DE123504T1 - Komplexe von technetium-99m mit alkylenaminoximen. - Google Patents
Komplexe von technetium-99m mit alkylenaminoximen.Info
- Publication number
- DE123504T1 DE123504T1 DE198484302615T DE84302615T DE123504T1 DE 123504 T1 DE123504 T1 DE 123504T1 DE 198484302615 T DE198484302615 T DE 198484302615T DE 84302615 T DE84302615 T DE 84302615T DE 123504 T1 DE123504 T1 DE 123504T1
- Authority
- DE
- Germany
- Prior art keywords
- complex
- technetium
- complex according
- alkyl
- bisoxime
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical class [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 title claims 5
- 125000004432 carbon atom Chemical group C* 0.000 claims 4
- 229940056501 technetium 99m Drugs 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 239000004215 Carbon black (E152) Substances 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 125000002877 alkyl aryl group Chemical group 0.000 claims 2
- 125000003710 aryl alkyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 229930195733 hydrocarbon Natural products 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 150000003512 tertiary amines Chemical class 0.000 claims 2
- 125000006539 C12 alkyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
- -1 C22 hydrocarbon Chemical class 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 150000001412 amines Chemical group 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 230000008499 blood brain barrier function Effects 0.000 claims 1
- 210000001218 blood-brain barrier Anatomy 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 1
- 150000001733 carboxylic acid esters Chemical class 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 230000000536 complexating effect Effects 0.000 claims 1
- 229940127043 diagnostic radiopharmaceutical Drugs 0.000 claims 1
- 150000002430 hydrocarbons Chemical class 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 230000002107 myocardial effect Effects 0.000 claims 1
- 150000002923 oximes Chemical class 0.000 claims 1
- 125000001749 primary amide group Chemical group 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 238000009877 rendering Methods 0.000 claims 1
- 230000000717 retained effect Effects 0.000 claims 1
- 150000003334 secondary amides Chemical class 0.000 claims 1
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 claims 1
- 229910052713 technetium Inorganic materials 0.000 claims 1
- GKLVYJBZJHMRIY-UHFFFAOYSA-N technetium atom Chemical compound [Tc] GKLVYJBZJHMRIY-UHFFFAOYSA-N 0.000 claims 1
- 150000003511 tertiary amides Chemical class 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
- C07C53/19—Acids containing three or more carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/488,184 US4615876A (en) | 1983-04-25 | 1983-04-25 | Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE123504T1 true DE123504T1 (de) | 1985-10-10 |
Family
ID=23938663
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE198484302615T Pending DE123504T1 (de) | 1983-04-25 | 1984-04-17 | Komplexe von technetium-99m mit alkylenaminoximen. |
| DE8484302615T Expired DE3479801D1 (en) | 1983-04-25 | 1984-04-17 | Complexes of technetium-99m with alkylene amine oximes |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8484302615T Expired DE3479801D1 (en) | 1983-04-25 | 1984-04-17 | Complexes of technetium-99m with alkylene amine oximes |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4615876A (https=) |
