DE1091575B - Verfahren zur Herstellung amoebicid wirksamer N-Dichloracet-p-oxy-anilid-Ester - Google Patents
Verfahren zur Herstellung amoebicid wirksamer N-Dichloracet-p-oxy-anilid-EsterInfo
- Publication number
- DE1091575B DE1091575B DEB50336A DEB0050336A DE1091575B DE 1091575 B DE1091575 B DE 1091575B DE B50336 A DEB50336 A DE B50336A DE B0050336 A DEB0050336 A DE B0050336A DE 1091575 B DE1091575 B DE 1091575B
- Authority
- DE
- Germany
- Prior art keywords
- dichloroacet
- oxy
- anilide
- preparation
- amoebicidally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims description 7
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 claims description 4
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 3
- ZWZVWGITAAIFPS-UHFFFAOYSA-N thiophosgene Chemical compound ClC(Cl)=S ZWZVWGITAAIFPS-UHFFFAOYSA-N 0.000 claims description 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 2
- 125000000217 alkyl group Chemical group 0.000 claims description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 2
- 229910052760 oxygen Inorganic materials 0.000 claims description 2
- 239000001301 oxygen Substances 0.000 claims description 2
- 229910052717 sulfur Chemical group 0.000 claims description 2
- 239000011593 sulfur Chemical group 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 description 10
- 241000700159 Rattus Species 0.000 description 5
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 5
- 229940079593 drug Drugs 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 230000003569 amebicidal effect Effects 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- ZNQVEEAIQZEUHB-UHFFFAOYSA-N 2-ethoxyethanol Chemical compound CCOCCO ZNQVEEAIQZEUHB-UHFFFAOYSA-N 0.000 description 2
- 241000224489 Amoeba Species 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 241000224432 Entamoeba histolytica Species 0.000 description 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical class [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229940007078 entamoeba histolytica Drugs 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000003812 trophozoite Anatomy 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/18—Esters of thiophosphoric acids with hydroxyaryl compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB356471X | 1955-11-03 | ||
| GB90356X | 1956-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1091575B true DE1091575B (de) | 1960-10-27 |
Family
ID=26242602
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DEB50336A Pending DE1091575B (de) | 1955-11-03 | 1956-10-27 | Verfahren zur Herstellung amoebicid wirksamer N-Dichloracet-p-oxy-anilid-Ester |
| DEB42293A Pending DE1092932B (de) | 1955-11-03 | 1956-10-27 | Verfahren zur Herstellung amoebicid wirksamer N-Dichloracet-oxy-anilid-Ester |
| DEB50246A Pending DE1095844B (de) | 1955-11-03 | 1956-10-27 | Verfahren zur Herstellung amoebicid wirksamer Ester von p-Oxy-N-dichloracet-N-alkyl-aniliden und ihren Salzen |
| DEB50245A Pending DE1092933B (de) | 1955-11-03 | 1956-10-27 | Verfahren zur Herstellung amoebicid wirksamer Ester von p-Oxy-N-dichloracet-N-alkyl-aniliden |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DEB42293A Pending DE1092932B (de) | 1955-11-03 | 1956-10-27 | Verfahren zur Herstellung amoebicid wirksamer N-Dichloracet-oxy-anilid-Ester |
| DEB50246A Pending DE1095844B (de) | 1955-11-03 | 1956-10-27 | Verfahren zur Herstellung amoebicid wirksamer Ester von p-Oxy-N-dichloracet-N-alkyl-aniliden und ihren Salzen |
| DEB50245A Pending DE1092933B (de) | 1955-11-03 | 1956-10-27 | Verfahren zur Herstellung amoebicid wirksamer Ester von p-Oxy-N-dichloracet-N-alkyl-aniliden |
Country Status (5)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB855556A (en) * | 1958-05-06 | 1960-12-07 | Boots Pure Drug Co Ltd | New acetanilide derivatives |
| CH1085667A4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1967-08-01 | 1969-03-14 | ||
| DE2714440C2 (de) * | 1977-03-31 | 1982-10-21 | Siemens AG, 1000 Berlin und 8000 München | Verfahren zur Herstellung von Titanat-Keramik |
| FR2649977B1 (fr) * | 1989-07-18 | 1991-10-04 | Cird | Esters bi-aromatiques, leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique |
-
0
- NL NL211890D patent/NL211890A/xx unknown
- BE BE552250D patent/BE552250A/xx unknown
- NL NL96977D patent/NL96977C/xx active
-
1955
- 1955-11-03 GB GB31482/55A patent/GB794762A/en not_active Expired
-
1956
- 1956-10-27 DE DEB50336A patent/DE1091575B/de active Pending
- 1956-10-27 DE DEB42293A patent/DE1092932B/de active Pending
- 1956-10-27 DE DEB50246A patent/DE1095844B/de active Pending
- 1956-10-27 DE DEB50245A patent/DE1092933B/de active Pending
- 1956-11-02 CH CH356471D patent/CH356471A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL211890A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | |
| DE1095844B (de) | 1960-12-29 |
| DE1092933B (de) | 1960-11-17 |
| NL96977C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | |
| DE1092932B (de) | 1960-11-17 |
| GB794762A (en) | 1958-05-07 |
| BE552250A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | |
| CH356471A (fr) | 1961-08-31 |
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