DE102016215240B3 - Mikrodosiereinrichtung und automatisches Mikrodosierverfahren - Google Patents

Mikrodosiereinrichtung und automatisches Mikrodosierverfahren Download PDF

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Publication number
DE102016215240B3
DE102016215240B3 DE102016215240.8A DE102016215240A DE102016215240B3 DE 102016215240 B3 DE102016215240 B3 DE 102016215240B3 DE 102016215240 A DE102016215240 A DE 102016215240A DE 102016215240 B3 DE102016215240 B3 DE 102016215240B3
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liquid
light
jet
intensity
dosing
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German (de)
English (en)
Inventor
Michael Klinger
Christopher LASKE
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Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
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Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
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Priority to DE102016215240.8A priority Critical patent/DE102016215240B3/de
Priority to EP17185313.8A priority patent/EP3285074B1/de
Priority to US15/673,528 priority patent/US11280806B2/en
Priority to JP2017156707A priority patent/JP2018028540A/ja
Priority to CN201710700710.9A priority patent/CN107765022B/zh
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Publication of DE102016215240B3 publication Critical patent/DE102016215240B3/de
Priority to JP2022110380A priority patent/JP7395667B2/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/135—Nozzles
    • B41J2/165—Prevention or detection of nozzle clogging, e.g. cleaning, capping or moistening for nozzles
    • B41J2/16579—Detection means therefor, e.g. for nozzle clogging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/21—Ink jet for multi-colour printing
    • B41J2/2132—Print quality control characterised by dot disposition, e.g. for reducing white stripes or banding
    • B41J2/2142—Detection of malfunctioning nozzles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/06—Means for regulation, monitoring, measurement or control, e.g. flow regulation of illumination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/39—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/061—Counting droplets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0439—Moving fluids with specific forces or mechanical means specific forces vibrational forces ultrasonic vibrations, vibrating piezo elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1044—Using pneumatic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G01N35/1074—Multiple transfer devices arranged in a two-dimensional array

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Computer Hardware Design (AREA)
  • Quality & Reliability (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE102016215240.8A 2016-08-16 2016-08-16 Mikrodosiereinrichtung und automatisches Mikrodosierverfahren Active DE102016215240B3 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE102016215240.8A DE102016215240B3 (de) 2016-08-16 2016-08-16 Mikrodosiereinrichtung und automatisches Mikrodosierverfahren
EP17185313.8A EP3285074B1 (de) 2016-08-16 2017-08-08 Mikrodosiereinrichtung und automatisches mikrodosierverfahren
US15/673,528 US11280806B2 (en) 2016-08-16 2017-08-10 Microdispensing device and automatic microdispensing process
JP2017156707A JP2018028540A (ja) 2016-08-16 2017-08-15 マイクロ分注機構及び自動マイクロ分注方法
CN201710700710.9A CN107765022B (zh) 2016-08-16 2017-08-16 微分配装置和自动微分配方法
JP2022110380A JP7395667B2 (ja) 2016-08-16 2022-07-08 マイクロ分注機構及び自動マイクロ分注方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102016215240.8A DE102016215240B3 (de) 2016-08-16 2016-08-16 Mikrodosiereinrichtung und automatisches Mikrodosierverfahren

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DE102016215240B3 true DE102016215240B3 (de) 2017-10-12

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US (1) US11280806B2 (enExample)
EP (1) EP3285074B1 (enExample)
JP (2) JP2018028540A (enExample)
CN (1) CN107765022B (enExample)
DE (1) DE102016215240B3 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113490547A (zh) * 2018-12-07 2021-10-08 阿尔缇玛基因组学公司 在样品处理和检测期间为受控环境实现屏障
WO2023078748A1 (en) 2021-11-06 2023-05-11 Dispendix Gmbh Carrier device for a dispensing device

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102016215240B3 (de) * 2016-08-16 2017-10-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Mikrodosiereinrichtung und automatisches Mikrodosierverfahren
CN114234538B (zh) * 2021-12-20 2023-03-10 苏州热立方新能源有限公司 一种霜层识别装置及使用方法和探针自动除霜系统
WO2025183831A1 (en) * 2024-02-26 2025-09-04 Ventana Medical Systems, Inc. Precision dispenser actuator
CN119286638A (zh) * 2024-09-25 2025-01-10 吉林省特医食品生物科技有限公司 一种自动滴油装置及控制系统

