DE19802708A1 - Verwendung von hydroxypyridon-haltigen Puderzubereitungen zur Behandlung von Unterschenkel- und Druckgeschwüren - Google Patents

Verwendung von hydroxypyridon-haltigen Puderzubereitungen zur Behandlung von Unterschenkel- und Druckgeschwüren

Info

Publication number
DE19802708A1
DE19802708A1 DE19802708A DE19802708A DE19802708A1 DE 19802708 A1 DE19802708 A1 DE 19802708A1 DE 19802708 A DE19802708 A DE 19802708A DE 19802708 A DE19802708 A DE 19802708A DE 19802708 A1 DE19802708 A1 DE 19802708A1
Authority
DE
Germany
Prior art keywords
atoms
hydroxy
pyridone
formula
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19802708A
Other languages
German (de)
English (en)
Inventor
Manfred Dr Bohn
Karl Theodor Dr Kraemer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Hoechst Marion Roussel Deutschland GmbH
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Deutschland GmbH, Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Deutschland GmbH
Priority to DE19802708A priority Critical patent/DE19802708A1/de
Priority to YUP-437/00A priority patent/RS50903B/sr
Priority to CN99802327A priority patent/CN1128619C/zh
Priority to PCT/EP1999/000105 priority patent/WO1999037300A1/de
Priority to JP2000528282A priority patent/JP5127091B2/ja
Priority to TR2000/02118T priority patent/TR200002118T2/xx
Priority to PT99902528T priority patent/PT1049468E/pt
Priority to SI9930962T priority patent/SI1049468T1/sl
Priority to CZ20002664A priority patent/CZ295316B6/cs
Priority to BR9907734-5A priority patent/BR9907734A/pt
Priority to ES99902528T priority patent/ES2285829T3/es
Priority to HU0200851A priority patent/HU228824B1/hu
Priority to RU2000122313/14A priority patent/RU2212239C2/ru
Priority to EP99902528A priority patent/EP1049468B1/de
Priority to DE59914312T priority patent/DE59914312D1/de
Priority to KR1020007008050A priority patent/KR100597332B1/ko
Priority to MEP-559/08A priority patent/MEP55908A/xx
Priority to HR20000496A priority patent/HRP20000496A2/hr
Priority to SK1089-2000A priority patent/SK285350B6/sk
Priority to US09/600,903 priority patent/US6534528B1/en
Priority to HK01104925.1A priority patent/HK1034447B/xx
Priority to DK99902528T priority patent/DK1049468T3/da
Priority to PL342055A priority patent/PL192550B1/pl
Priority to AT99902528T priority patent/ATE360418T1/de
Priority to NZ505898A priority patent/NZ505898A/en
Priority to AU22787/99A priority patent/AU752406B2/en
Priority to CA002319359A priority patent/CA2319359C/en
Priority to IL13745399A priority patent/IL137453A/xx
Priority to ARP990100243A priority patent/AR016445A1/es
Publication of DE19802708A1 publication Critical patent/DE19802708A1/de
Priority to CY20071100855T priority patent/CY1106684T1/el
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19802708A 1998-01-24 1998-01-24 Verwendung von hydroxypyridon-haltigen Puderzubereitungen zur Behandlung von Unterschenkel- und Druckgeschwüren Withdrawn DE19802708A1 (de)

Priority Applications (30)

