/ru
Priority to KR1020017013336A priority patent/KR100718900B1/ko
Priority to JP2000611917A priority patent/JP2002542196A/ja
Publication of DE19917990A1 publication Critical patent/DE19917990A1/de
Priority to NO20015054A priority patent/NO20015054L/no
Priority to ZA200108610A priority patent/ZA200108610B/en
Priority to US10/984,945 priority patent/US20050064501A1/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/005Enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19917990A 1999-04-20 1999-04-20 Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk Ceased DE19917990A1 (de)

Priority Applications (19)

Application Number Priority Date Filing Date Title
DE19917990A DE19917990A1 (de) 1999-04-20 1999-04-20 Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk
MXPA01010588A MXPA01010588A (es) 1999-04-20 2000-04-19 Medicamentos que contienen de la cinasa humana regulada por el volumen celular h-sgk.
EP00922655A EP1171131A1 (de) 1999-04-20 2000-04-19 Arzneimittel enthaltend hemmstoffe der zellvolumenregulierten humanen kinase h-sgk
AU42972/00A AU779941B2 (en) 1999-04-20 2000-04-19 Medicaments containing inhibitors of cell-volume regulated human kinase h-sgk
CA002369078A CA2369078A1 (en) 1999-04-20 2000-04-19 Medicaments containing inhibitors of cell-volume regulated human kinase h-sgk
CN00807959A CN1351496A (zh) 1999-04-20 2000-04-19 包含调节细胞容量的人激酶h-sgk的抑制剂的药物
CZ20013778A CZ20013778A3 (cs) 1999-04-20 2000-04-19 Farmaceutické prostředky obsahující inhibitory buněčným objemem regulované lidské kinasy h-sgk a jejich pouľití
UA2001117896A UA79066C2 (en) 1999-04-20 2000-04-19 Transdominant inhibitory kinase h-sgk in which lysine is substituted in the 127 position by arginine, and its use for preparation the remedy
PL352547A PL198427B1 (pl) 1999-04-20 2000-04-19 Zastosowanie chelerytryny
HU0200819A HUP0200819A3 (en) 1999-04-20 2000-04-19 Medicaments containing inhibitors of cell-volume regulated human kinase h-sgk
BR0009914-7A BR0009914A (pt) 1999-04-20 2000-04-19 Medicamento, e, usos de um inibidor, e de um ativador de quinase h-sgk humana regulada por volume celular
PCT/EP2000/003578 WO2000062781A1 (de) 1999-04-20 2000-04-19 Arzneimittel enthaltend hemmstoffe der zellvolumenregulierten humanen kinase h-sgk
SK1497-2001A SK14972001A3 (sk) 1999-04-20 2000-04-19 Liečivá obsahujúce inhibítory bunkovým objemom regulovanej ľudskej kinázy h-sgk
RU2001131351/15A RU2288718C9 (ru) 1999-04-20 2000-04-19 ЛЕКАРСТВЕННЫЕ СРЕДСТВА, СОДЕРЖАЩИЕ ИНГИБИТОРЫ ЧЕЛОВЕЧЕСКОЙ h-sgk КИНАЗЫ, КОНТРОЛИРУЮЩЕЙ КЛЕТОЧНЫЙ ОБЪЕМ
KR1020017013336A KR100718900B1 (ko) 1999-04-20 2000-04-19 세포 부피 조절된 인간 키나아제 h-sgk의 억제제를 함유하는 의약
JP2000611917A JP2002542196A (ja) 1999-04-20 2000-04-19 細胞容量調節ヒトキナーゼh−sgkのインヒビター含有医薬
NO20015054A NO20015054L (no) 1999-04-20 2001-10-17 Legemidler omfattende inhibitorer av cellevolumregulert human Kinase H-SGK
ZA200108610A ZA200108610B (en) 1999-04-20 2001-10-19 Medicaments contining inhibitors of cell-volume regulated human kinase h-sgk.
US10/984,945 US20050064501A1 (en) 1999-04-20 2004-11-10 Medicaments comprising inhibitors of the cell volume-regulated human kinase h-sgk

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19917990A DE19917990A1 (de) 1999-04-20 1999-04-20 Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk

Publications (1)

Publication Number Publication Date
DE19917990A1 true DE19917990A1 (de) 2000-11-02

Family

ID=7905297

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19917990A Ceased DE19917990A1 (de) 1999-04-20 1999-04-20 Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk

Country Status (18)

