DE10226462A1 - Fluorierte Cycloalkyl-derivatisierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament - Google Patents
Fluorierte Cycloalkyl-derivatisierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes MedikamentInfo
- Publication number
- DE10226462A1 DE10226462A1 DE10226462A DE10226462A DE10226462A1 DE 10226462 A1 DE10226462 A1 DE 10226462A1 DE 10226462 A DE10226462 A DE 10226462A DE 10226462 A DE10226462 A DE 10226462A DE 10226462 A1 DE10226462 A1 DE 10226462A1
- Authority
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- Germany
- Prior art keywords
- compound
- hydrogen
- preparation
- treatment
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
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- C—CHEMISTRY; METALLURGY
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- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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Priority Applications (30)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10226462A DE10226462A1 (de) | 2002-06-13 | 2002-06-13 | Fluorierte Cycloalkyl-derivatisierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
| MXPA04011361A MXPA04011361A (es) | 2002-06-13 | 2003-05-05 | Pentafluorosulfanilbenzoilguanidinas, procedimiento para su preparacion, su uso como medicamento o agente de diagnostico, asi como medicamento que las comprende. |
| CNB038136139A CN1295213C (zh) | 2002-06-13 | 2003-06-02 | 氟化环烷基衍生的苯甲酰基胍及其作为药物的用途 |
| HK05108396.8A HK1076449B (en) | 2002-06-13 | 2003-06-02 | Fluorinated cycloalkyl-derivatised benzoylguanidines and their use as a medicament |
| EP09005497A EP2103598A1 (de) | 2002-06-13 | 2003-06-02 | Fluorierte Cycloalkyl-derivatisierte Benzoylguanidine, Verfahren zu ihre Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
| HR20041175A HRP20041175A2 (en) | 2002-06-13 | 2003-06-02 | Fluorinated cycloalkyl-derivatised benzoylguanidines and their use as a medicament |
| PCT/EP2003/005738 WO2003106410A1 (de) | 2002-06-13 | 2003-06-02 | Fluorierte cycloalkyl-derivatisierte benzoylguanidine und ihre verwendung als medikament |
| ES03759904T ES2333216T3 (es) | 2002-06-13 | 2003-06-02 | Benzoilguanidinas fluoradas cicloalquil-derivadas y su uso como medicamento. |
| KR10-2004-7020290A KR20050010052A (ko) | 2002-06-13 | 2003-06-02 | 불소화 사이클로알킬-유도체화된 벤조일구아니딘 및약제로서 이의 용도 |
| EP03759904A EP1515947B1 (de) | 2002-06-13 | 2003-06-02 | Fluorierte cycloalkyl-derivatisierte benzoylguanidine und ihre verwendung als medikament |
| JP2004513243A JP4383343B2 (ja) | 2002-06-13 | 2003-06-02 | フッ素化シクロアルキル誘導体化ベンゾイルグアニジン及び薬物としてのそれらの使用 |
| DK03759904.0T DK1515947T3 (da) | 2002-06-13 | 2003-06-02 | Flourerede cycloalkyl-derivatiserede benzoylguanidiner og deres anvendelse som medikament |
| PL03372054A PL372054A1 (en) | 2002-06-13 | 2003-06-02 | Fluorinated cycloalkyl-derivatised benzoylguanidines and their use as a medicament |
| BR0312134-8A BR0312134A (pt) | 2002-06-13 | 2003-06-02 | Benzoilguanidinas derivadas de cicloalquilas fluoradas e seu emprego como medicamento |
| US10/452,556 US6878748B2 (en) | 2002-06-13 | 2003-06-02 | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them |
| AU2003250821A AU2003250821B8 (en) | 2002-06-13 | 2003-06-02 | Fluorinated cycloalkyl-derivatised benzoylguanidines and their use as a medicament |
| DE50311897T DE50311897D1 (de) | 2002-06-13 | 2003-06-02 | Fluorierte cycloalkyl-derivatisierte benzoylguanidine und ihre verwendung als medikament |
| YUP-1059/04A RS105904A (sr) | 2002-06-13 | 2003-06-02 | Benzoilgvanidni derivatizovani fluorovanim cikloalkilima, postupak za njihovu proizvodnju i njihova primena kao leka |
| CA002489245A CA2489245A1 (en) | 2002-06-13 | 2003-06-02 | Fluorinated cycloalkyl-derivatized benzoylguanidines and their use as a medicament |
| RU2005100508/04A RU2305093C2 (ru) | 2002-06-13 | 2003-06-02 | Фторированные циклоалкилзамещенные бензоилгуанидины, способ их получения, их применение в качестве лекарственного средства, а также содержащее их лекарственное средство |
| PT03759904T PT1515947E (pt) | 2002-06-13 | 2003-06-02 | Benzoilguanidinas fluoradas derivatizadas com cicloalquilo e sua utilização como medicamento |
| MXPA04012231A MXPA04012231A (es) | 2002-06-13 | 2003-06-02 | Benzoilguanidinas cicloalquilderivadas fluoradas y su uso como medicamento. |