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328800A (en) * 1980-10-30 1982-05-11 Alvin J. Marx Automated intravenous fluid regulating and administering apparatus
DE4211003A1 (de) * 1991-04-04 1992-10-08 Olympus Optical Co Vorrichtung und verfahren zum detektieren des volumens einer ausgetragenen fluessigkeit
JP2003114104A (ja) * 2001-10-03 2003-04-18 Canon Inc 飛翔物体位置測定方法及び装置
JP2006184161A (ja) * 2004-12-28 2006-07-13 Seiko Epson Corp 計測装置、液滴吐出装置、および計測方法
US20090086190A1 (en) * 2007-09-27 2009-04-02 Kenichi Kodama Liquid droplet measurement apparatus and liquid droplet measurement method
US20160031030A1 (en) * 2013-03-13 2016-02-04 Micronic Mydata AB Method and device for jetting droplets

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6878554B1 (en) * 2000-03-20 2005-04-12 Perkinelmer Las, Inc. Method and apparatus for automatic pin detection in microarray spotting instruments
JP3809086B2 (ja) 2001-10-12 2006-08-16 オリンパス株式会社 液体分注装置
JP2005134167A (ja) 2003-10-29 2005-05-26 National Institute Of Advanced Industrial & Technology スポッタ装置
IL166400A (en) * 2005-01-20 2012-07-31 Flowsense Ltd Optical drop detection system
US7342670B2 (en) * 2005-10-19 2008-03-11 Labcoat, Ltd. In-flight drop location verification system
WO2007056490A2 (en) * 2005-11-08 2007-05-18 Incom, Inc. Fiber optic interrogated microslide, microslide kits and uses thereof
JP4974947B2 (ja) 2007-09-27 2012-07-11 富士フイルム株式会社 液滴測定装置
WO2010044765A1 (en) * 2008-10-15 2010-04-22 Hewlett-Packard Development Company, L. P. Method of detecting drops
US8201913B2 (en) * 2009-04-20 2012-06-19 Hewlett-Packard Development Company, L.P. Drop detector
US8912007B2 (en) * 2013-01-22 2014-12-16 Tecan Trading Ag Optical measuring apparatus and method for the analysis of samples contained in liquid drops
DE102016215240B3 (de) * 2016-08-16 2017-10-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Mikrodosiereinrichtung und automatisches Mikrodosierverfahren

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328800A (en) * 1980-10-30 1982-05-11 Alvin J. Marx Automated intravenous fluid regulating and administering apparatus
DE4211003A1 (de) * 1991-04-04 1992-10-08 Olympus Optical Co Vorrichtung und verfahren zum detektieren des volumens einer ausgetragenen fluessigkeit
JP2003114104A (ja) * 2001-10-03 2003-04-18 Canon Inc 飛翔物体位置測定方法及び装置
JP2006184161A (ja) * 2004-12-28 2006-07-13 Seiko Epson Corp 計測装置、液滴吐出装置、および計測方法
US20090086190A1 (en) * 2007-09-27 2009-04-02 Kenichi Kodama Liquid droplet measurement apparatus and liquid droplet measurement method
US20160031030A1 (en) * 2013-03-13 2016-02-04 Micronic Mydata AB Method and device for jetting droplets

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113490547A (zh) * 2018-12-07 2021-10-08 阿尔缇玛基因组学公司 在样品处理和检测期间为受控环境实现屏障
CN113490547B (zh) * 2018-12-07 2023-07-11 阿尔缇玛基因组学公司 在样品处理和检测期间为受控环境实现屏障
WO2023078748A1 (en) 2021-11-06 2023-05-11 Dispendix Gmbh Carrier device for a dispensing device
LU500832B1 (en) 2021-11-06 2023-05-15 Dispendix Gmbh Carrier Device for a Dispensing Device

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JP2022163728A (ja) 2022-10-26
JP7395667B2 (ja) 2023-12-11
CN107765022B (zh) 2023-02-17
CN107765022A (zh) 2018-03-06
US11280806B2 (en) 2022-03-22
EP3285074B1 (de) 2022-01-12
JP2018028540A (ja) 2018-02-22
EP3285074A1 (de) 2018-02-21
US20180067142A1 (en) 2018-03-08

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