DE1518994A1 - Verfahren zur Herstellung von neuen Beta,10Alpha-Steroiden - Google Patents
Verfahren zur Herstellung von neuen Beta,10Alpha-SteroidenInfo
- Publication number
- DE1518994A1 DE1518994A1 DE19651518994 DE1518994A DE1518994A1 DE 1518994 A1 DE1518994 A1 DE 1518994A1 DE 19651518994 DE19651518994 DE 19651518994 DE 1518994 A DE1518994 A DE 1518994A DE 1518994 A1 DE1518994 A1 DE 1518994A1
- Authority
- DE
- Germany
- Prior art keywords
- androsta
- general formula
- acetoxy
- keto
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB291965A GB1139411A (en) | 1965-01-22 | 1965-01-22 | Preparation of 10-‡-methyl steroids |
| CH846564A CH454842A (de) | 1965-05-31 | 1965-05-31 | Verfahren zur Herstellung von neuen 9B,10a-Steroiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1518994A1 true DE1518994A1 (de) | 1969-09-25 |
Family
ID=25703347
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19651518994 Pending DE1518994A1 (de) | 1965-01-22 | 1965-06-03 | Verfahren zur Herstellung von neuen Beta,10Alpha-Steroiden |
| DE19651543274 Pending DE1543274A1 (de) | 1965-01-22 | 1965-06-24 | Verfahren zur Herstellung von 4-Keto-4,6-bisdehydro-6-halogen-9beta,10alpha-sterioden |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19651543274 Pending DE1543274A1 (de) | 1965-01-22 | 1965-06-24 | Verfahren zur Herstellung von 4-Keto-4,6-bisdehydro-6-halogen-9beta,10alpha-sterioden |
Country Status (14)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE667121A (US07118763-20061010-C00002.png) * | 1964-10-28 | |||
| IL23629A (en) * | 1965-01-22 | 1969-01-29 | Hoffmann La Roche | 9beta,10alpha-steroids and process for the manufacture thereof |
| GB1228801A (US07118763-20061010-C00002.png) * | 1967-07-11 | 1971-04-21 | ||
| US3937700A (en) * | 1970-03-04 | 1976-02-10 | U.S. Philips Corporation | Novel 1,2-methylene-17α-acyloxy (or improved hydroxy)-9β, 10α-steroid compounds of the pregnane series, pharmaceutic preparations on the basis of the novel compounds and methods of producing said compounds and preparations |
| US4898694A (en) * | 1987-11-25 | 1990-02-06 | Schwartz Arthur G | 17-Hydroxy-steroids |
| US20070082876A1 (en) * | 2005-09-30 | 2007-04-12 | Solvay Pharmaceuticals Gmbh | Novel C18 modified retrosteroids as progesterone receptor modulator compounds |
| US20070212751A1 (en) * | 2006-01-18 | 2007-09-13 | Solvay Pharmaceuticals Gmbh | Microbial method for the 11beta hydroxylation of 9beta, 10alpha-steriods |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL252417A (US07118763-20061010-C00002.png) * | 1959-06-08 | |||
| US3258473A (en) * | 1963-10-04 | 1966-06-28 | Syntex Corp | 17-dihaloacetate esters of 17alpha-hydroxy-21-desoxypregnane derivatives |
| IL23629A (en) * | 1965-01-22 | 1969-01-29 | Hoffmann La Roche | 9beta,10alpha-steroids and process for the manufacture thereof |
-
1965
- 1965-05-30 IL IL6523629A patent/IL23629A/xx unknown
- 1965-06-03 DE DE19651518994 patent/DE1518994A1/de active Pending
- 1965-06-16 FR FR20951A patent/FR4631M/fr not_active Expired
- 1965-06-22 BR BR170589/65A patent/BR6570589D0/pt unknown
- 1965-06-22 BE BE665762D patent/BE665762A/xx unknown
- 1965-06-23 SE SE08369/65A patent/SE331277B/xx unknown
- 1965-06-23 DK DK319165AA patent/DK120337B/da unknown
- 1965-06-23 IL IL6523785A patent/IL23785A/xx unknown
- 1965-06-23 FI FI1505/65A patent/FI41743B/fi active
- 1965-06-23 CH CH876665A patent/CH464188A/de unknown
- 1965-06-23 GB GB26557/65A patent/GB1087920A/en not_active Expired
- 1965-06-24 US US466817A patent/US3423433A/en not_active Expired - Lifetime
- 1965-06-24 FR FR22045A patent/FR1446515A/fr not_active Expired
- 1965-06-24 US US466818A patent/US3304314A/en not_active Expired - Lifetime
- 1965-06-24 AT AT573665A patent/AT261129B/de active
- 1965-06-24 DE DE19651543274 patent/DE1543274A1/de active Pending