| AT03759904T ATE442353T1 (de) | 2002-06-13 | 2003-06-02 | Fluorierte cycloalkyl-derivatisierte benzoylguanidine und ihre verwendung als medikament |
| PE2003000580A PE20040559A1 (es) | 2002-06-13 | 2003-06-11 | Benzoilguanidinas cicloalquilderivadas fluoradas, procedimiento para su preparacion y medicamentos que las contienen |
| TW092115780A TWI291460B (en) | 2002-06-13 | 2003-06-11 | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their use as medicament, and medicament containing them |
| ARP030102093A AR040201A1 (es) | 2002-06-13 | 2003-06-11 | Benzoilguanidinas cicloalquilderivadas fluoradas, su uso como medicamento y medicamentos que las contienen |
| MYPI20032196A MY130810A (en) | 2002-06-13 | 2003-06-12 | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their use as medicament, and medicament containing them |
| ZA200409418A ZA200409418B (en) | 2002-06-13 | 2004-11-23 | Fluorinated cycloalkyl-derivatised benzoylguanidines and their use as a medicament |
| MA27988A MA27234A1 (fr) | 2002-06-13 | 2004-12-08 | Benzoylguanidines a fonctionnalite cycloalkyle fluore et leur utilisation comme medicament |
| NO20050078A NO20050078L (no) | 2002-06-13 | 2005-01-06 | Fluorerte sykloalkyl-derivatiserte benzoylguanidiner og deres anvendelse som medikament |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10226462A DE10226462A1 (de) | 2002-06-13 | 2002-06-13 | Fluorierte Cycloalkyl-derivatisierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
Publications (1)
| Publication Number | Publication Date |
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| DE10226462A1 true DE10226462A1 (de) | 2003-12-24 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10226462A Withdrawn DE10226462A1 (de) | 2002-06-13 | 2002-06-13 | Fluorierte Cycloalkyl-derivatisierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
| DE50311897T Expired - Lifetime DE50311897D1 (de) | 2002-06-13 | 2003-06-02 | Fluorierte cycloalkyl-derivatisierte benzoylguanidine und ihre verwendung als medikament |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE50311897T Expired - Lifetime DE50311897D1 (de) | 2002-06-13 | 2003-06-02 | Fluorierte cycloalkyl-derivatisierte benzoylguanidine und ihre verwendung als medikament |
Country Status (25)
| Country | Link |
|---|---|
| EP (2) | EP2103598A1 (enExample) |
| JP (1) | JP4383343B2 (enExample) |
| KR (1) | KR20050010052A (enExample) |
| CN (1) | CN1295213C (enExample) |
| AR (1) | AR040201A1 (enExample) |
| AT (1) | ATE442353T1 (enExample) |
| AU (1) | AU2003250821B8 (enExample) |
| BR (1) | BR0312134A (enExample) |
| CA (1) | CA2489245A1 (enExample) |
| DE (2) | DE10226462A1 (enExample) |
| DK (1) | DK1515947T3 (enExample) |
| ES (1) | ES2333216T3 (enExample) |
| HR (1) | HRP20041175A2 (enExample) |
| MA (1) | MA27234A1 (enExample) |
| MX (2) | MXPA04011361A (enExample) |
| MY (1) | MY130810A (enExample) |
| NO (1) | NO20050078L (enExample) |
| PE (1) | PE20040559A1 (enExample) |
| PL (1) | PL372054A1 (enExample) |
| PT (1) | PT1515947E (enExample) |
| RS (1) | RS105904A (enExample) |
| RU (1) | RU2305093C2 (enExample) |
| TW (1) | TWI291460B (enExample) |
| WO (1) | WO2003106410A1 (enExample) |
| ZA (1) | ZA200409418B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006027130A1 (de) * | 2004-09-11 | 2006-03-16 | Sanofi-Aventis Deutschland Gmbh | Pentafluorsulfanylphenyl-substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum sowie sie enthaltendes medikament |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10338554A1 (de) * | 2003-08-22 | 2005-03-31 | Aventis Pharma Deutschland Gmbh | Pentafluorosulfanylphenyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE102004054847A1 (de) * | 2004-11-13 | 2006-05-24 | Sanofi-Aventis Deutschland Gmbh | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| BRPI0715160A2 (pt) | 2006-08-08 | 2013-06-11 | Sanofi Aventis | imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| KR20110033149A (ko) * | 2008-06-06 | 2011-03-30 | 유씨비 파마, 에스.에이. | 시클로부톡시기를 포함하는 화합물 |