Country Link
EP (1) EP1171131A1 (https=)
JP (1) JP2002542196A (https=)
KR (1) KR100718900B1 (https=)
CN (1) CN1351496A (https=)
AU (1) AU779941B2 (https=)
BR (1) BR0009914A (https=)
CA (1) CA2369078A1 (https=)
CZ (1) CZ20013778A3 (https=)
DE (1) DE19917990A1 (https=)
HU (1) HUP0200819A3 (https=)
MX (1) MXPA01010588A (https=)
NO (1) NO20015054L (https=)
PL (1) PL198427B1 (https=)
RU (1) RU2288718C9 (https=)
SK (1) SK14972001A3 (https=)
UA (1) UA79066C2 (https=)
WO (1) WO2000062781A1 (https=)
ZA (1) ZA200108610B (https=)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002017893A3 (de) * 2000-08-28 2003-01-23 Florian Lang Sgk2 und sgk3 als diagnostische und therapeutische targets
DE10149393A1 (de) * 2001-09-28 2003-04-24 Florian Lang sgk1 als diagnostisches und therapeutisches target
WO2004079003A1 (de) * 2003-03-03 2004-09-16 Florian Lang Sgk1 als diagnostisches und therapeutisches target
WO2004069258A3 (de) * 2003-02-07 2005-02-24 Florian Lang Verwendung der sgk-genfamilie zur diagnose und zur therapie von katarakt und glaukom
WO2006010628A1 (en) * 2004-07-29 2006-02-02 Creabilis Therapeutics S.P.A. Use of k-252a and kinase inhibitors for the prevention or treatment of hmgb1-associated pathologies
WO2005118832A3 (en) * 2004-06-01 2006-04-13 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with serum/glucocorticoid regulated kinase-like protein (sgkl)
EP2014651A1 (en) * 2007-07-12 2009-01-14 Exonhit Therapeutics SA Compounds and methods for modulating Rho GTPases
DE102008010361A1 (de) 2008-02-18 2009-08-20 Merck Patent Gmbh sgk1-Inhibitoren zur Prophylaxe und/oder Therapie von viralen Erkrankungen und/oder Karzinomen
DE102008010363A1 (de) 2008-02-18 2009-08-20 Lang, Florian, Prof. Dr.med. Sgk1 als therapeutisches und diagnostisches Target für karzinomatöse Erkrankungen
DE102008010362A1 (de) 2008-02-18 2009-08-20 Florian Prof. Dr. Lang Sgk1 als therapeutisches und diagnostisches Target für virale Erkrankungen
DE102008029072A1 (de) * 2008-06-10 2009-12-17 Lang, Florian, Prof. Dr.med. Sgk3 als therapeutisches und diagnostisches Target für Alterserkrankungen

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DE10113876A1 (de) * 2001-03-21 2002-09-26 Eberhard Karls Uni Medizinisch Quantitative diagnostische Analyse der Hypertonie
DE60233398D1 (de) * 2001-04-27 2009-10-01 Cold Spring Harbor Lab Linderung der gedächtnisdefizite und gedächtniskomponenten von psychiatrischen funktionsstörungen durch veränderung der atypischen pkm-aktivität
DE10225844A1 (de) * 2002-06-04 2003-12-18 Lang Florian sgk und nedd als diagnostische und therapeutische targets
WO2004084889A1 (en) * 2003-03-28 2004-10-07 Pfizer Inc. Use of protein kinase c inhibitor for suppressing sustained slow postsynaptic excitation (sspe) of enteric neurons
DE10346913A1 (de) 2003-10-09 2005-05-04 Merck Patent Gmbh Acylhydrazonderivate
WO2005084702A1 (ja) * 2004-03-02 2005-09-15 Hokkaido Technology Licensing Office Co., Ltd. 臓器線維症予防・治療剤
WO2005094796A2 (en) * 2004-03-11 2005-10-13 Merck Patent Gmbh Methods for interfering with fibrosis
AU2005229496A1 (en) * 2004-03-11 2005-10-13 Merck Patent Gmbh Methods for modulating glutamate receptors for treating neuropsychiatric disorders comprising the use of modulators of serum and glucocorticoid inducible kinases
WO2005106491A2 (en) * 2004-04-30 2005-11-10 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with serum/glucocorticoid regulated kinase 1 (sgk1)
DE102004030987A1 (de) * 2004-06-26 2006-01-12 Merck Patent Gmbh Ortho-substituierte (3-Hydroxyphenyl)-essigsäure-benzyliden-hydrazide
DE102005001053A1 (de) * 2005-01-07 2006-07-20 Merck Patent Gmbh Quadratsäurederivate
DE102005015255A1 (de) * 2005-04-04 2006-10-05 Merck Patent Gmbh Acylhydrazide
DE102005035742A1 (de) * 2005-07-29 2007-02-01 Merck Patent Gmbh Quadratsäurederivate II
DE102005039541A1 (de) * 2005-08-22 2007-03-22 Merck Patent Gmbh 3-Oxo-indazol-quadratsäurederivate
DE102007002717A1 (de) 2007-01-18 2008-07-24 Merck Patent Gmbh Heterocyclische Indazolderivate
DE102007022565A1 (de) 2007-05-14 2008-11-20 Merck Patent Gmbh Heterocyclische Indazolderivate
DE102008038222A1 (de) 2008-08-18 2010-02-25 Merck Patent Gmbh Indazol-5-carbonsäurehydrazid-derivate
DE102008038221A1 (de) 2008-08-18 2010-02-25 Merck Patent Gmbh 7-Azaindolderivate
DE102008038220A1 (de) 2008-08-18 2010-02-25 Merck Patent Gmbh Oxadiazolderivate
DE102008059133A1 (de) 2008-11-26 2010-05-27 Merck Patent Gmbh Difluorphenyl-diacylhydrazid-derivate
EP2637650A2 (en) 2010-11-10 2013-09-18 National Jewish Health Methods to test allergic conditions
CN107875153A (zh) * 2017-11-16 2018-04-06 上海壹志医药科技有限公司 去甲白屈菜红碱的药物用途

