DE1617628B1 - Verfahren zur Herstellung wässriger, steriler Arzneimittelsuspensionen - Google Patents

Verfahren zur Herstellung wässriger, steriler Arzneimittelsuspensionen

Info

Publication number
DE1617628B1
DE1617628B1 DE1966M0070838 DEM0070838A DE1617628B1 DE 1617628 B1 DE1617628 B1 DE 1617628B1 DE 1966M0070838 DE1966M0070838 DE 1966M0070838 DE M0070838 A DEM0070838 A DE M0070838A DE 1617628 B1 DE1617628 B1 DE 1617628B1
Authority
DE
Germany
Prior art keywords
sodium chloride
water
suspension
aqueous
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE1966M0070838
Other languages
German (de)
English (en)
Inventor
Neill Joseph Lawrence O
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1617628B1 publication Critical patent/DE1617628B1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE1966M0070838 1965-09-07 1966-09-06 Verfahren zur Herstellung wässriger, steriler Arzneimittelsuspensionen Pending DE1617628B1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48559265A 1965-09-07 1965-09-07

Publications (1)

Publication Number Publication Date
DE1617628B1 true DE1617628B1 (de) 1971-01-21

Family

ID=23928732

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1966M0070838 Pending DE1617628B1 (de) 1965-09-07 1966-09-06 Verfahren zur Herstellung wässriger, steriler Arzneimittelsuspensionen

Country Status (5)

Country Link
DE (1) DE1617628B1 (OSRAM)
ES (1) ES331228A1 (OSRAM)
FR (1) FR1546469A (OSRAM)
GB (1) GB1149648A (OSRAM)
NL (1) NL159010B (OSRAM)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0437368A1 (en) * 1990-01-12 1991-07-17 LABORATOIRES MERCK, SHARP & DOHME-CHIBRET Fluid ophthalmic composition based on lipid microparticles containing at least one active principle
DE102005009194A1 (de) * 2005-03-01 2006-09-14 Hpp-Hommel Pharmaceuticals Production Gmbh Verfahren zur Herstellung von polymorph stabilem Triamcinolonacetonid
WO2016092513A1 (en) * 2014-12-12 2016-06-16 Alfa Intes Industria Terapeutica Splendore S.R.L. Ophthalmic compositions for use in the treatment of the dry eye syndrome

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5537528B2 (OSRAM) * 1972-12-11 1980-09-29
US20070178051A1 (en) * 2006-01-27 2007-08-02 Elan Pharma International, Ltd. Sterilized nanoparticulate glucocorticosteroid formulations
CN115487153B (zh) * 2022-10-25 2023-11-03 成都青山利康药业股份有限公司 一种保护化合物的晶型的方法
CN115969784B (zh) * 2022-12-26 2025-10-21 昆明积大制药股份有限公司 曲安奈德注射液的制备方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0437368A1 (en) * 1990-01-12 1991-07-17 LABORATOIRES MERCK, SHARP & DOHME-CHIBRET Fluid ophthalmic composition based on lipid microparticles containing at least one active principle
DE102005009194A1 (de) * 2005-03-01 2006-09-14 Hpp-Hommel Pharmaceuticals Production Gmbh Verfahren zur Herstellung von polymorph stabilem Triamcinolonacetonid
DE102005009194B4 (de) * 2005-03-01 2006-12-14 Hpp-Hommel Pharmaceuticals Production Gmbh Verfahren zur Herstellung von polymorph stabilem Triamcinolonacetonid
WO2016092513A1 (en) * 2014-12-12 2016-06-16 Alfa Intes Industria Terapeutica Splendore S.R.L. Ophthalmic compositions for use in the treatment of the dry eye syndrome

Also Published As

Publication number Publication date
GB1149648A (en) 1969-04-23
NL159010B (nl) 1979-01-15
FR1546469A (fr) 1968-11-22
NL6612607A (OSRAM) 1967-03-08
ES331228A1 (es) 1967-07-01

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Legal Events

Date Code Title Description
E77 Valid patent as to the heymanns-index 1977