| EP (1) | EP0123504B1 (https=) |
| JP (2) | JPS6069090A (https=) |
| AU (1) | AU564636B2 (https=) |
| CA (1) | CA1231715A (https=) |
| CS (1) | CS271306B2 (https=) |
| DE (2) | DE123504T1 (https=) |
| DK (1) | DK173948B1 (https=) |
| ES (1) | ES8607977A1 (https=) |
| FI (1) | FI78706C (https=) |
| ZA (1) | ZA843069B (https=) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4980147A (en) * | 1984-06-25 | 1990-12-25 | University Of Utah Research Foundation | Radiolabeled technetium chelates for use in renal function determinations |
| GB8426845D0 (en) * | 1984-10-24 | 1984-11-28 | Amersham Int Plc | Complexes of technetium-99m |
| US4789543A (en) * | 1984-11-30 | 1988-12-06 | E. I. Du Pont De Nemours And Company | Neutral technetium 99-m complexes useful as radiodiagnostic agents |
| US4897255A (en) * | 1985-01-14 | 1990-01-30 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| US5175343A (en) * | 1985-01-14 | 1992-12-29 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| EP0194843B1 (en) * | 1985-03-11 | 1993-01-13 | AMERSHAM INTERNATIONAL plc | Complexes of technetium-99m with propylene amine oximes |
| US4705849A (en) * | 1985-04-15 | 1987-11-10 | E. R. Squibb & Sons, Inc. | Boronic acid adducts of technetium-99m dioxime complexes |
| US4746505A (en) * | 1985-04-26 | 1988-05-24 | President And Fellows Of Harvard College | Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands |
| US4770807A (en) * | 1985-07-31 | 1988-09-13 | Commissariat A L'energie Atomique | Novel extraction agents and novel propane diamides |
| GB8601003D0 (en) * | 1986-01-16 | 1986-02-19 | Amersham Int Plc | Labelling blood cells |
| US4714605A (en) * | 1986-10-14 | 1987-12-22 | E. R. Squibb & Sons, Inc. | Technetium-99m labeled dioxime complexes |
| GB8702062D0 (en) * | 1987-01-30 | 1987-03-04 | Amersham Int Plc | Metal complexes for diagnosis & therapy |
| US5279811A (en) | 1987-02-18 | 1994-01-18 | The Du Pont Merck Pharmaceutical Company | Ester-substituted diaminedithiols and radiolabeled complexes thereof |
| US4994560A (en) * | 1987-06-24 | 1991-02-19 | The Dow Chemical Company | Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies |
| WO1989001342A2 (en) * | 1987-08-07 | 1989-02-23 | Mallinckrodt, Inc. | Diagnostic or radiotherapeutic composition comprising a hydrogen containing compound |
| US4871836A (en) * | 1987-10-13 | 1989-10-03 | E. R. Squibb & Sons, Inc. | Boronic acid adducts of rhenium and radioactive isotopes of rhenium dioxime complexes |
| US4988496A (en) * | 1988-05-31 | 1991-01-29 | Neorx Corporation | Metal radionuclide chelating compounds for improved chelation kinetics |
| US5075099A (en) * | 1988-05-31 | 1991-12-24 | Neorx Corporation | Metal radionuclide chelating compounds for improved chelation kinetics |
| US4895960A (en) * | 1989-01-23 | 1990-01-23 | University Of Cincinnati | Cyclo substituted propyleneamine oxime and its use as a brain imaging agent |
| US5026829A (en) * | 1989-01-23 | 1991-06-25 | University Of Cincinnati | Cyclo substituted propyleneamine oxime and its use as a brain imaging agent |
| FR2646157B1 (fr) * | 1989-04-19 | 1991-08-30 | Ire Medgenix Sa | Ligands et complexes utiles notamment en imagerie medicale |
| FR2655339B2 (fr) * | 1989-04-19 | 1992-04-10 | Medgenix Group Sa | Composes et complexes utiles notamment en imagerie medicale. |
| US5118797A (en) * | 1989-08-28 | 1992-06-02 | E. R. Squibb & Sons, Inc. | Rhenium tris dioxime complexes |
