DE10334187A1 - Substituierte 2-Aminotetraline zur Behandlung von Depressionen - Google Patents
Substituierte 2-Aminotetraline zur Behandlung von Depressionen Download PDFInfo
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- DE10334187A1 DE10334187A1 DE10334187A DE10334187A DE10334187A1 DE 10334187 A1 DE10334187 A1 DE 10334187A1 DE 10334187 A DE10334187 A DE 10334187A DE 10334187 A DE10334187 A DE 10334187A DE 10334187 A1 DE10334187 A1 DE 10334187A1
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- Prior art keywords
- depression
- use according
- alkyl
- acid
- compound
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- 238000011282 treatment Methods 0.000 title claims description 13
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- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- ARIWANIATODDMH-UHFFFAOYSA-N rac-1-monolauroylglycerol Chemical compound CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 description 1
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- CBQGYUDMJHNJBX-RTBURBONSA-N reboxetine Chemical compound CCOC1=CC=CC=C1O[C@H](C=1C=CC=CC=1)[C@@H]1OCCNC1 CBQGYUDMJHNJBX-RTBURBONSA-N 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
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- 230000000306 recurrent effect Effects 0.000 description 1
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- TXHZXHICDBAVJW-UHFFFAOYSA-N rizatriptan Chemical compound C=1[C]2C(CCN(C)C)=CN=C2C=CC=1CN1C=NC=N1 TXHZXHICDBAVJW-UHFFFAOYSA-N 0.000 description 1
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- 208000012672 seasonal affective disease Diseases 0.000 description 1
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- VGKDLMBJGBXTGI-SJCJKPOMSA-N sertraline Chemical compound C1([C@@H]2CC[C@@H](C3=CC=CC=C32)NC)=CC=C(Cl)C(Cl)=C1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 0.000 description 1
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- JOFWLTCLBGQGBO-UHFFFAOYSA-N triazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NN=C2CN=C1C1=CC=CC=C1Cl JOFWLTCLBGQGBO-UHFFFAOYSA-N 0.000 description 1
- 239000003029 tricyclic antidepressant agent Substances 0.000 description 1
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- TUUBOHWZSQXCSW-UHFFFAOYSA-N vanillic acid Natural products COC1=CC(O)=CC(C(O)=O)=C1 TUUBOHWZSQXCSW-UHFFFAOYSA-N 0.000 description 1
- HUNXMJYCHXQEGX-UHFFFAOYSA-N zaleplon Chemical compound CCN(C(C)=O)C1=CC=CC(C=2N3N=CC(=C3N=CC=2)C#N)=C1 HUNXMJYCHXQEGX-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Priority Applications (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10334187A DE10334187A1 (de) | 2003-07-26 | 2003-07-26 | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
| CA2532804A CA2532804C (en) | 2003-07-26 | 2004-07-22 | Substituted 2-aminotetralin for the treatment of depression |
| AU2004258698A AU2004258698A1 (en) | 2003-07-26 | 2004-07-22 | Substituted 2-aminotetralin for the treatment of depression |
| ES04763387T ES2291914T3 (es) | 2003-07-26 | 2004-07-22 | 2-amino-tetralinas sustituidas, destinadas al tratamiento de depresiones. |
| DE502004005033T DE502004005033D1 (de) | 2003-07-26 | 2004-07-22 | Substituierte 2-aminotetraline zur behandlung von depressionen |
| EA200600223A EA009870B1 (ru) | 2003-07-26 | 2004-07-22 | Замещённый 2-аминотетралин для лечения депрессии |
| HK06111735.1A HK1091121B (en) | 2003-07-26 | 2004-07-22 | Substituted 2-aminotetralins for the treatment of depressions |
| CN2004800216477A CN1832734B (zh) | 2003-07-26 | 2004-07-22 | 用于治疗抑郁症的取代的2-氨基1,2,3,4-四氢化萘 |
| JP2006521477A JP2007500155A (ja) | 2003-07-26 | 2004-07-22 | うつ病の治療のための置換した２−アミノテトラリン |
| PCT/EP2004/008169 WO2005009425A1 (de) | 2003-07-26 | 2004-07-22 | Substituierte 2-aminotetraline zur behandlung von depressionen |
| US10/565,713 US20070072917A1 (en) | 2003-07-26 | 2004-07-22 | Substituted 2-aminotetralin for the treatment of depression |
| MXPA06000865A MXPA06000865A (es) | 2003-07-26 | 2004-07-22 | 2-aminotetralina substituida para eltratamiento de depresion. |