| US8470841B2 (en) | 2008-07-09 | 2013-06-25 | Sanofi | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| ES2443016T3 (es) | 2009-08-26 | 2014-02-17 | Sanofi | Nuevos hidratos cristalinos de fluoroglicósidos heteroaromáticos, productos farmacéuticos que comprenden estos compuestos, y su empleo |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8809325B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| EP2683703B1 (de) | 2011-03-08 | 2015-05-27 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120050A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683701B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| RU2518740C1 (ru) * | 2013-03-22 | 2014-06-10 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" | СРЕДСТВО, ИНГИБИРУЮЩЕЕ Na+/H+-ОБМЕН, И ДИГИДРОХЛОРИД 2-(3,4-МЕТИЛЕНДИОКСИФЕНИЛ)-9-МОРФОЛИНОЭТИЛИМИДАЗО[1,2-a]БЕНЗИМИДАЗОЛА |
| RU2765117C2 (ru) * | 2019-09-24 | 2022-01-25 | Федеральное государственное автономное образовательное учреждение высшего образования "Уральский федеральный университет имени первого Президента России Б.Н. Ельцина" | Применение натриевой соли диэтилового эфира 4-оксо-1,4-дигидропиразоло[5,1-с]-1,2,4-триазин-3,8-дикарбоновой кислоты, моногидрата в качестве средства лечения и профилактики поздних осложнений сахарного диабета |
| CN113274380A (zh) * | 2021-05-13 | 2021-08-20 | 武汉理工大学 | S0859在制备治疗脑缺血再灌注损伤药物中的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4417004A1 (de) * | 1994-05-13 | 1995-11-16 | Hoechst Ag | Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5665739A (en) * | 1992-12-15 | 1997-09-09 | Hoechst Aktiengesellschaft | Substituted benzoylguanidines, process and their preparation, their use as pharmaceutical or diagnostic, and pharmaceutical containing them |
| TW250479B (enExample) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
| US6057322A (en) * | 1995-01-30 | 2000-05-02 | Hoechst Aktiengesellschaft | Basically-substituted benzoylguanidines, a process for preparing them, their use as a medicament or diagnostic agent, and a medicament containing them |
| DE19517848A1 (de) * | 1995-05-16 | 1996-11-21 | Merck Patent Gmbh | Fluorhaltige Benzoylguanidine |
| DE19526381A1 (de) * | 1995-07-19 | 1997-01-23 | Hoechst Ag | 4-Fluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
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2002
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- 2003-06-02 AU AU2003250821A patent/AU2003250821B8/en not_active Ceased
- 2003-06-02 PT PT03759904T patent/PT1515947E/pt unknown
- 2003-06-02 MX MXPA04012231A patent/MXPA04012231A/es active IP Right Grant
- 2003-06-02 EP EP09005497A patent/EP2103598A1/de not_active Withdrawn
- 2003-06-02 BR BR0312134-8A patent/BR0312134A/pt not_active IP Right Cessation
- 2003-06-02 PL PL03372054A patent/PL372054A1/xx not_active Application Discontinuation
- 2003-06-02 RU RU2005100508/04A patent/RU2305093C2/ru not_active IP Right Cessation
- 2003-06-02 ES ES03759904T patent/ES2333216T3/es not_active Expired - Lifetime
- 2003-06-02 RS YUP-1059/04A patent/RS105904A/sr unknown
- 2003-06-02 DE DE50311897T patent/DE50311897D1/de not_active Expired - Lifetime
- 2003-06-02 WO PCT/EP2003/005738 patent/WO2003106410A1/de not_active Ceased
- 2003-06-02 HR HR20041175A patent/HRP20041175A2/xx not_active Application Discontinuation
- 2003-06-02 KR KR10-2004-7020290A patent/KR20050010052A/ko not_active Ceased
- 2003-06-02 CA CA002489245A patent/CA2489245A1/en not_active Abandoned
- 2003-06-02 CN CNB038136139A patent/CN1295213C/zh not_active Expired - Fee Related
- 2003-06-02 EP EP03759904A patent/EP1515947B1/de not_active Expired - Lifetime
- 2003-06-02 JP JP2004513243A patent/JP4383343B2/ja not_active Expired - Lifetime
- 2003-06-11 PE PE2003000580A patent/PE20040559A1/es not_active Application Discontinuation
- 2003-06-11 AR ARP030102093A patent/AR040201A1/es unknown
- 2003-06-11 TW TW092115780A patent/TWI291460B/zh not_active IP Right Cessation
- 2003-06-12 MY MYPI20032196A patent/MY130810A/en unknown
-
2004
- 2004-11-23 ZA ZA200409418A patent/ZA200409418B/xx unknown
- 2004-12-08 MA MA27988A patent/MA27234A1/fr unknown
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2005
- 2005-01-06 NO NO20050078A patent/NO20050078L/no not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4417004A1 (de) * | 1994-05-13 | 1995-11-16 | Hoechst Ag | Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006027130A1 (de) * | 2004-09-11 | 2006-03-16 | Sanofi-Aventis Deutschland Gmbh | Pentafluorsulfanylphenyl-substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum sowie sie enthaltendes medikament |
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