Application Number Priority Date Filing Date Title
DE19802708A DE19802708A1 (de) 1998-01-24 1998-01-24 Verwendung von hydroxypyridon-haltigen Puderzubereitungen zur Behandlung von Unterschenkel- und Druckgeschwüren
MEP-559/08A MEP55908A (en) 1998-01-24 1999-01-11 Utilzation of powder preparations containig hydroxypvridones for treating leg ulcers and decubitus ulcers
KR1020007008050A KR100597332B1 (ko) 1998-01-24 1999-01-11 하이드록시피리돈을 함유하는 하지 괴저 및 욕창 궤양 치료용 약제학적 분말 조성물
PCT/EP1999/000105 WO1999037300A1 (de) 1998-01-24 1999-01-11 Verwendung von hydroxypyridon-haltigen puderzubereitungen zur behandlung von unterschenkel- und druckgeschwüren
JP2000528282A JP5127091B2 (ja) 1998-01-24 1999-01-11 下腿潰瘍および圧迫性潰瘍の治療のためのヒドロキシピリドン含有粉末製剤の使用
TR2000/02118T TR200002118T2 (tr) 1998-01-24 1999-01-11 Baldırdaki ülserlerin ve dekubitik ülserlerin tedavisinde pudra müstahzarlarının kullanılması.
PT99902528T PT1049468E (pt) 1998-01-24 1999-01-11 Utilização de preparações em pó contendo hidroxipiridona para o tratamento de úlceras da perna e úlceras de pressão
SI9930962T SI1049468T1 (sl) 1998-01-24 1999-01-11 Uporaba praškastih pripravkov, ki vsebujejo hidroksipiridon, za zdravljenje golenskih razjed in preležanin
CZ20002664A CZ295316B6 (cs) 1998-01-24 1999-01-11 Léčivo k léčbě bércových vředů a proleženin
BR9907734-5A BR9907734A (pt) 1998-01-24 1999-01-11 Emprego de preparados em pó contendo hidroxipiridona para o tratamento de tumores da perna e de pressão
ES99902528T ES2285829T3 (es) 1998-01-24 1999-01-11 Uso de preparados en polvo que contienen hidroxipiridona para el tratamiento de ulceras de los miembros inferiores y ulceras por presion.
HU0200851A HU228824B1 (en) 1998-01-24 1999-01-11 Utilization of powder preparations containing hydroxypyridones for treating leg ulcers and decubitus ulcers
RU2000122313/14A RU2212239C2 (ru) 1998-01-24 1999-01-11 Применение гидроксипиридонсодержащей препаративной формы в виде присыпки для лечения варикозной язвы и пролежней
EP99902528A EP1049468B1 (de) 1998-01-24 1999-01-11 Verwendung von hydroxypyridon-haltigen puderzubereitungen zur behandlung von unterschenkel- und druckgeschwüren
DE59914312T DE59914312D1 (de) 1998-01-24 1999-01-11 Verwendung von hydroxypyridon-haltigen puderzubereitungen zur behandlung von unterschenkel- und druckgeschwüren
YUP-437/00A RS50903B (sr) 1998-01-24 1999-01-11 Primena preparata u obliku pudera koji sadrži hidroksipiridon za tretman ulkusa na potkolenici ili dekubitusnog ulcera
US09/600,903 US6534528B1 (en) 1998-01-24 1999-01-11 Utilization of powder preparations containing hydroxypyridones for treating leg ulcers and decubitus ulcers
CN99802327A CN1128619C (zh) 1998-01-24 1999-01-11 含有羟基吡啶酮的粉末制剂用于治疗腿部溃疡和压迫溃疡的用途
SK1089-2000A SK285350B6 (sk) 1998-01-24 1999-01-11 Použitie prášku a najmenej jedného 1-hydroxy-2-pyridónu
HR20000496A HRP20000496A2 (en) 1998-01-24 1999-01-11 Utilization of powder preparations containing hydroxypyridones for treating leg ulcers and decubitus ulcers
HK01104925.1A HK1034447B (en) 1998-01-24 1999-01-11 Utilization of powder preparations containing hydroxypyridones for treating leg ulcers and decubitus ulcers
DK99902528T DK1049468T3 (da) 1998-01-24 1999-01-11 Anvendelse af hydroxypyridonholdige pudderpræparater til behandling af skinnebens- og tryksår
PL342055A PL192550B1 (pl) 1998-01-24 1999-01-11 Zastosowanie zasypki i związku hydroksypirydonowego
AT99902528T ATE360418T1 (de) 1998-01-24 1999-01-11 Verwendung von hydroxypyridon-haltigen puderzubereitungen zur behandlung von unterschenkel- und druckgeschwüren
NZ505898A NZ505898A (en) 1998-01-24 1999-01-11 Powder preparations containing hydroxypyridones; useful for treating leg ulcers and/or decubitus ulcers
AU22787/99A AU752406B2 (en) 1998-01-24 1999-01-11 Utilization of powder preparations containing hydroxypyridones for treating leg ulcers and decubitus ulcers
CA002319359A CA2319359C (en) 1998-01-24 1999-01-11 Utilization of powder preparations containing hydroxypyridones for treating leg ulcers and decubitus ulcers
IL13745399A IL137453A (en) 1998-01-24 1999-01-11 Utilization of powder preparations containing hydroxypyridones for the production of a medicament for the treatment of leg ulcers and decubitus ulcers
ARP990100243A AR016445A1 (es) 1998-01-24 1999-01-21 Procedimiento de utilizacion de preparaciones en polvo que contienen 1-hidroxi-2-piridona para la preparacion de un medicamento para el tratamiento de ulceras en la pierna y ulceras de presion
CY20071100855T CY1106684T1 (el) 1998-01-24 2007-06-28 Χρησιμοποιηση σκευασματων πουδρας που περιεχουν υδροξυπυριδονη για την αγωγη εξελκωσεων κνημης και εξελκωσεων λογω κατακλισης

