ATE373474T1 - Substituierte 2-aminotetraline zur behandlung von depressionen - Google Patents
Substituierte 2-aminotetraline zur behandlung von depressionenInfo
- Publication number
- ATE373474T1 ATE373474T1 AT04763387T AT04763387T ATE373474T1 AT E373474 T1 ATE373474 T1 AT E373474T1 AT 04763387 T AT04763387 T AT 04763387T AT 04763387 T AT04763387 T AT 04763387T AT E373474 T1 ATE373474 T1 AT E373474T1
- Authority
- AT
- Austria
- Prior art keywords
- depression
- aminotetraline
- substituted
- treatment
- racemates
- Prior art date
Links
- LCGFVWKNXLRFIF-UHFFFAOYSA-N 1,2,3,4-tetrahydronaphthalen-2-amine Chemical class C1=CC=C2CC(N)CCC2=C1 LCGFVWKNXLRFIF-UHFFFAOYSA-N 0.000 title 1
- 208000020401 Depressive disease Diseases 0.000 title 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10334187A DE10334187A1 (de) | 2003-07-26 | 2003-07-26 | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE373474T1 true ATE373474T1 (de) | 2007-10-15 |
Family
ID=34088861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04763387T ATE373474T1 (de) | 2003-07-26 | 2004-07-22 | Substituierte 2-aminotetraline zur behandlung von depressionen |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20070072917A1 (enExample) |
| EP (1) | EP1648433B1 (enExample) |
| JP (1) | JP2007500155A (enExample) |
| KR (1) | KR101160699B1 (enExample) |
| CN (1) | CN1832734B (enExample) |
| AT (1) | ATE373474T1 (enExample) |
| AU (1) | AU2004258698A1 (enExample) |
| BR (1) | BRPI0412999A (enExample) |
| CA (1) | CA2532804C (enExample) |
| DE (2) | DE10334187A1 (enExample) |
| EA (1) | EA009870B1 (enExample) |
| ES (1) | ES2291914T3 (enExample) |
| IL (1) | IL173062A (enExample) |
| IS (1) | IS2696B (enExample) |
| MX (1) | MXPA06000865A (enExample) |
| NO (1) | NO20060847L (enExample) |
| UA (1) | UA83233C2 (enExample) |
| WO (1) | WO2005009425A1 (enExample) |
| ZA (1) | ZA200600343B (enExample) |
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|---|---|---|---|---|
| DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE10041479A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
| US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
| US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
| US8211462B2 (en) | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| EP1426049B1 (en) | 2002-12-02 | 2005-05-18 | Schwarz Pharma Ag | Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease |
| DE10261696A1 (de) * | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
| DE10361258A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
| DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
| EP1976495A2 (en) * | 2006-01-06 | 2008-10-08 | Aarhus Universitet | Compounds acting on the serotonin transporter |
| DE102006006532B4 (de) | 2006-02-10 | 2007-11-08 | Biogenerics Pharma Gmbh | Pharmazeutische Zubereitung |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
| EP2124907B1 (en) | 2007-03-19 | 2018-05-30 | Vita Sciences, Llc | Transdermal patch and method for delivery of vitamin b12 |
| EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
| RS54235B1 (sr) * | 2007-11-28 | 2015-12-31 | Ucb Pharma Gmbh | Polimorfni oblik rotigotina |
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| US8296420B2 (en) * | 2009-09-18 | 2012-10-23 | Hitachi, Ltd. | Method and apparatus for constructing a DHT-based global namespace |
| BR112012017737A8 (pt) | 2009-12-22 | 2018-04-17 | Lts Lohmann Therapie Systeme Ag | polivinilpirrolidona para a estabilização de uma dispersão sólida da forma não cristalina de rotigotina. |
