DE19702907A1 - Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren - Google Patents

Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren

Info

Publication number
DE19702907A1
DE19702907A1 DE19702907A DE19702907A DE19702907A1 DE 19702907 A1 DE19702907 A1 DE 19702907A1 DE 19702907 A DE19702907 A DE 19702907A DE 19702907 A DE19702907 A DE 19702907A DE 19702907 A1 DE19702907 A1 DE 19702907A1
Authority
DE
Germany
Prior art keywords
vessel
sample
nucleic acids
nucleic acid
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19702907A
Other languages
German (de)
English (en)
Inventor
Thomas Dipl Chem Dr Walter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE19702907A priority Critical patent/DE19702907A1/de
Priority to AU62132/98A priority patent/AU6213298A/en
Priority to US09/355,365 priority patent/US6720417B1/en
Priority to JP53160798A priority patent/JP2001511644A/ja
Priority to PCT/EP1998/000408 priority patent/WO1998032877A1/de
Priority to EP98904143A priority patent/EP0964934A1/de
Publication of DE19702907A1 publication Critical patent/DE19702907A1/de
Priority to US10/786,835 priority patent/US20040166524A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/56—Labware specially adapted for transferring fluids
    • B01L3/563—Joints or fittings; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/56—Labware specially adapted for transferring fluids
    • B01L3/563—Joints or fittings; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors
    • B01L3/5635—Joints or fittings; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors connecting two containers face to face, e.g. comprising a filter
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE19702907A 1997-01-28 1997-01-28 Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren Withdrawn DE19702907A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE19702907A DE19702907A1 (de) 1997-01-28 1997-01-28 Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren
AU62132/98A AU6213298A (en) 1997-01-28 1998-01-26 Method and device for refining nucleic acids
US09/355,365 US6720417B1 (en) 1997-01-28 1998-01-26 Method and device for refining nucleic acids
JP53160798A JP2001511644A (ja) 1997-01-28 1998-01-26 核酸を精製するための方法および装置
PCT/EP1998/000408 WO1998032877A1 (de) 1997-01-28 1998-01-26 Verfahren und vorrichtung zur reinigung von nukleinsäuren
EP98904143A EP0964934A1 (de) 1997-01-28 1998-01-26 Verfahren und vorrichtung zur reinigung von nukleinsäuren
US10/786,835 US20040166524A1 (en) 1997-01-28 2004-02-25 Method and device for purifying nucleic acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702907A DE19702907A1 (de) 1997-01-28 1997-01-28 Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren

Publications (1)

Publication Number Publication Date
DE19702907A1 true DE19702907A1 (de) 1998-07-30

Family

ID=7818496

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19702907A Withdrawn DE19702907A1 (de) 1997-01-28 1997-01-28 Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren

Country Status (6)

Country Link
US (2) US6720417B1 (https=)
EP (1) EP0964934A1 (https=)
JP (1) JP2001511644A (https=)
AU (1) AU6213298A (https=)
DE (1) DE19702907A1 (https=)
WO (1) WO1998032877A1 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000050870A1 (en) * 1999-02-26 2000-08-31 Mosaic Technologies Biochemical purification devices with immobilized capture probes and their uses
DE10006662A1 (de) * 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
US6720417B1 (en) * 1997-01-28 2004-04-13 Roche Diagnostics Gmbh Method and device for refining nucleic acids
DE102004058828A1 (de) * 2004-10-28 2006-06-14 Directif Gmbh Vorrichtung und Verfahren zur parallelen Aufbereitung von Biopolymeren
EP2071037A1 (de) * 1998-08-12 2009-06-17 PreAnalytiX GmbH Gefäß zur Entnahme von Blut