- 1965-06-25 NL NL6508179A patent/NL6508179A/xx unknown
- 1965-06-25 NL NL6508148A patent/NL6508148A/xx unknown
- 1965-06-25 ES ES0314639A patent/ES314639A1/es not_active Expired
- 1965-06-25 DK DK324365AA patent/DK123352B/da unknown
- 1965-06-26 FR FR22465A patent/FR1439514A/fr not_active Expired
- 1965-06-28 BE BE666060A patent/BE666060A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES314639A1 (es) | 1966-02-16 |
| FI41743B (US07118763-20061010-C00002.png) | 1969-10-31 |
| NL6508179A (US07118763-20061010-C00002.png) | 1965-12-27 |
| CH464188A (de) | 1968-10-31 |
| FR1439514A (fr) | 1966-05-20 |
| BE666060A (US07118763-20061010-C00002.png) | 1965-12-28 |
| FR1446515A (fr) | 1966-07-22 |
| DK123352B (da) | 1972-06-12 |
| NL6508148A (US07118763-20061010-C00002.png) | 1966-06-27 |
| BR6570589D0 (pt) | 1973-08-02 |
| DE1543274A1 (de) | 1969-07-24 |
| US3304314A (en) | 1967-02-14 |
| IL23629A (en) | 1969-01-29 |
| GB1087920A (en) | 1967-10-18 |
| US3423433A (en) | 1969-01-21 |
| BE665762A (US07118763-20061010-C00002.png) | 1965-12-22 |
| DK120337B (da) | 1971-05-17 |
| AT261129B (de) | 1968-04-10 |
| FR4631M (US07118763-20061010-C00002.png) | 1966-11-28 |
| IL23785A (en) | 1969-09-25 |
| SE331277B (US07118763-20061010-C00002.png) | 1970-12-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DD227966A5 (de) | Verfahren zur herstellung neuer carbonsaeureester | |
| DE1518994A1 (de) | Verfahren zur Herstellung von neuen Beta,10Alpha-Steroiden | |
| DE3401680A1 (de) | 6(alpha),16ss-dimethylkortikoide | |
| EP0003341B1 (de) | 11,17-substituierte Pregnane, ihre Herstellung und Verwendung zur Herstellung von pharmazeutischen Präparaten | |
| DE1920145A1 (de) | Neue Steroide und deren Herstellung | |
| DE1593052C3 (de) | Verfahren zur Herstellung von 16-Methylen-19-norprogesteron-derivaten | |
| EP0023006B1 (de) | Verfahren zur Herstellung von ungesättigten Steroiden | |
| DE2636405C2 (de) | Δ↑1↑↑5↑-17α-Chloräthinyl- und -Propinylsteroide der Östranreihe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Präparate | |
| DE1668205C3 (de) | 16 alpha-Alkylthio-9beta, lOalpha-Steroide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate | |
| DE2602891A1 (de) | Neue 13-aethinyl-steroide und verfahren zu ihrer herstellung | |
| DE1668658B2 (de) | 16alpha-Methylverbindungen der Pregnanreihe sowie Verfahren zu deren Herstellung. Ausscheidung aus: 1418390 | |
| DE1643016C3 (de) | 1,2alpha-Methylensteroide, Verfahren zu deren Herstellung und diese Steroide enthaltende Mittel | |
| DE1468421C (de) | Neu 9beta,10alpha Steroide der Pregnanreihe und Verfahren zu ihrer Herstellung | |
| DE2508136C3 (de) | Neue Steroide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Mittel | |
| AT270887B (de) | Verfahren zur Herstellung von neuen 9β,10α-Steroiden | |
| DE1618511A1 (de) | Verfahren zur Herstellung von neuen 9ss 10alpha-Steroiden | |
| DE2441647A1 (de) | 17beta-aethinyl-3,17alpha-oestradiolverbindungen, verfahren zu ihrer herstellung, arzneimittel und 17beta-aethinyl-16alpha, 17alpha-epoxyoestran-3-olverbindungen | |
| DE1802962C3 (de) | Neue Galpha, 6beta-Dlfluorsteroide, Verfahren zu ihrer Herstellung, sowie diese enthaltende Mittel | |
| DE1443957C (de) | 9 alpha-Chlor- bzw. 9 alpha-Fluor-. 16 beta-methyl-prednisolon-17,21-diester und ein Verfahren zu deren Herstellung | |
| DE2533496A1 (de) | Neue difluorsteroide und verfahren zu ihrer herstellung | |
| DE1241825B (de) | Ver fahren zur Herstellung von 6 Chlor 4 6diLirverbindungen der Pregnan-, Androstan oder Cholestanreihe | |
| EP0078235A2 (de) | Dihalogenierte Steroide | |
| DE1618493A1 (de) | Verfahren zur Herstellung von halogenierten Steroiden | |
| DE1923746A1 (de) | 9beta,10Alpha-Steroide | |
| DE1177147B (de) | Verfahren zur Herstellung von 3-Enolaethern von 6-Formyl-3-oxo-?-steroiden |