| BRPI0412999-7A BRPI0412999A (pt) | 2003-07-26 | 2004-07-22 | 2-aminotetralina substituìda para tratamento de depressão |
| KR1020067001812A KR101160699B1 (ko) | 2003-07-26 | 2004-07-22 | 우울증 치료용의 치환된 2-아미노테트라린 |
| UAA200600562A UA83233C2 (ru) | 2003-07-26 | 2004-07-22 | Замещенный 2-аминотетралин для лечения депрессии |
| EP04763387A EP1648433B1 (de) | 2003-07-26 | 2004-07-22 | Substituierte 2-aminotetraline zur behandlung von depressionen |
| AT04763387T ATE373474T1 (de) | 2003-07-26 | 2004-07-22 | Substituierte 2-aminotetraline zur behandlung von depressionen |
| ZA200600343A ZA200600343B (en) | 2003-07-26 | 2006-01-10 | Substituted 2-aminotetralin for the treatment of depression |
| IL173062A IL173062A (en) | 2003-07-26 | 2006-01-10 | Use of substituted 2-aminotetralins for the manufacture of a medicament for the treatment of depression |
| IS8230A IS2696B (is) | 2003-07-26 | 2006-01-12 | Setin 2-amínótetralín fyrir meðhöndlunina á geðdeyfð |
| NO20060847A NO20060847L (no) | 2003-07-26 | 2006-02-21 | Substituert 2-aminotetralin til behandling av depresjon |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10334187A DE10334187A1 (de) | 2003-07-26 | 2003-07-26 | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10334187A1 true DE10334187A1 (de) | 2005-03-03 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| DE10334187A Ceased DE10334187A1 (de) | 2003-07-26 | 2003-07-26 | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
| DE502004005033T Expired - Lifetime DE502004005033D1 (de) | 2003-07-26 | 2004-07-22 | Substituierte 2-aminotetraline zur behandlung von depressionen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| DE502004005033T Expired - Lifetime DE502004005033D1 (de) | 2003-07-26 | 2004-07-22 | Substituierte 2-aminotetraline zur behandlung von depressionen |
Country Status (19)
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| EP (1) | EP1648433B1 (enExample) |
| JP (1) | JP2007500155A (enExample) |
| KR (1) | KR101160699B1 (enExample) |
| CN (1) | CN1832734B (enExample) |
| AT (1) | ATE373474T1 (enExample) |
| AU (1) | AU2004258698A1 (enExample) |
| BR (1) | BRPI0412999A (enExample) |
| CA (1) | CA2532804C (enExample) |
| DE (2) | DE10334187A1 (enExample) |
| EA (1) | EA009870B1 (enExample) |
| ES (1) | ES2291914T3 (enExample) |
| IL (1) | IL173062A (enExample) |
| IS (1) | IS2696B (enExample) |
| MX (1) | MXPA06000865A (enExample) |
| NO (1) | NO20060847L (enExample) |
| UA (1) | UA83233C2 (enExample) |
| WO (1) | WO2005009425A1 (enExample) |
| ZA (1) | ZA200600343B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8883205B2 (en) | 2006-02-10 | 2014-11-11 | Biogenerics Pharma Gmbh | Microtablet-based pharmaceutical preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE10041479A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
| US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
| US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
| DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| US8246979B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| ATE295726T1 (de) | 2002-12-02 | 2005-06-15 | Sanol Arznei Schwarz Gmbh | Verabreichung von rotigotine zur behandlung der parkinson'schen krankheit durch iontophorese |
| DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
| DE10361258A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
| DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
| EP1976495A2 (en) * | 2006-01-06 | 2008-10-08 | Aarhus Universitet | Compounds acting on the serotonin transporter |
| TWI392670B (zh) | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途 |
| CA2682200C (en) | 2007-03-19 | 2015-01-13 | Vita Sciences, Llc | Transdermal patch and method for delivery of vitamin b12 |
| EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
| HRP20150956T1 (hr) | 2007-11-28 | 2016-01-15 | Ucb Pharma Gmbh | Polimorfni oblik rotigotina |
| EP2098511A1 (en) | 2008-03-07 | 2009-09-09 | Solvias AG | Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring |
| EP2281559A1 (en) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