| US5069900A (en) * | 1989-08-28 | 1991-12-03 | E. R. Squibb & Sons, Inc. | Boronic acid adducts of technetium-99m dioxime-imine complexes |
| DE3930674A1 (de) * | 1989-09-11 | 1991-03-21 | Diagnostikforschung Inst | Bifunktionelle chelatbildner zur komplexierung von tc- und re-isotopen, verfahren zu ihrer herstellung und darstellung von konjugaten daraus sowie deren verwendung in diagnostik und therapie |
| US5377681A (en) * | 1989-11-13 | 1995-01-03 | University Of Florida | Method of diagnosing impaired blood flow |
| US5026913A (en) * | 1989-12-12 | 1991-06-25 | Medi-Physics, Inc. | Hydrocarbylphenyl diaminodithiol derivatives |
| US5080884A (en) * | 1989-12-12 | 1992-01-14 | Medi-Physics, Inc. | Hydrocarbylphenyl diaminodithiol radionuclide complexes and their use in imaging |
| US5143713A (en) * | 1990-05-30 | 1992-09-01 | Board Of Regents, The University Of Texas System | 99m Tc labeled liposomes |
| DE4017439C2 (de) * | 1990-05-30 | 1994-06-23 | Deutsches Krebsforsch | Polyethersubstituierte Tumormittel |
| US5158760A (en) * | 1990-05-30 | 1992-10-27 | Board Of Regents, The University Of Texas System | 99m TC labeled liposomes |
| US5116598A (en) * | 1990-10-29 | 1992-05-26 | Mallinckrodt Medical, Inc. | N4 technetium-99 m complexes for use as radiopharmaceuticals |
| US5965107A (en) * | 1992-03-13 | 1999-10-12 | Diatide, Inc. | Technetium-99m labeled peptides for imaging |
| US5997844A (en) * | 1991-02-08 | 1999-12-07 | Diatide, Inc. | Technetium-99m labeled peptides for imaging |
| WO1992014492A1 (en) * | 1991-02-14 | 1992-09-03 | Mallinckrodt Medical, Inc. | In situ synthesis of radiopharmaceuticals |
| DE4107570A1 (de) * | 1991-03-07 | 1992-11-19 | Diagnostikforschung Inst | Chelate, deren metallkomplexe sowie ihre verwendung in diagnostik und therapie |
| GB9113487D0 (en) * | 1991-06-21 | 1991-08-07 | Amersham Int Plc | Agents for hypoxic cells |
| US5808091A (en) | 1991-10-29 | 1998-09-15 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia localizing moiety |
| NZ244613A (en) * | 1991-10-29 | 1996-05-28 | Bracco International B V Subst | A ligand containing a hypoxia-localising moiety, preparation thereof; a kit (optionally multivial) for preparing a metal complex containing the ligand |
| US6359120B1 (en) | 1991-10-29 | 2002-03-19 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia-localizing moiety |
| AU683015B2 (en) * | 1992-03-13 | 1997-10-30 | Diatech, Inc. | Technetium-99m labeled peptides for imaging inflammation |
| WO1994008949A2 (en) * | 1992-10-08 | 1994-04-28 | Amersham International Plc | Metal-oxime chelates for use as radiopharmaceutical agents |
| US5730130A (en) * | 1993-02-12 | 1998-03-24 | Johnson & Johnson Professional, Inc. | Localization cap for fiducial markers |
| US6517811B2 (en) | 1993-05-06 | 2003-02-11 | Research Corporation Technologies, Inc. | Compounds for cancer imaging and therapy |
| US5911970A (en) | 1993-05-06 | 1999-06-15 | Research Corporation Technologies, Inc. | Methods for cancer imaging and therapy using benzamine compounds |
| US5608110A (en) * | 1993-06-15 | 1997-03-04 | Bracco International B.V. | Heteroatom-bearing ligands and metal complexes thereof |
| CA2168652A1 (en) * | 1993-08-04 | 1995-02-16 | Colin Mill Archer | Radiometal complexes that localise in hypoxic tissue |
| CA2156605A1 (en) * | 1994-01-12 | 1995-07-20 | Bracco International B.V. | Ligands and metal complexes thereof |