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19802708A DE19802708A1 (de) 1998-01-24 1998-01-24 Verwendung von hydroxypyridon-haltigen Puderzubereitungen zur Behandlung von Unterschenkel- und Druckgeschwüren

Publications (1)

Publication Number Publication Date
DE19802708A1 true DE19802708A1 (de) 1999-07-29

Family

ID=7855595

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19802708A Withdrawn DE19802708A1 (de) 1998-01-24 1998-01-24 Verwendung von hydroxypyridon-haltigen Puderzubereitungen zur Behandlung von Unterschenkel- und Druckgeschwüren
DE59914312T Expired - Lifetime DE59914312D1 (de) 1998-01-24 1999-01-11 Verwendung von hydroxypyridon-haltigen puderzubereitungen zur behandlung von unterschenkel- und druckgeschwüren

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59914312T Expired - Lifetime DE59914312D1 (de) 1998-01-24 1999-01-11 Verwendung von hydroxypyridon-haltigen puderzubereitungen zur behandlung von unterschenkel- und druckgeschwüren

Country Status (27)

Country Link
US (1) US6534528B1 (https=)
EP (1) EP1049468B1 (https=)
JP (1) JP5127091B2 (https=)
KR (1) KR100597332B1 (https=)
CN (1) CN1128619C (https=)
AR (1) AR016445A1 (https=)
AT (1) ATE360418T1 (https=)
AU (1) AU752406B2 (https=)
BR (1) BR9907734A (https=)
CA (1) CA2319359C (https=)
CY (1) CY1106684T1 (https=)
DE (2) DE19802708A1 (https=)
DK (1) DK1049468T3 (https=)
ES (1) ES2285829T3 (https=)
HR (1) HRP20000496A2 (https=)
HU (1) HU228824B1 (https=)
IL (1) IL137453A (https=)
ME (1) MEP55908A (https=)
NZ (1) NZ505898A (https=)
PL (1) PL192550B1 (https=)
PT (1) PT1049468E (https=)
RS (1) RS50903B (https=)
RU (1) RU2212239C2 (https=)
SI (1) SI1049468T1 (https=)
SK (1) SK285350B6 (https=)
TR (1) TR200002118T2 (https=)
WO (1) WO1999037300A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001122804A (ja) * 1999-10-28 2001-05-08 Sato Pharmaceutical Co Ltd リン酸コーンスターチ配合外用医薬組成物
EP1354586A1 (en) * 2002-04-20 2003-10-22 Aventis Pharma Deutschland GmbH The use of hydroxpyridone-derivatives in wound healing
US20060257439A1 (en) * 2005-03-29 2006-11-16 Sabnis Ram W Cleansing compositions with color changing indicator
RU2326665C1 (ru) * 2007-04-03 2008-06-20 Марвел ЛайфСайнсез Лимитед, Великобритания Средство, обладающее противогипоксическим, противоинсультным, улучшающим память действием
MX2013001095A (es) * 2010-07-27 2013-03-12 Clariant Finance Bvi Ltd Composiciones que comprenden peroxido de hidrogeno o sustancias donadoras de peroxido de hidrogeno.
CN103118973B (zh) * 2010-07-27 2016-03-23 科莱恩金融(Bvi)有限公司 羟基吡啶酮或其盐用于稳定化过氧化氢或释放过氧化氢的物质的用途
RS61907B1 (sr) 2015-04-06 2021-06-30 Subdomain Llc Polipeptidi koji sadrže de novo vezujući domen i njihova primena