| US8296420B2 (en) * | 2009-09-18 | 2012-10-23 | Hitachi, Ltd. | Method and apparatus for constructing a DHT-based global namespace |
| JP5815556B2 (ja) | 2009-12-22 | 2015-11-17 | ウーツェーベー ファルマ ゲーエムベーハーＵｃｂ Ｐｈａｒｍａ Ｇｍｂｈ | 非結晶形態のロチゴチンの固体分散体を安定化するためのポリビニルピロリドン |
| CN103768010B (zh) * | 2012-10-22 | 2016-05-25 | 苏州药明康德新药开发股份有限公司 | 采用磺丁基-β-环糊精配制高浓度四氢化萘类化合物均一稳定溶液的方法 |
| CN103768043B (zh) * | 2012-10-22 | 2015-12-09 | 苏州药明康德新药开发股份有限公司 | 采用羟丙基-β-环糊精配制四氢化萘类化合物均一稳定溶液的方法 |
| AU2021368924B2 (en) * | 2020-10-27 | 2024-07-11 | Guangzhou Henovcom Bioscience Co., Ltd. | Tetrahydronaphthalene compounds, pharmaceutical compositions, and uses thereof |
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| DE3062971D1 (en) * | 1979-09-14 | 1983-06-09 | Sandoz Ag | Derivatives of tetraline, their preparation and medicaments containing these compounds |
| US4556676A (en) * | 1979-11-01 | 1985-12-03 | Pfizer Inc. | Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
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| DE3315272C2 (de) * | 1983-04-27 | 1986-03-27 | Lohmann Gmbh & Co Kg, 5450 Neuwied | Pharmazeutisches Produkt und Verfahren zu seiner Herstellung |
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2003
- 2003-07-26 DE DE10334187A patent/DE10334187A1/de not_active Ceased
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2004
- 2004-07-22 EP EP04763387A patent/EP1648433B1/de not_active Expired - Lifetime
- 2004-07-22 CA CA2532804A patent/CA2532804C/en not_active Expired - Fee Related
- 2004-07-22 ES ES04763387T patent/ES2291914T3/es not_active Expired - Lifetime
- 2004-07-22 MX MXPA06000865A patent/MXPA06000865A/es active IP Right Grant
- 2004-07-22 BR BRPI0412999-7A patent/BRPI0412999A/pt not_active IP Right Cessation
- 2004-07-22 UA UAA200600562A patent/UA83233C2/ru unknown
- 2004-07-22 AT AT04763387T patent/ATE373474T1/de not_active IP Right Cessation
- 2004-07-22 KR KR1020067001812A patent/KR101160699B1/ko not_active Expired - Fee Related
- 2004-07-22 DE DE502004005033T patent/DE502004005033D1/de not_active Expired - Lifetime
- 2004-07-22 AU AU2004258698A patent/AU2004258698A1/en not_active Abandoned
- 2004-07-22 WO PCT/EP2004/008169 patent/WO2005009425A1/de not_active Ceased
- 2004-07-22 US US10/565,713 patent/US20070072917A1/en not_active Abandoned
- 2004-07-22 JP JP2006521477A patent/JP2007500155A/ja active Pending
- 2004-07-22 CN CN2004800216477A patent/CN1832734B/zh not_active Expired - Fee Related
- 2004-07-22 EA EA200600223A patent/EA009870B1/ru not_active IP Right Cessation
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2006
- 2006-01-10 IL IL173062A patent/IL173062A/en not_active IP Right Cessation
- 2006-01-10 ZA ZA200600343A patent/ZA200600343B/xx unknown
- 2006-01-12 IS IS8230A patent/IS2696B/is unknown
- 2006-02-21 NO NO20060847A patent/NO20060847L/no not_active Application Discontinuation
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8883205B2 (en) | 2006-02-10 | 2014-11-11 | Biogenerics Pharma Gmbh | Microtablet-based pharmaceutical preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200600343B (en) | 2006-11-29 |
| WO2005009425A1 (de) | 2005-02-03 |
| KR101160699B1 (ko) | 2012-06-28 |
| IS8230A (is) | 2006-01-12 |
| EA009870B1 (ru) | 2008-04-28 |
| EP1648433B1 (de) | 2007-09-19 |
| MXPA06000865A (es) | 2006-05-04 |
| DE502004005033D1 (de) | 2007-10-31 |
| CA2532804A1 (en) | 2005-02-03 |
| AU2004258698A1 (en) | 2005-02-03 |
| CA2532804C (en) | 2012-09-25 |
| EP1648433A1 (de) | 2006-04-26 |
| IS2696B (is) | 2010-11-15 |
| EA200600223A1 (ru) | 2006-08-25 |
| IL173062A0 (en) | 2006-06-11 |
| UA83233C2 (ru) | 2008-06-25 |
| CN1832734B (zh) | 2010-09-29 |
| ES2291914T3 (es) | 2008-03-01 |
| US20070072917A1 (en) | 2007-03-29 |
| CN1832734A (zh) | 2006-09-13 |
| IL173062A (en) | 2011-12-29 |
| NO20060847L (no) | 2006-02-21 |
| KR20060052898A (ko) | 2006-05-19 |
| ATE373474T1 (de) | 2007-10-15 |
| JP2007500155A (ja) | 2007-01-11 |
| BRPI0412999A (pt) | 2006-10-03 |
| HK1091121A1 (en) | 2007-01-12 |
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