DE1695392A1 - Verfahren zur Herstellung von Piperazinderivaten - Google Patents
Verfahren zur Herstellung von PiperazinderivatenInfo
- Publication number
- DE1695392A1 DE1695392A1 DE19671695392 DE1695392A DE1695392A1 DE 1695392 A1 DE1695392 A1 DE 1695392A1 DE 19671695392 DE19671695392 DE 19671695392 DE 1695392 A DE1695392 A DE 1695392A DE 1695392 A1 DE1695392 A1 DE 1695392A1
- Authority
- DE
- Germany
- Prior art keywords
- general formula
- fluorophenyl
- given above
- meaning given
- pyridyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000004885 piperazines Chemical class 0.000 title claims 3
- 238000000034 method Methods 0.000 title claims 2
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 3
- 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000004198 2-fluorophenyl group Chemical group [H]C1=C([H])C(F)=C(*)C([H])=C1[H] 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 230000001760 anti-analgesic effect Effects 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 238000009835 boiling Methods 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- GLUUGHFHXGJENI-UHFFFAOYSA-N diethylenediamine Natural products C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 125000002541 furyl group Chemical group 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- -1 methyl- Chemical group 0.000 claims 1
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 claims 1
- 125000001544 thienyl group Chemical group 0.000 claims 1
- 125000001680 trimethoxyphenyl group Chemical group 0.000 claims 1
- 210000003608 fece Anatomy 0.000 description 3
- 239000010871 livestock manure Substances 0.000 description 3
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MC608A MC598A1 (fr) | 1966-02-16 | 1966-02-16 | Nouveaux composés chimiques et procédé pour leur préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1695392A1 true DE1695392A1 (de) | 1971-04-08 |
Family
ID=19737671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19671695392 Pending DE1695392A1 (de) | 1966-02-16 | 1967-02-10 | Verfahren zur Herstellung von Piperazinderivaten |
Country Status (7)
| Country | Link |
|---|---|
| CH (1) | CH478141A (enExample) |
| DE (1) | DE1695392A1 (enExample) |
| ES (1) | ES336777A1 (enExample) |
| FR (1) | FR6671M (enExample) |
| GB (1) | GB1110360A (enExample) |
| MC (1) | MC598A1 (enExample) |
| NL (1) | NL6702283A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005061427A1 (de) * | 2005-12-22 | 2007-06-28 | Grünenthal GmbH | Substituierte Oxadiazol-Derivate |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3005287A1 (de) * | 1980-02-13 | 1981-08-20 | Basf Ag, 6700 Ludwigshafen | Phenylpiperazinderivate von 1,3,4-oxadiazolylphenolen, ihre herstellung und diese enthaltende therapeutische mittel |
| AU2004229392A1 (en) | 2003-04-09 | 2004-10-28 | Exelixis, Inc. | Tie-2 modulators and methods of use |
| GB0510139D0 (en) | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B1 |
-
1966
- 1966-02-16 MC MC608A patent/MC598A1/fr unknown
-
1967
- 1967-01-27 FR FR92738A patent/FR6671M/fr not_active Expired
- 1967-02-06 GB GB5586/67A patent/GB1110360A/en not_active Expired
- 1967-02-07 CH CH182267A patent/CH478141A/fr not_active IP Right Cessation
- 1967-02-10 DE DE19671695392 patent/DE1695392A1/de active Pending
- 1967-02-13 ES ES336777A patent/ES336777A1/es not_active Expired
- 1967-02-15 NL NL6702283A patent/NL6702283A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005061427A1 (de) * | 2005-12-22 | 2007-06-28 | Grünenthal GmbH | Substituierte Oxadiazol-Derivate |
Also Published As
| Publication number | Publication date |
|---|---|
| MC598A1 (fr) | 1967-03-21 |
| FR6671M (enExample) | 1969-02-03 |
| ES336777A1 (es) | 1968-06-01 |
| NL6702283A (enExample) | 1967-08-17 |
| GB1110360A (en) | 1968-04-18 |
| CH478141A (fr) | 1969-09-15 |
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