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2540218A (en) 1947-08-25 1951-02-06 Squibb & Sons Inc 2-hydroxy-pyridine-n-oxide and process for preparing same
ES2041656T3 (es) 1986-04-18 1993-12-01 Hoechst Aktiengesellschaft Procedimiento para preparar 1-hidroxi-2-piridonas.
JPS63264504A (ja) * 1987-04-17 1988-11-01 Shinto Paint Co Ltd 工業用防カビ組成物
US4956184A (en) * 1988-05-06 1990-09-11 Alcide Corporation Topical treatment of genital herpes lesions
CA2046801C (en) * 1990-08-07 2002-02-26 Peter D. Davis Substituted pyrroles
DE4333893A1 (de) * 1993-10-05 1995-04-06 Hoechst Ag Kosmetische Zubereitungen
ES2176513T3 (es) * 1995-12-04 2002-12-01 Aventis Pharma Gmbh Empleo de 1-hidroxi-2-piridonas para el tratamiento de afecciones de las mucosas de dificil terapia.

Also Published As

Publication number Publication date
AU2278799A (en) 1999-08-09
IL137453A0 (en) 2001-07-24
CA2319359C (en) 2008-03-18
PL342055A1 (en) 2001-05-21
YU43700A (sh) 2003-08-29
DK1049468T3 (da) 2007-07-30
CY1106684T1 (el) 2012-05-23
DE59914312D1 (de) 2007-06-06
RS50903B (sr) 2010-08-31
ME00390B (me) 2011-05-10
WO1999037300A1 (de) 1999-07-29
SK285350B6 (sk) 2006-11-03
PT1049468E (pt) 2007-05-31
JP5127091B2 (ja) 2013-01-23
US6534528B1 (en) 2003-03-18
CN1128619C (zh) 2003-11-26
HUP0200851A1 (hu) 2002-07-29
RU2212239C2 (ru) 2003-09-20
JP2002501020A (ja) 2002-01-15
AU752406B2 (en) 2002-09-19
EP1049468B1 (de) 2007-04-25
KR100597332B1 (ko) 2006-07-10
TR200002118T2 (tr) 2000-12-21
KR20010034325A (ko) 2001-04-25
ES2285829T3 (es) 2007-11-16
CA2319359A1 (en) 1999-07-29
IL137453A (en) 2005-11-20
HRP20000496A2 (en) 2000-12-31
HU228824B1 (en) 2013-05-28
BR9907734A (pt) 2000-10-17
HK1034447A1 (en) 2001-10-26
SI1049468T1 (sl) 2007-08-31
SK10892000A3 (sk) 2000-12-11
MEP55908A (en) 2011-05-10
PL192550B1 (pl) 2006-11-30
CN1288380A (zh) 2001-03-21
NZ505898A (en) 2002-06-28
EP1049468A1 (de) 2000-11-08
AR016445A1 (es) 2001-07-04
ATE360418T1 (de) 2007-05-15
HUP0200851A3 (en) 2003-05-28

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH, 65929 FRANKFURT,

8141 Disposal/no request for examination