| US6333971B2 (en) | 1995-06-07 | 2001-12-25 | George S. Allen | Fiducial marker |
| CA2366789C (en) | 1999-04-14 | 2010-09-28 | Biostream, Inc. | Fatty acid analogs for diagnosis of coronary artery disease |
| GB0015242D0 (en) * | 2000-06-22 | 2000-08-16 | Nycomed Amersham Plc | Stabiliser for radiopharmaceuticals |
| EP1490114A1 (en) * | 2002-04-01 | 2004-12-29 | Biostream, Inc. | Pendant fatty acid imaging agents |
| ES2358745T3 (es) * | 2004-11-22 | 2011-05-13 | Ge Healthcare As | Agentes de contraste para señalar matriz extracelular. |
| CU23844B1 (es) | 2009-04-17 | 2012-10-15 | Ct De Neurociencias De Cuba | Procedimiento de obtención de nuevos derivados de naftaleno para el diagnóstico in vivo de la enfermedad de alzheimer |
| US20130195756A1 (en) | 2012-01-31 | 2013-08-01 | General Electric Company | 99mTc IMAGING AGENTS AND METHODS OF USE |
| MX369008B (es) | 2014-03-27 | 2019-10-24 | Jubilant Generics Ltd | Un proceso mejorado para la preparación de exametazima. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4360511A (en) * | 1978-11-29 | 1982-11-23 | Medi-Physics, Inc. | Amines useful as brain imaging agents |
| US4363793A (en) * | 1979-08-30 | 1982-12-14 | State University Of New York | Diagnostic radiopharmaceuticals for localization in target tissues exhibiting a regional pH shift relative to surrounding tissues |
| US4352751A (en) * | 1979-09-10 | 1982-10-05 | Analytical Radiation Corporation | Species-linked diamine triacetic acids and their chelates |
| US4387087A (en) * | 1980-04-18 | 1983-06-07 | Research Corporation | Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging |
-
1983
- 1983-04-25 US US06/488,184 patent/US4615876A/en not_active Expired - Lifetime
-
1984
- 1984-04-17 DE DE198484302615T patent/DE123504T1/de active Pending
- 1984-04-17 EP EP84302615A patent/EP0123504B1/en not_active Expired
- 1984-04-17 DE DE8484302615T patent/DE3479801D1/de not_active Expired
- 1984-04-19 AU AU27118/84A patent/AU564636B2/en not_active Expired
- 1984-04-24 CA CA000452603A patent/CA1231715A/en not_active Expired
- 1984-04-24 ES ES531865A patent/ES8607977A1/es not_active Expired
- 1984-04-24 DK DK198402052A patent/DK173948B1/da not_active IP Right Cessation
- 1984-04-24 CS CS843030A patent/CS271306B2/cs unknown
- 1984-04-25 FI FI841622A patent/FI78706C/fi not_active IP Right Cessation
- 1984-04-25 JP JP59083613A patent/JPS6069090A/ja active Granted
- 1984-04-25 ZA ZA843069A patent/ZA843069B/xx unknown
-
1989
- 1989-08-21 JP JP1214737A patent/JPH02160795A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK173948B1 (da) | 2002-03-04 |
| CS271306B2 (en) | 1990-09-12 |
| ES531865A0 (es) | 1986-06-01 |
| ES8607977A1 (es) | 1986-06-01 |
| CS303084A2 (en) | 1990-02-12 |
| EP0123504A2 (en) | 1984-10-31 |
| FI78706B (fi) | 1989-05-31 |
| JPS6069090A (ja) | 1985-04-19 |
| JPH02160795A (ja) | 1990-06-20 |
| JPH0211593B2 (https=) | 1990-03-14 |
| CA1231715A (en) | 1988-01-19 |
| FI78706C (fi) | 1989-09-11 |
| EP0123504A3 (en) | 1986-03-26 |
| US4615876A (en) | 1986-10-07 |
| AU2711884A (en) | 1984-11-01 |
| JPH0544931B2 (https=) | 1993-07-07 |
| DE3479801D1 (en) | 1989-10-26 |
| ZA843069B (en) | 1984-11-28 |
| DK205284A (da) | 1984-10-26 |
| DK205284D0 (da) | 1984-04-24 |
| FI841622A0 (fi) | 1984-04-25 |
| AU564636B2 (en) | 1987-08-20 |
| EP0123504B1 (en) | 1989-09-20 |
| FI841622L (fi) | 1984-10-26 |
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