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US5242397A (en) * 1989-06-20 1993-09-07 Cedars-Sinai Medical Center Catheter device and method of use for intramural delivery of protein kinase C and tyrosine protein kinase inhibitors to prevent restenosis after balloon angioplasty
US5137912A (en) * 1991-01-28 1992-08-11 National Science Council Of Republic Of China Chelerythrine inhibits platelet aggregation--a potential anti-aggregation drug
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
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ES2170390T3 (es) * 1996-05-30 2002-08-01 Aventis Pharma Inc Fluorenonas alquiloxiamino-substituidas y su uso como inhibidores de la proteina kinasa-c.
EP0887081B1 (en) * 1997-06-27 2003-04-23 Smithkline Beecham Corporation Human serum glucocorticoid regulated kinase, a target for chronic renal disease and diabetic nephropathy
EP0889127A1 (en) * 1997-07-01 1999-01-07 Smithkline Beecham Corporation Serine/threonine protein kinase (H-SGK2)
CO4940430A1 (es) * 1997-07-07 2000-07-24 Novartis Ag Compuestos policiclicos que contienen estaurosporina hidrogenada con propiedades farmacologicas convenientes y un efecto inhibidor sobre el crecimiento de las celulas tumorales

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002017893A3 (de) * 2000-08-28 2003-01-23 Florian Lang Sgk2 und sgk3 als diagnostische und therapeutische targets
DE10149393A1 (de) * 2001-09-28 2003-04-24 Florian Lang sgk1 als diagnostisches und therapeutisches target
WO2004069258A3 (de) * 2003-02-07 2005-02-24 Florian Lang Verwendung der sgk-genfamilie zur diagnose und zur therapie von katarakt und glaukom
KR101032281B1 (ko) * 2003-03-03 2011-05-06 플로리안 랑 진단 및 치료 표적으로서의 sgk1
WO2004079003A1 (de) * 2003-03-03 2004-09-16 Florian Lang Sgk1 als diagnostisches und therapeutisches target
WO2005118832A3 (en) * 2004-06-01 2006-04-13 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with serum/glucocorticoid regulated kinase-like protein (sgkl)
WO2006010628A1 (en) * 2004-07-29 2006-02-02 Creabilis Therapeutics S.P.A. Use of k-252a and kinase inhibitors for the prevention or treatment of hmgb1-associated pathologies
EP2014651A1 (en) * 2007-07-12 2009-01-14 Exonhit Therapeutics SA Compounds and methods for modulating Rho GTPases
DE102008010363A1 (de) 2008-02-18 2009-08-20 Lang, Florian, Prof. Dr.med. Sgk1 als therapeutisches und diagnostisches Target für karzinomatöse Erkrankungen
DE102008010362A1 (de) 2008-02-18 2009-08-20 Florian Prof. Dr. Lang Sgk1 als therapeutisches und diagnostisches Target für virale Erkrankungen
WO2009103493A1 (de) * 2008-02-18 2009-08-27 Florian Lang Sgk1 als therapeutisches und diagnostisches target für virale erkrankungen
DE102008010361A1 (de) 2008-02-18 2009-08-20 Merck Patent Gmbh sgk1-Inhibitoren zur Prophylaxe und/oder Therapie von viralen Erkrankungen und/oder Karzinomen
DE102008029072A1 (de) * 2008-06-10 2009-12-17 Lang, Florian, Prof. Dr.med. Sgk3 als therapeutisches und diagnostisches Target für Alterserkrankungen

Also Published As

Publication number Publication date
EP1171131A1 (de) 2002-01-16
PL352547A1 (en) 2003-08-25
KR100718900B1 (ko) 2007-05-17
PL198427B1 (pl) 2008-06-30
NO20015054D0 (no) 2001-10-17
CN1351496A (zh) 2002-05-29
NO20015054L (no) 2001-12-14
MXPA01010588A (es) 2004-09-06
CA2369078A1 (en) 2000-10-26
JP2002542196A (ja) 2002-12-10
AU4297200A (en) 2000-11-02
AU779941B2 (en) 2005-02-17
HUP0200819A2 (hu) 2002-07-29
HUP0200819A3 (en) 2009-08-28
RU2288718C9 (ru) 2008-04-27
SK14972001A3 (sk) 2002-06-04
CZ20013778A3 (cs) 2002-06-12
BR0009914A (pt) 2002-01-08
RU2288718C2 (ru) 2006-12-10
ZA200108610B (en) 2002-01-02
KR20020012172A (ko) 2002-02-15
UA79066C2 (en) 2007-05-25
WO2000062781A1 (de) 2000-10-26

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