DE1957420A1 - Benzdiazepin-Derivate und Verfahren zu deren Herstellung - Google Patents

Benzdiazepin-Derivate und Verfahren zu deren Herstellung

Info

Publication number
DE1957420A1
DE1957420A1 DE19691957420 DE1957420A DE1957420A1 DE 1957420 A1 DE1957420 A1 DE 1957420A1 DE 19691957420 DE19691957420 DE 19691957420 DE 1957420 A DE1957420 A DE 1957420A DE 1957420 A1 DE1957420 A1 DE 1957420A1
Authority
DE
Germany
Prior art keywords
chloro
reaction
acid
methyl
benzene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19691957420
Other languages
German (de)
English (en)
Inventor
Kanji Moro
Minoru Shindo
Teizo Shinozaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8323868A external-priority patent/JPS4933190B1/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DE1957420A1 publication Critical patent/DE1957420A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C3/00—Flexible luggage; Handbags
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19691957420 1968-11-15 1969-11-14 Benzdiazepin-Derivate und Verfahren zu deren Herstellung Pending DE1957420A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8323868A JPS4933190B1 (enExample) 1968-11-15 1968-11-15
JP3125069 1969-04-24

Publications (1)

Publication Number Publication Date
DE1957420A1 true DE1957420A1 (de) 1970-06-18

Family

ID=26369703

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19691957420 Pending DE1957420A1 (de) 1968-11-15 1969-11-14 Benzdiazepin-Derivate und Verfahren zu deren Herstellung

Country Status (6)

Country Link
US (1) US3732294A (enExample)
CH (2) CH536308A (enExample)
DE (1) DE1957420A1 (enExample)
FR (1) FR2023406A1 (enExample)
GB (1) GB1235994A (enExample)
NL (1) NL150109B (enExample)

Also Published As

Publication number Publication date
NL150109B (nl) 1976-07-15
CH536308A (de) 1973-04-30
FR2023406A1 (enExample) 1970-08-21
GB1235994A (en) 1971-06-16
CH529101A (de) 1972-10-15
US3732294A (en) 1973-05-08
NL6917133A (enExample) 1970-05-20

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Legal Events

Date Code Title Description
SH Request for examination between 03.10.1968 and 22.04.1971