| CN103768010B (zh) * | 2012-10-22 | 2016-05-25 | 苏州药明康德新药开发股份有限公司 | 采用磺丁基-β-环糊精配制高浓度四氢化萘类化合物均一稳定溶液的方法 |
| CN103768043B (zh) * | 2012-10-22 | 2015-12-09 | 苏州药明康德新药开发股份有限公司 | 采用羟丙基-β-环糊精配制四氢化萘类化合物均一稳定溶液的方法 |
| AU2021368924B2 (en) * | 2020-10-27 | 2024-07-11 | Guangzhou Henovcom Bioscience Co., Ltd. | Tetrahydronaphthalene compounds, pharmaceutical compositions, and uses thereof |
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| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
| RS54235B1 (sr) * | 2007-11-28 | 2015-12-31 | Ucb Pharma Gmbh | Polimorfni oblik rotigotina |
| EP2281559A1 (en) * | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
| BR112012017737A8 (pt) * | 2009-12-22 | 2018-04-17 | Lts Lohmann Therapie Systeme Ag | polivinilpirrolidona para a estabilização de uma dispersão sólida da forma não cristalina de rotigotina. |
-
2003
- 2003-07-26 DE DE10334187A patent/DE10334187A1/de not_active Ceased
-
2004
- 2004-07-22 ES ES04763387T patent/ES2291914T3/es not_active Expired - Lifetime
- 2004-07-22 EA EA200600223A patent/EA009870B1/ru not_active IP Right Cessation
- 2004-07-22 UA UAA200600562A patent/UA83233C2/ru unknown
- 2004-07-22 EP EP04763387A patent/EP1648433B1/de not_active Expired - Lifetime
- 2004-07-22 DE DE502004005033T patent/DE502004005033D1/de not_active Expired - Lifetime
- 2004-07-22 AU AU2004258698A patent/AU2004258698A1/en not_active Abandoned
- 2004-07-22 CN CN2004800216477A patent/CN1832734B/zh not_active Expired - Fee Related
- 2004-07-22 CA CA2532804A patent/CA2532804C/en not_active Expired - Fee Related
- 2004-07-22 JP JP2006521477A patent/JP2007500155A/ja active Pending
- 2004-07-22 US US10/565,713 patent/US20070072917A1/en not_active Abandoned
- 2004-07-22 AT AT04763387T patent/ATE373474T1/de not_active IP Right Cessation
- 2004-07-22 KR KR1020067001812A patent/KR101160699B1/ko not_active Expired - Fee Related
- 2004-07-22 BR BRPI0412999-7A patent/BRPI0412999A/pt not_active IP Right Cessation
- 2004-07-22 WO PCT/EP2004/008169 patent/WO2005009425A1/de not_active Ceased
- 2004-07-22 MX MXPA06000865A patent/MXPA06000865A/es active IP Right Grant
-
2006
- 2006-01-10 IL IL173062A patent/IL173062A/en not_active IP Right Cessation
- 2006-01-10 ZA ZA200600343A patent/ZA200600343B/xx unknown
- 2006-01-12 IS IS8230A patent/IS2696B/is unknown
- 2006-02-21 NO NO20060847A patent/NO20060847L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20060847L (no) | 2006-02-21 |
| MXPA06000865A (es) | 2006-05-04 |
| IS2696B (is) | 2010-11-15 |
| KR20060052898A (ko) | 2006-05-19 |
| CN1832734A (zh) | 2006-09-13 |
| EP1648433B1 (de) | 2007-09-19 |
| ES2291914T3 (es) | 2008-03-01 |
| AU2004258698A1 (en) | 2005-02-03 |
| US20070072917A1 (en) | 2007-03-29 |
| IL173062A0 (en) | 2006-06-11 |
| EP1648433A1 (de) | 2006-04-26 |
| BRPI0412999A (pt) | 2006-10-03 |
| ZA200600343B (en) | 2006-11-29 |
| IL173062A (en) | 2011-12-29 |
| DE10334187A1 (de) | 2005-03-03 |
| WO2005009425A1 (de) | 2005-02-03 |
| HK1091121A1 (en) | 2007-01-12 |
| CN1832734B (zh) | 2010-09-29 |
| CA2532804C (en) | 2012-09-25 |
| DE502004005033D1 (de) | 2007-10-31 |
| KR101160699B1 (ko) | 2012-06-28 |
| UA83233C2 (ru) | 2008-06-25 |
| IS8230A (is) | 2006-01-12 |
| CA2532804A1 (en) | 2005-02-03 |
| EA009870B1 (ru) | 2008-04-28 |
| EA200600223A1 (ru) | 2006-08-25 |
| JP2007500155A (ja) | 2007-01-11 |
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| Date | Code | Title | Description |
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| REN | Ceased due to non-payment of the annual fee |