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19746874A1 (de) * 1997-10-23 1999-04-29 Qiagen Gmbh Verfahren zur Isolierung und Reinigung von Nukleinsäuren an hydrophoben Oberflächen - insbesondere unter Verwendung hydrophober Membranen
SE9904539D0 (sv) * 1999-12-10 1999-12-10 Alphahelix Ab Method and device for the handling of samples and reagents
WO2003019131A2 (de) * 2001-08-29 2003-03-06 Hexal Pharma Gmbh Verfahren und vorrichtung zur vorbereitung einer biologischen urprobe für die bestimmung zumindest einer darin enthaltenen komponente
AU2003214708A1 (en) 2003-03-14 2004-09-30 Roque Humberto Ferreyro Irigoyen Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
US7267950B2 (en) * 2003-05-01 2007-09-11 Veridex, Lcc Rapid extraction of RNA from cells and tissues
US8415407B2 (en) 2004-03-21 2013-04-09 Depuy Spine, Inc. Methods, materials, and apparatus for treating bone and other tissue
WO2006011152A2 (en) 2004-06-17 2006-02-02 Disc-O-Tech Medical Technologies, Ltd. Methods for treating bone and other tissue
WO2005030034A2 (en) 2003-09-26 2005-04-07 Depuy Spine, Inc. Device for delivering viscous material
US7897378B2 (en) 2004-03-18 2011-03-01 Roche Molecular Systems, Inc. Method and device for purifying nucleic acids
US20060166223A1 (en) * 2005-01-26 2006-07-27 Reed Michael W DNA purification and analysis on nanoengineered surfaces
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
US8163535B2 (en) * 2006-06-26 2012-04-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
EP2041318A2 (en) 2006-06-26 2009-04-01 Blood Cell Storage, Inc. Device and method for extraction and analysis of nucleic acids from biological samples
KR100805449B1 (ko) 2006-08-18 2008-02-20 배정훈 비석분말을 분자체로 이용하여 아가로스겔에서 dna를정제하는 방법
CA2663447A1 (en) 2006-09-14 2008-03-20 Depuy Spine, Inc. Polymeric bone cement and methods of use thereof
CA2665995C (en) * 2006-10-19 2011-11-29 Oren Globerman Fluid delivery system
US20100028896A1 (en) 2006-12-19 2010-02-04 Konica Minolta Medical & Graphic, Inc. Rotary extraction container and method of identifying cell species, method of detecting gene, and automatic nucleic acid extractor using the same
US8158009B2 (en) * 2007-05-23 2012-04-17 Roush Life Sciences, Llc Methods and apparatus for foam control in a vacuum filtration system
US8231012B2 (en) * 2007-07-26 2012-07-31 Roush Life Sciences, Llc Filtrate storage system
US8157104B2 (en) 2007-07-26 2012-04-17 Roush Life Sciences, Llc Apparatus for supporting a vacuum filtration device
US20090048438A1 (en) * 2007-08-13 2009-02-19 Taigen Bioscience Corporation. Method for washing a column and method for extracting membrane-bound target molecules
EP2055385B1 (en) 2007-10-31 2010-05-26 Roche Diagnostics GmbH Method and device for purifying nucleic acids
CN102264899A (zh) * 2008-11-04 2011-11-30 血细胞保存公司 弯曲的玻璃表面上的核酸提取
WO2012159063A2 (en) 2011-05-19 2012-11-22 Blood Cell Strorage, Inc. Gravity flow fluidic device for nucleic acid extraction
RU2654666C2 (ru) 2013-05-24 2018-05-21 Оккам Байолэбс, Инк. Система и способ сбора образца нуклеиновой кислоты
US10287570B2 (en) 2014-11-21 2019-05-14 Occam Biolabs, Inc. System and method for collecting a sample of nucleic acid
KR102638609B1 (ko) * 2017-07-27 2024-02-19 바이오메리욱스, 인코포레이티드. 격리 튜브

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
WO1991007648A1 (en) * 1989-11-08 1991-05-30 Fmc Corporation Combined centrifuge tube and porous selection means for separation and recovery of biological materials
US5438128A (en) 1992-02-07 1995-08-01 Millipore Corporation Method for rapid purifiction of nucleic acids using layered ion-exchange membranes
AU689815B2 (en) 1993-08-30 1998-04-09 Promega Corporation Nucleic acid purification compositions and methods
AU2201295A (en) * 1994-04-08 1995-10-30 Amicon, Inc. Method and apparatus for isolation and purification of biologically active complexes
JPH10504834A (ja) * 1994-08-29 1998-05-12 アクゾ・ノベル・エヌ・ベー 核酸などの生物材料の単離に使用する装置
DE59609585D1 (de) * 1995-04-01 2002-10-02 Roche Diagnostics Gmbh Verfahren zur Bindung eines biologischen Materials
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren
US5733449A (en) 1995-12-08 1998-03-31 Orbital Biosciences, Llc Microconcentrator device
DE19702907A1 (de) * 1997-01-28 1998-07-30 Boehringer Mannheim Gmbh Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren
DE19725190A1 (de) * 1997-06-14 1998-12-17 Innova Gmbh Vorrichtungen mit integrierten Elektroden aus elektrisch leitfähigen Kunststoffen
JP2001516731A (ja) * 1997-09-17 2001-10-02 ジエントラ・システムズ・インコーポレーテツド 核酸を単離するための装置および方法

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6720417B1 (en) * 1997-01-28 2004-04-13 Roche Diagnostics Gmbh Method and device for refining nucleic acids
EP2071037A1 (de) * 1998-08-12 2009-06-17 PreAnalytiX GmbH Gefäß zur Entnahme von Blut
EP2206792A1 (de) * 1998-08-12 2010-07-14 PreAnalytiX GmbH Gefäß zur Entnahme von Blut
WO2000050870A1 (en) * 1999-02-26 2000-08-31 Mosaic Technologies Biochemical purification devices with immobilized capture probes and their uses
DE10006662A1 (de) * 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
WO2001060517A2 (de) 2000-02-15 2001-08-23 Antigene Biotech Gmbh Gefäss zur nukleinsäureanalytik
WO2001060517A3 (de) * 2000-02-15 2002-08-22 Antigen Produktions Gmbh Gefäss zur nukleinsäureanalytik
AU2001235479B2 (en) * 2000-02-15 2004-10-14 Preanalytix Gmbh Container for nucleic acid analysis
EP2189220A1 (de) * 2000-02-15 2010-05-26 PreAnalytiX GmbH Gefäss zur Nukleinsäureanalytik
EP2189220B1 (de) 2000-02-15 2016-06-08 PreAnalytiX GmbH Verfahren zur Nukleinsäureanalytik
DE102004058828A1 (de) * 2004-10-28 2006-06-14 Directif Gmbh Vorrichtung und Verfahren zur parallelen Aufbereitung von Biopolymeren
DE102004058828B4 (de) * 2004-10-28 2010-08-19 Progen Biotechnik Gmbh Vorrichtung und Verfahren zur parallelen Aufbereitung von Biopolymeren

Also Published As

Publication number Publication date
US6720417B1 (en) 2004-04-13
AU6213298A (en) 1998-08-18
WO1998032877A1 (de) 1998-07-30
US20040166524A1 (en) 2004-08-26
JP2001511644A (ja) 2001-08-14
EP0964934A1 (de) 1999-12-22

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: ROCHE DIAGNOSTICS GMBH, 68305 MANNHEIM, DE

8141 Disposal/no request for examination